plos pathogens سال:2017 - دوره:13

Fa | Ar | En


plos pathogens
سال:2017 - دوره:13 - شماره:5

A central region in the minor capsid protein of papillomaviruses facilitates viral genome tethering and membrane penetration for mitotic nuclear entry A conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 protease A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host A unique profilin-actin interface is important for malaria parasite motility Adaptation of Candida albicans to environmental pH induces cell wall remodelling and enhances innate immune recognition Antifungal Tc17 cells are durable and stable,persisting as long-lasting vaccine memory without plasticity towards IFNγ cells Antigen delivery to dendritic cells shapes human CD4+and CD8+T cell memory responses to Staphylococcus aureus Calmodulin-like proteins localized to the conoid regulate motility and cell invasion by Toxoplasma gondii Candida auris: A rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally Characterization of miR-122-independent propagation of HCV Compartment-specific distribution of human intestinal innate lymphoid cells is altered in HIV patients under effective therapy Controlling transferrin receptor trafficking with GPI-valence in bloodstream stage African trypanosomes Correction to: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial (PLOS Pathogens,(2016),12,1,(e1005381),10.1371/journal.ppat.1005381) Correction to: Fatal Prion Disease in a Mouse Model of Genetic E200K Creutzfeldt-Jakob Disease (PLoS Pathogens,(2011),7,11,(e1002350),10.1371/journal.ppat.1002350) Correction to: Novel decay dynamics revealed for virus-mediated drug activation in cytomegalovirus infection (PLOS Pathogens,(2017),13,4,(e1006299),10.1371/journal.ppat.1006299) Correction to: Oxidation of Helix-3 Methionines Precedes the Formation of PK Resistant PrPSc (PLoS Pathogens,(2010),6,7,(e1000977),10.1371/journal.ppat.1000977) Delineating morbillivirus entry,dissemination and airborne transmission by studying in vivo competition of multicolor canine distemper viruses in ferrets Down regulation of macrophage IFNGR1 exacerbates systemic L. monocytogenes infection Drosophila as a model for homeostatic,antibacterial,and antiviral mechanisms in the gut Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infection Elevated catalase expression in a fungal pathogen is a double-edged sword of iron FAS-associated factor-1 positively regulates type I interferon response to RNA virus infection by targeting NLRX1 Generational distribution of a Candida glabrata population: Resilient old cells prevail,while younger cells dominate in the vulnerable host Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy HIV-1 competition experiments in humanized mice show that APOBEC3H imposes selective pressure and promotes virus adaptation Hepatitis E virus persists in the presence of a type III interferon response Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques Hijacked: Co-option of host behavior by entomophthoralean fungi Leishmania enriettii (Muniz & Medina,1948): A highly diverse parasite is here to stay MHC Ib molecule Qa-1 presents Mycobacterium tuberculosis peptide antigens to CD8+T cells and contributes to protection against infection MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBPβ regulate innate immune signaling,the polarization of macrophages and the trafficking of Mycobacterium tuberculosis to lysosomes during infection Microbiota-induced peritrophic matrix regulates midgut homeostasis and prevents systemic infection of malaria vector mosquitoes Mucosal fluid glycoprotein DMBT1 suppresses twitching motility and virulence of the opportunistic pathogen Pseudomonas aeruginosa Mycobacterium tuberculosis arrests host cycle at the G1/S transition to establish long term infection NLRX1 negatively modulates type I IFN to facilitate KSHV reactivation from latency New opportunities and challenges to engineer disease resistance in cassava,a staple food of African small-holder farmers Paradoxical myeloid-derived suppressor cell reduction in the bone marrow of SIV chronically infected macaques Parallel ClickSeq and Nanopore sequencing elucidates the rapid evolution of defective-interfering RNAs in Flock House virus Phosphorylated STAT5 directly facilitates parvovirus B19 DNA replication in human erythroid progenitors through interaction with the MCM complex PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis Platelet proteome reveals novel pathways of platelet activation and platelet-mediated immunoregulation in dengue Potent and selective inhibition of pathogenic viruses by engineered ubiquitin variants Predicting HIV-1 transmission and antibody neutralization efficacy in vivo from stoichiometric parameters Promiscuous signaling by a regulatory system unique to the pandemic PMEN1 pneumococcal lineage Protein-protein interactions in the RPS4/RRS1 immune receptor complex Proteomic analysis of Biomphalaria glabrata plasma proteins with binding affinity to those expressed by early developing larval Schistosoma mansoni Seminal plasma induces inflammation and enhances HIV-1 replication in human cervical tissue explants Structural and functional dissection reveals distinct roles of Ca2+-binding sites in the giant adhesin SiiE of Salmonella enterica Structural basis of nectin-1 recognition by pseudorabies virus glycoprotein D Structural insights into reptarenavirus cap-snatching machinery Structure of Ca2+-binding protein-6 from Entamoeba histolytica and its involvement in trophozoite proliferation regulation Suppression of IL-12p70 formation by IL-2 or following macrophage depletion causes T-cell autoreactivity leading to CNS demyelination in HSV-1-infected mice Systematic,multiparametric analysis of Mycobacterium tuberculosis intracellular infection offers insight into coordinated virulence Targeting pathogen sterols: Defence and counterdefence? The host ubiquitin-dependent segregase VCP/p97 is required for the onset of human cytomegalovirus replication The murine cytomegalovirus M35 protein antagonizes type I IFN induction downstream of pattern recognition receptors by targeting NF-κB mediated transcription Translocation of the papillomavirus L2/vDNA complex across the limiting membrane requires the onset of mitosis UGGT1 enhances enterovirus 71 pathogenicity by promoting viral RNA synthesis and viral replication Varicella zoster virus glycoprotein C increases chemokine-mediated leukocyte migration