journal of neuroinflammation سال:2011 - دوره:8

Fa | Ar | En


journal of neuroinflammation
سال:2011 - دوره:8 - شماره:0

A dual role for microglia in promoting tissue inhibitor of metalloproteinase (TIMP) expression in glial cells in response to neuroinflammatory stimuli A lack of association between hyperserotonemia and the increased frequency of serum anti-myelin basic protein auto-antibodies in autistic children A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type 1 by glial cells A role for tumor necrosis factor-α in ischemia and ischemic preconditioning Activation of matrix metalloproteinases following anti-Aβ immunotherapy; implications for microhemorrhage occurrence Activation of retinal microglia rather than microglial cell density correlates with retinal neovascularization in the mouse model of oxygen-induced retinopathy Adaptive Müller cell responses to microglial activation mediate neuroprotection and coordinate inflammation in the retina Air pollution and the brain: Subchronic diesel exhaust exposure causes neuroinflammation and elevates early markers of neurodegenerative disease Alteration of T cell cytokine production in PLPp-139-151-induced EAE in SJL mice by an immunostimulatory CpG Oligonucleotide Alzheimer's disease - a neurospirochetosis. Analysis of the evidence following Koch's and Hill's criteria Anandamide inhibits Theiler's virus induced VCAM-1 in brain endothelial cells and reduces leukocyte transmigration in a model of blood brain barrier by activation of CB1receptors Anti-CD20 B-cell depletion enhances monocyte reactivity in neuroimmunological disorders Apolipoprotein E expression is elevated by interleukin 1 and other interleukin 1-induced factors Aspirin-triggered lipoxin A4attenuates LPS-induced pro-inflammatory responses by inhibiting activation of NF-κB and MAPKs in BV-2 microglial cells Atorvastatin prevents age-related and amyloid-β-induced microglial activation by blocking interferon-γ release from natural killer cells in the brain Brain microvascular pericytes are immunoactive in culture: Cytokine,chemokine,nitric oxide,and LRP-1 expression in response to lipopolysaccharide Brain pericytes among cells constituting the blood-brain barrier are highly sensitive to tumor necrosis factor-α,releasing matrix metalloproteinase-9 and migrating in vitro CCL2/MCP-1 modulation of microglial activation and proliferation CD200-CD200R dysfunction exacerbates microglial activation and dopaminergic neurodegeneration in a rat model of Parkinson's disease CRP gene variation affects early development of Alzheimer's disease-related plaques CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease CXCR7 antagonism prevents axonal injury during experimental autoimmune encephalomyelitis as revealed by in vivo axial diffusivity Cannabidiol reduces lipopolysaccharide-induced vascular changes and inflammation in the mouse brain: An intravital microscopy study Cautionary notes on the use of NF-κB p65 and p50 antibodies for CNS studies Central administration of insulin-like growth factor-I decreases depressive-like behavior and brain cytokine expression in mice Cerebral amyloid angiopathy-related inflammation presenting with steroid-responsive higher brain dysfunction: Case report and review of the literature Cerebral ischemia induces microvascular pro-inflammatory cytokine expression via the MEK/ERK pathway Changes in interleukin-1 signal modulators induced by 3,4-methylenedioxymethamphetamine (MDMA): Regulation by CB2 receptors and implications for neurotoxicity Chitotriosidase as a biomarker of cerebral adrenoleukodystrophy Cigarette smoke extract upregulates heme oxygenase-1 via PKC/NADPH oxidase/ROS/PDGFR/PI3K/Akt pathway in mouse brain endothelial cells Classically and alternatively activated bone marrow derived macrophages differ in cytoskeletal functions and migration towards specific CNS cell types Comparing the immunosuppressive potency of naïve marrow stromal cells and Notch-transfected marrow stromal cells Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders Concurrent hippocampal induction of MHC II pathway components and glial activation with advanced aging is not correlated with cognitive impairment Conformational epitopes of myelin oligodendrocyte glycoprotein are targets of potentially pathogenic antibody responses in multiple sclerosis Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease Cooperative contributions of Interferon regulatory factor 1 (IRF1) and IRF8 to interferon-γ-mediated cytotoxic effects on oligodendroglial progenitor cells Curcumin is a potent modulator of microglial gene expression and migration Delayed inflammatory mRNA and protein expression after spinal cord injury Deleterious effects of lymphocytes at the early stage of neurodegeneration in an animal model of amyotrophic lateral sclerosis Developmental regulation of the neuroinflammatory responses to LPS and/or hypoxia-ischemia between preterm and term neonates: An experimental study Differential aquaporin 4 expression during edema build-up and resolution phases of brain inflammation Differential contribution of electrically evoked dorsal root reflexes to peripheral vasodilatation and plasma extravasation Differential regional expression patterns of α-synuclein,TNF-α,and IL-1β and variable status of dopaminergic neurotoxicity in mouse brain after Paraquat treatment Distribution of interleukin-1 receptor complex at the synaptic membrane driven by interleukin-1β and NMDA stimulation ELISA measurement of specific non-antigen-bound antibodies to Aβ1-42 monomer and soluble oligomers in sera from Alzheimer's disease,mild cognitively impaired,and noncognitively impaired subjects Effects of betaine on lipopolysaccharide-induced memory impairment in mice and the involvement of GABA transporter 2 Enhanced neuroinflammation and pain hypersensitivity after peripheral nerve injury in rats expressing mutated superoxide dismutase 1 Estrogens regulate neuroinflammatory genes via estrogen receptors α and β in the frontal cortex of middle-aged female rats Evidence for regulatory diversity and auto-regulation at the TAC1 locus in sensory neurones Exacerbation of CNS inflammation and neurodegeneration by systemic LPS treatment is independent of circulating IL-1β and IL-6 Exogenous nitric oxide decreases brain vascular inflammation,leakage and venular resistance during Plasmodium berghei ANKA infection in mice Expression and cellular localization of cyclooxygenases and prostaglandin E synthases in the hemorrhagic brain Expression of mutant alpha-synuclein modulates microglial phenotype in vitro Expression of sphingosine kinase 1 in amoeboid microglial cells in the corpus callosum of postnatal rats Expression of tumor necrosis factor-α and interleukin-1β genes in the cochlea and inferior colliculus in salicylate-induced tinnitus Fingolimod modulates microglial activation to augment markers of remyelination Generation of reactive oxygen species in 1-methyl-4-phenylpyridinium (MPP+) treated dopaminergic neurons occurs as an NADPH oxidase-dependent two-wave cascade Genomic profile of Toll-like receptor pathways in traumatically brain-injured mice: Effect of exogenous progesterone Gliovascular and cytokine interactions modulate brain endothelial barrier in vitro Granulocyte colony stimulating factor attenuates inflammation in a mouse model of amyotrophic lateral sclerosis HIV-1 Tat activates indoleamine 2,3 dioxygenase in murine organotypic hippocampal slice cultures in a p38 mitogen-activated protein kinase-dependent manner HIV-1 and IL-1β regulate astrocytic CD38 through mitogen-activated protein kinases and nuclear factor-κB signaling mechanisms Heteroarylketones inhibit astroglial interleukin-6 expression via a STAT3/NF-κB signaling pathway Human brain endothelial cells endeavor to immunoregulate CD8 T cells via PD-1 ligand expression in multiple sclerosis IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion,migration and synaptic formation In vivo imaging of lymphocytes in the CNS reveals different behaviour of naïve T cells in health and autoimmunity Increased cerebral (R)-[11C]PK11195 uptake and glutamate release in a rat model of traumatic brain injury: A longitudinal pilot study Increased circulating leukocyte numbers and altered macrophage phenotype correlate with the altered immune response to brain injury in metallothionein (MT) -I/II null mutant mice Increased expression of cystine/glutamate antiporter in multiple sclerosis Increased expression of the chemokines CXCL1 and MIP-1α by resident brain cells precedes neutrophil infiltration in the brain following prolonged soman-induced status epilepticus in rats Increased interleukin-1β levels following low dose MDMA induces tolerance against the 5-HT neurotoxicity produced by challenge MDMA Increased levels of HMGB1 and pro-inflammatory cytokines in children with febrile seizures Increased local concentration of complement C5a contributes to incisional pain in mice Increased neuroinflammatory and arachidonic acid cascade markers,and reduced synaptic proteins,in brain of HIV-1 transgenic rats Increased serum levels of anti-ganglioside M1 auto-antibodies in autistic children: Relation to the disease severity Indications of Th1 and Th17 responses in cerebrospinal fluid from patients with Lyme neuroborreliosis: A large retrospective study Inhibition of interleukin-6 trans-signaling in the brain facilitates recovery from lipopolysaccharide-induced sickness behavior Inhibition of spinal astrocytic c-Jun N-terminal kinase (JNK) activation correlates with the analgesic effects of ketamine in neuropathic pain Inhibitory effect of a tyrosine-fructose Maillard reaction product,2,4-bis(p-hydroxyphenyl)-2-butenal on amyloid-β generation and inflammatory reactions via inhibition of NF-κB and STAT3 activation in cultured astrocytes and microglial BV-2 cells Insulin-like growth factor-I gene delivery to astrocytes reduces their inflammatory response to lipopolysaccharide Insulin-like growth factor-I peptides act centrally to decrease depression-like behavior of mice treated intraperitoneally with lipopolysaccharide Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway Interferon regulatory factor-7 modulates experimental autoimmune encephalomyelitis in mice Interleukin-1 beta and neurotrophin-3 synergistically promote neurite growth in vitro Interleukin-1α expression precedes IL-1β after ischemic brain injury and is localised to areas of focal neuronal loss and penumbral tissues Intracerebral infection with dengue-3 virus induces meningoencephalitis and behavioral changes that precede lethality in mice LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury Lack of macrophage migration inhibitory factor in mice does not affect hallmarks of the inflammatory/immune response during the first week after stroke Lateral fluid percussion injury of the brain induces CCL20 inflammatory chemokine expression in rats Lentiviral vector-mediated stable expression of sTNFR-Fc in human macrophage and neuronal cells as a potential therapy for neuroAIDS Lipocalin 2 in the central nervous system host response to systemic lipopolysaccharide administration Lipopolysaccharide modulates astrocytic S100B secretion: A study in cerebrospinal fluid and astrocyte cultures from rats Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by luminal microvessel IL-6 and GM-CSF Loss of function mutations in the progranulin gene are related to pro-inflammatory cytokine dysregulation in frontotemporal lobar degeneration patients Loss of the receptor tyrosine kinase Axl leads to enhanced inflammation in the CNS and delayed removal of myelin debris during Experimental Autoimmune Encephalomyelitis Low ficolin-3 levels in early follow-up serum samples are associated with the severity and unfavorable outcome of acute ischemic stroke Low plasma progranulin levels in children with autism Lymph node-derived donor encephalitogenic CD4+T cells in C57BL/6 mice adoptive transfer experimental autoimmune encephalomyelitis highly express GM-CSF and T-bet Melittin restores proteasome function in an animal model of ALS Methyl salicylate 2-O-β-D-lactoside,a novel salicylic acid analogue,acts as an anti-inflammatory agent on microglia and astrocytes Microglia use multiple mechanisms to mediate interactions with vitronectin; non-essential roles for the highly-expressed αvβ3 and αvβ5 integrins Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity Microglial p38α MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aβ) Midazolam suppresses interleukin-1β-induced interleukin-6 release from rat glial cells. - صفحه:68- Mild hypothermia causes differential,time-dependent changes in cytokine expression and gliosis following endothelin-1-induced transient focal cerebral ischemia Modulation of spinal cord synaptic activity by tumor necrosis factor α in a model of peripheral neuropathy Momordica charantia (bitter melon) attenuates high-fat diet-associated oxidative stress and neuroinflammation MyD88 is pivotal for immune recognition of Citrobacter koseri and astrocyte activation during CNS infection Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNFα,NFκB,p38 and caspase 8 dependent pathways Myelin down-regulates myelin phagocytosis by microglia and macrophages through interactions between CD47 on myelin and SIRPα (signal regulatory protein-α) on phagocytes Myelin-phagocytosing macrophages modulate autoreactive T cell proliferation Neuro-inflammation,blood-brain barrier,seizures and autism Neuroimmune modulation following traumatic stress in rats: Evidence for an immunoregulatory cascade mediated by c-Src,miRNA222 and PAK1 Neuroinflammation in Alzheimer's disease wanes with age Neuroinflammation induces glial aromatase expression in the uninjured songbird brain Neuropeptide Y inhibits interleukin-1β-induced phagocytosis by microglial cells Neuroprotective response after photodynamic therapy: Role of vascular endothelial growth factor Neurovascular dysfunction,inflammation and endothelial activation: Implications for the pathogenesis of Alzheimer's disease Nogo receptor is involved in the adhesion of dendritic cells to myelin Oral administration of the KATPchannel opener diazoxide ameliorates disease progression in a murine model of multiple sclerosis Origin and consequences of brain Toll-like receptor 4 pathway stimulation in an experimental model of depression Osteoarthritis accelerates and exacerbates Alzheimer's disease pathology in mice Overexpression of serine racemase in retina and overproduction of D-serine in eyes of streptozotocin-induced diabetic retinopathy Overweight worsens apoptosis,neuroinflammation and blood-brain barrier damage after hypoxic ischemia in neonatal brain through JNK hyperactivation P2X7 receptor activation ameliorates CA3 neuronal damage via a tumor necrosis factor-α-mediated pathway in the rat hippocampus following status epilepticus Participation of MCP-induced protein 1 in lipopolysaccharide preconditioning-induced ischemic stroke tolerance by regulating the expression of proinflammatory cytokines Peripheral anti-inflammatory effects explain the ginsenosides paradox between poor brain distribution and anti-depression efficacy Peripheral leukocyte counts and outcomes after intracerebral hemorrhage Plasmacytoid dendritic cells are increased in cerebrospinal fluid of untreated patients during multiple sclerosis relapse Poly(ADP-ribose)polymerase-1 modulates microglial responses to amyloid β Poly(I:C) promotes TNFα/TNFR1-dependent oligodendrocyte death in mixed glial cultures Post-traumatic hypoxia exacerbates neurological deficit,neuroinflammation and cerebral metabolism in rats with diffuse traumatic brain injury Predominance of Th2 polarization by Vitamin D through a STAT6-dependent mechanism Prevention of the β-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures. - صفحه:72- Pro-inflammatory cytokines and lipopolysaccharide induce changes in cell morphology,and upregulation of ERK1/2,iNOS and sPLA2-IIA expression in astrocytes and microglia Pro-inflammatory gene expression and neurotoxic effects of activated microglia are attenuated by absence of CCAAT/enhancer binding protein β Pro-inflammatory gene expression in solid glioblastoma microenvironment and in hypoxic stem cells from human glioblastoma Proinflammatory and proapoptotic markers in relation to mono and di-cations in plasma of autistic patients from Saudi Arabia Protein kinase C-α signals P115RhoGEF phosphorylation and RhoA activation in TNF-α-induced mouse brain microvascular endothelial cell barrier dysfunction Reactive oxygen species drive herpes simplex virus (HSV)-1-induced proinflammatory cytokine production by murine microglia Reduced inflammation accompanies diminished myelin damage and repair in the NG2 null mouse spinal cord Reduced spiral ganglion neuronal loss by adjunctive neurotrophin-3 in experimental pneumococcal meningitis Reduction of neutrophil activity decreases early microvascular injury after subarachnoid haemorrhage Regulation of Toll-like receptor 1 and -2 in neonatal mice brains after hypoxia-ischemia S-Nitrosoglutathione reduces oxidative injury and promotes mechanisms of neurorepair following traumatic brain injury in rats SDF1 in the dorsal corticospinal tract promotes CXCR4+ cell migration after spinal cord injury Selective adenosine A2Areceptor agonists and antagonists protect against spinal cord injury through peripheral and central effects Serum lipid profiles are associated with disability and MRI outcomes in multiple sclerosis Sesamin ameliorates oxidative stress and mortality in kainic acid-induced status epilepticus by inhibition of MAPK and COX-2 activation Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission? Signal pathways in astrocytes activated by cross-talk between of astrocytes and mast cells through CD40-CD40L Sinomenine inhibits microglial activation by Aβ and confers neuroprotection Soybean-derived Bowman-Birk inhibitor inhibits neurotoxicity of LPS-activated macrophages Specific PKC isoforms regulate LPS-stimulated iNOS induction in murine microglial cells Strain-dependent variation in the early transcriptional response to CNS injury using a cortical explant system Systemic inflammatory challenges compromise survival after experimental stroke via augmenting brain inflammation,blood- brain barrier damage and brain oedema independently of infarct size TLR3 signaling is either protective or pathogenic for the development of Theiler's virus-induced demyelinating disease depending on the time of viral infection TLR4 mutation reduces microglial activation,increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease Temporal and sequential changes of glial cells and cytokine expression during neuronal degeneration after transient global ischemia in rats. - صفحه:70- Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice Temporal profiles of age-dependent changes in cytokine mRNA expression and glial cell activation after status epilepticus in postnatal rat hippocampus The CCAAT/enhancer binding protein (C/EBP) δ is differently regulated by fibrillar and oligomeric forms of the Alzheimer amyloid-β peptide The PPAR-γ agonist pioglitazone modulates inflammation and induces neuroprotection in parkinsonian monkeys The acute inflammatory response to intranigral α-synuclein differs significantly from intranigral lipopolysaccharide and is exacerbated by peripheral inflammation The contribution of activated astrocytes to Aβ production: Implications for Alzheimer's disease pathogenesis The effects of high dose interferon-β1a on plasma microparticles: Correlation with MRI parameters The formyl peptide receptor like-1 and scavenger receptor MARCO are involved in glial cell activation in bacterial meningitis The mTOR kinase inhibitor rapamycin decreases iNOS mRNA stability in astrocytes The possible link between the elevated serum levels of neurokinin A and anti-ribosomal P protein antibodies in children with autism The relationship between indoleamine 2,3-dioxygenase activity and post-stroke cognitive impairment The role of the MYD88-dependent pathway in MPTP-induced brain dopaminergic degeneration The role of tumor necrosis factor-α and TNF-α receptors in cerebral arteries following cerebral ischemia in rat Tissue inhibitor of metalloproteinases-3 mediates the death of immature oligodendrocytes via TNF-α/TACE in focal cerebral ischemia in mice Toll-like receptor 2 -196 to -174 del polymorphism influences the susceptibility of Han Chinese people to Alzheimer's disease Toll-like receptors in cerebral ischemic inflammatory injury Transcellular migration of neutrophil granulocytes through the blood-cerebrospinal fluid barrier after infection with Streptococcus suis Transcriptional analysis of rat piriform cortex following exposure to the organophosphonate anticholinesterase sarin and induction of seizures Transcriptional responses of the nerve agent-sensitive brain regions amygdala,hippocampus,piriform cortex,septum,and thalamus following exposure to the organophosphonate anticholinesterase sarin Treatment with gelsolin reduces brain inflammation and apoptotic signaling in mice following thermal injury Up-regulation of dorsal root ganglia BDNF and trkB receptor in inflammatory pain: An in vivo and in vitro study Vascular endothelial growth factor-A (VEGF-A) and chemokine ligand-2 (CCL2) in amyotrophic lateral sclerosis (ALS) patients Vascular endothelial growth factor-A 47 and chemokine ligand-2 (CCL2) in Amyotrophic Lateral Sclerosis (ALS) patients Vascular endothelial growth factor-A and chemokine ligand (CCL2) genes are upregulated in peripheral blood mononuclear cells in Indian amyotrophic lateral sclerosis patients Wallerian degeneration: Gaining perspective on inflammatory events after peripheral nerve injury Wallerian degeneration: The innate-immune response to traumatic nerve injury