plos genetics سال:2016 - دوره:12

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plos genetics
سال:2016 - دوره:12 - شماره:11

A Helping Hand: RNA-Binding Proteins Guide Gene-Binding Choices by Cohesin Complexes A Mutational Hotspot and Strong Selection Contribute to the Order of Mutations Selected for during Escherichia coli Adaptation to the Gut A Novel Tiller Angle Gene,TAC3,together with TAC1 and D2 Largely Determine the Natural Variation of Tiller Angle in Rice Cultivars A Novel Zebrafish ret Heterozygous Model of Hirschsprung Disease Identifies a Functional Role for mapk10 as a Modifier of Enteric Nervous System Phenotype Severity Ancient Out-of-Africa Mitochondrial DNA Variants Associate with Distinct Mitochondrial Gene Expression Patterns Bottom-up Assembly of the Phytochrome Network Budding Yeast Rif1 Controls Genome Integrity by Inhibiting rDNA Replication CDC-42 Orients Cell Migration during Epithelial Intercalation in the Caenorhabditis elegans Epidermis CLOCKWORK ORANGE Enhances PERIOD Mediated Rhythms in Transcriptional Repression by Antagonizing E-box Binding by CLOCK-CYCLE Combgap Promotes Ovarian Niche Development and Chromatin Association of EcR-Binding Regions in BR-C Complex Breakpoints and Template Switching Associated with Non-canonical Termination of Homologous Recombination in Mammalian Cells Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline Distinct Prion Domain Sequences Ensure Efficient Amyloid Propagation by Promoting Chaperone Binding or Processing In Vivo Experimental Evolution Reveals Interplay between Sch9 and Polyploid Stability in Yeast Experimental Evolution of Metabolic Dependency in Bacteria Functional Genomic Analysis of Candida albicans Adherence Reveals a Key Role for the Arp2/3 Complex in Cell Wall Remodelling and Biofilm Formation Genetically Blocking the Zebrafish Pineal Clock Affects Circadian Behavior Genomic Characterization of Metformin Hepatic Response Heads,Shoulders,Elbows,Knees,and Toes: Modular Gdf5 Enhancers Control Different Joints in the Vertebrate Skeleton High-Resolution Genetics Identifies the Lipid Transfer Protein Sec14p as Target for Antifungal Ergolines High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop Human Oocyte-Derived Methylation Differences Persist in the Placenta Revealing Widespread Transient Imprinting Intron Lariat RNA Inhibits MicroRNA Biogenesis by Sequestering the Dicing Complex in Arabidopsis Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling MTV,an ssDNA Protecting Complex Essential for Transposon-Based Telomere Maintenance in Drosophila Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling Mechanisms for Complex Chromosomal Insertions Multi-nucleotide de novo Mutations in Humans Multiple Origins of the Pathogenic Yeast Candida orthopsilosis by Separate Hybridizations between Two Parental Species Myosin phosphatase Fine-tunes Zebrafish Motoneuron Position during Axonogenesis Neuronal Ndrg4 Is Essential for Nodes of Ranvier Organization in Zebrafish Phosphorylation of CBP20 Links MicroRNA to Root Growth in the Ethylene Response Pleiotropic Associations of Allelic Variants in a 2q22 Region with Risks of Major Human Diseases and Mortality Pleiotropic Mechanisms Indicated for Sex Differences in Autism Prion-Associated Toxicity is Rescued by Elimination of Cotranslational Chaperones Programmed Minichromosome Elimination as a Mechanism for Somatic Genome Reduction in Tetrahymena thermophila Proteomic Landscape of Tissue-Specific Cyclin E Functions in Vivo Regional Control of Chromosome Segregation in Pseudomonas aeruginosa Scribbled Optimizes BMP Signaling through Its Receptor Internalization to the Rab5 Endosome and Promote Robust Epithelial Morphogenesis Suggestions from Geroscience for the Genetics of Age-Related Diseases Survey of the Heritability and Sparse Architecture of Gene Expression Traits across Human Tissues The Genetic Architecture of Quantitative Traits Cannot Be Inferred from Variance Component Analysis The Mighty Fruit Fly Moves into Outbred Genetics The Rise of FXR1: Escaping Cellular Senescence in Head and Neck Squamous Cell Carcinoma The Strength of Selection against Neanderthal Introgression The miR165/166 Mediated Regulatory Module Plays Critical Roles in ABA Homeostasis and Response in Arabidopsis thaliana Transcription Factors Encoded on Core and Accessory Chromosomes of Fusarium oxysporum Induce Expression of Effector Genes