plos genetics سال:2016 - دوره:12

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plos genetics
سال:2016 - دوره:12 - شماره:8

A Checkpoint-Related Function of the MCM Replicative Helicase Is Required to Avert Accumulation of RNA:DNA Hybrids during S-phase and Ensuing DSBs during G2/M A Conserved Nuclear Cyclophilin Is Required for Both RNA Polymerase II Elongation and Co-transcriptional Splicing in Caenorhabditis elegans A Genomic Map of the Effects of Linked Selection in Drosophila A let-7-to-miR-125 MicroRNA Switch Regulates Neuronal Integrity and Lifespan in Drosophila Accelerating Gene Discovery by Phenotyping Whole-Genome Sequenced Multi-mutation Strains and Using the Sequence Kernel Association Test (SKAT) Active Center Control of Termination by RNA Polymerase III and tRNA Gene Transcription Levels In Vivo Arabidopsis Type II Phosphatidylinositol 4-Kinase PI4Kγ5 Regulates Auxin Biosynthesis and Leaf Margin Development through Interacting with Membrane-Bound Transcription Factor ANAC078 Cell-Autonomous and Non-Cell-Autonomous Regulation of a Feeding State-Dependent Chemoreceptor Gene via MEF-2 and bHLH Transcription Factors Combating a Global Threat to a Clonal Crop: Banana Black Sigatoka Pathogen Pseudocercospora fijiensis (Synonym Mycosphaerella fijiensis) Genomes Reveal Clues for Disease Control Combating the Sigatoka Disease Complex on Banana Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD Comparative Genomic Analyses Provide New Insights into the Evolutionary Dynamics of Heterochromatin in Drosophila Comparative Genomics of the Sigatoka Disease Complex on Banana Suggests a Link between Parallel Evolutionary Changes in Pseudocercospora fijiensis and Pseudocercospora eumusae and Increased Virulence on the Banana Host Competing for Iron: Duplication and Amplification of the isd Locus in Staphylococcus lugdunensis HKU09-01 Provides a Competitive Advantage to Overcome Nutritional Limitation Comprehensive Analysis of the Transcriptional and Mutational Landscape of Follicular and Papillary Thyroid Cancers Control of Anther Cell Differentiation by the Small Protein Ligand TPD1 and Its Receptor EMS1 in Arabidopsis Control of Oocyte Reawakening by Kit Determining the Effect of Natural Selection on Linked Neutral Divergence across Species Developmental Functions of miR156-Regulated SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) Genes in Arabidopsis thaliana Downstream Antisense Transcription Predicts Genomic Features That Define the Specific Chromatin Environment at Mammalian Promoters Drosophila Spidey/Kar Regulates Oenocyte Growth via PI3-Kinase Signaling Exploiting Single-Cell Quantitative Data to Map Genetic Variants Having Probabilistic Effects Functional Translational Readthrough: A Systems Biology Perspective Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci Genome-Wide Association Study Reveals Multiple Loci Influencing Normal Human Facial Morphology Genomewide Association Study of African Children Identifies Association of SCHIP1 and PDE8A with Facial Size and Shape Glucose Sensor MdHXK1 Phosphorylates and Stabilizes MdbHLH3 to Promote Anthocyanin Biosynthesis in Apple HAPLESS13-Mediated Trafficking of STRUBBELIG Is Critical for Ovule Development in Arabidopsis High Resolution Genomic Scans Reveal Genetic Architecture Controlling Alcohol Preference in Bidirectionally Selected Rat Model Human Management of a Wild Plant Modulates the Evolutionary Dynamics of a Gene Determining Recessive Resistance to Virus Infection Identification and Functional Testing of ERCC2 Mutations in a Multi-national Cohort of Patients with Familial Breast- and Ovarian Cancer Integrity of Narrow Epithelial Tubes in the C. elegans Excretory System Requires a Transient Luminal Matrix Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2 Investigating the Interplay between Sister Chromatid Cohesion and Homolog Pairing in Drosophila Nuclei Kdm5/Lid Regulates Chromosome Architecture in Meiotic Prophase I Independently of Its Histone Demethylase Activity KdmB,a Jumonji Histone H3 Demethylase,Regulates Genome-Wide H3K4 Trimethylation and Is Required for Normal Induction of Secondary Metabolism in Aspergillus nidulans Linking Core Promoter Classes to Circadian Transcription Maize opaque10 Encodes a Cereal-Specific Protein That Is Essential for the Proper Distribution of Zeins in Endosperm Protein Bodies Mek1 Down Regulates Rad51 Activity during Yeast Meiosis by Phosphorylation of Hed1 Mg2+ Extrusion from Intestinal Epithelia by CNNM Proteins Is Essential for Gonadogenesis via AMPK-TORC1 Signaling in Caenorhabditis elegans Multiple Independent Retroelement Insertions in the Promoter of a Stress Response Gene Have Variable Molecular and Functional Effects in Drosophila Mutational Biases Drive Elevated Rates of Substitution at Regulatory Sites across Cancer Types New Entries in the Lottery of Facial GWAS Discovery On the Trail of Linked Selection Phenotypic Plasticity through Transcriptional Regulation of the Evolutionary Hotspot Gene tan in Drosophila melanogaster ROOT HAIR DEFECTIVE SIX-LIKE Class I Genes Promote Root Hair Development in the Grass Brachypodium distachyon Reprogramming of Normal Fibroblasts into Cancer-Associated Fibroblasts by miRNAs-Mediated CCL2/VEGFA Signaling Smc5/6 Is a Telomere-Associated Complex that Regulates Sir4 Binding and TPE The DUF59 Containing Protein SufT Is Involved in the Maturation of Iron-Sulfur (FeS) Proteins during Conditions of High FeS Cofactor Demand in Staphylococcus aureus The Hippo Pathway Targets Rae1 to Regulate Mitosis and Organ Size and to Feed Back to Regulate Upstream Components Merlin,Hippo,and Warts The Impact of 18 Ancestral and Horizontally-Acquired Regulatory Proteins upon the Transcriptome and sRNA Landscape of Salmonella enterica serovar Typhimurium The Musashi 1 Controls the Splicing of Photoreceptor-Specific Exons in the Vertebrate Retina The Non-coding Mammary Carcinoma Susceptibility Locus,Mcs5c,Regulates Pappa Expression via Age-Specific Chromatin Folding and Allele-Dependent DNA Methylation The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype Tissue- and Time-Specific Expression of Otherwise Identical tRNA Genes Transgenic Expression of the piRNA-Resistant Masculinizer Gene Induces Female-Specific Lethality and Partial Female-to-Male Sex Reversal in the Silkworm,Bombyx mori - صفحه:e1006203- Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I miR-71 and miR-263 Jointly Regulate Target Genes Chitin synthase and Chitinase to Control Locust Molting p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification