plos genetics سال:2010 - دوره:6

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plos genetics
سال:2010 - دوره:6 - شماره:9

A Novel Statistic for Genome-wide interaction analysis A central regulatory system largely controls transcriptional activation and repression responses to phosphate starvation in arabidopsis A negative regulatory loop between MicroRNA and Hox Gene controls posterior identities in Caenorhabditis elegans A single cis element maintains repression of the key developmental regulator Gata2 Accurately assessing the risk of schizophrenia conferred by rare copy-number variation affecting genes with brain function Allelic selection of amplicons in glioblastoma revealed by combining somatic and germline analysis Allelic variation at the 8q23.3 colorectal cancer risk locus functions as a Cis-acting regulator of EIF3H An immune response network associated with blood lipid levels An insect herbivore microbiome with high plant Biomass-degrading capacity Analysis of population structure: A unifying framework and novel methods based on sparse factor analysis Analysis of the basidiomycete Coprinopsis cinerea Reveals conservation of the core meiotic expression Program over half a billion years of evolution Cdc20 Is Critical for Meiosis I and Fertility of Female Mice Chromatin landscape dictates HSF binding to target DNA elements Commercially available outbred mice for genome-wide association studies Comparative genomic hybridization (CGH) Reveals a Neo-X chromosome and biased gene movement in Stalk-eyed flies (Genus Teleopsis) Critical Functions of Rpa3/Ssb3 in S-Phase DNA Damage Responses in Fission Yeast DCAF26,an Adaptor Protein of Cul4-Based E3,Is Essential for DNA Methylation in Neurospora crassa DNMT3L modulates significant and distinct flanking sequence preference for DNA methylation by DNMT3A and DNMT3B in vivo Dementia revealed: Novel chromosome 6 locus for Late-onset alzheimer disease provides genetic evidence for Folate-pathway abnormalities Differentiation of zebrafish melanophores depends on transcription factors AP2 Alpha and AP2 Epsilon Diversity of Eukaryotic DNA replication origins revealed by Genome-wide analysis of chromatin structure ETS-4 is a transcriptional regulator of life Span in Caenorhabditis elegans Effect of Correlated tRNA abundances on translation errors and evolution of codon usage bias Evidence of selection upon genomic GC-content in bacteria Evidence that mutation is universally biased towards AT in bacteria FliO regulation of FliP in the formation of the Salmonella enterica flagellum Frail hypotheses in evolutionary biology Gene-environment interactions at nucleotide resolution Genetic architecture of complex traits and accuracy of genomic Prediction: Coat colour,Milk-fat percentage,and type in holstein cattle as contrasting model traits Genetic deletion of the desmosomal component Desmoplakin promotes tumor microinvasion in a mouse model of pancreatic neuroendocrine carcinogenesis Genetic variants and their interactions in the prediction of increased Pre-clinical carotid atherosclerosis: The cardiovascular risk in young finns study Genome-wide Double-stranded RNA sequencing reveals the functional significance of Base-paired RNAs in Arabidopsis Germline variation controls the architecture of somatic alterations in tumors Identification of early requirements for preplacodal ectoderm and sensory organ development Identification of new genetic risk variants for Type 2 Diabetes Identifying signatures of natural selection in Tibetan and Andean populations using dense genome scan data Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress Inhibition of GSK-3 ameliorates Aβ pathology in an adult-onset Drosophila model of Alzheimer's disease Lactic acidosis triggers starvation response with paradoxical induction of TXNIP through MondoA Long- and short-term selective forces on malaria parasite genomes Longitudinal genome-wide association of cardiovascular disease risk factors in the bogalusa heart study Loss of maternal ATRX results in centromere instability and aneuploidy in the mammalian oocyte and Pre- implantation embryo Mice Doubly-deficient in lysosomal hexosaminidase a and neuraminidase 4 show epileptic crises and rapid neuronal loss Mutational patterns cannot explain genome composition: Are there any neutral sites in the genomes of bacteria? Network analysis identifies ELF3 as a QTL for the shade avoidance response in arabidopsis Optimal strategy for competence differentiation in bacteria Orphan CpG Islands Identify numerous conserved promoters in the mammalian genome Perturbation analysis of heterochromatin-mediated gene silencing and somatic inheritance Preferential re-replication of Drosophila heterochromatin in the absence of geminin Proteomic changes resulting from gene copy number variations in cancer cells Response to mechanical stress is mediated by the TRPA channel painless in the Drosophila heart Rice Snl6,a Cinnamoyl-CoA Reductase-Like Gene Family Member,Is Required for NH1-Mediated Immunity to Xanthomonas oryzae pv. oryzae SNPs associated with cerebrospinal fluid Phospho-tau levels influence rate of decline in alzheimer's disease Synthesizing and salvaging NAD+: Lessons learned from Chlamydomonas reinhardtii The APETALA-2-like transcription factor OsAP2-39 controls key interactions between abscisic acid and gibberellin in rice The Baker's yeast diploid genome is remarkably stable in vegetative growth and meiosis The Histone H3K36 Methyltransferase MES-4 acts epigenetically to transmit the memory of germline gene expression to progeny The SR Protein B52/SRp55 Is Required for DNA Topoisomerase I Recruitment to Chromatin,mRNA Release and Transcription Shutdown The characterization of twenty sequenced human genomes The genome of a pathogenic Rhodococcus: Cooptive virulence underpinned by key gene acquisitions The metabolic enzyme mana reveals a link between cell wall integrity and chromosome morphology The potential for enhancing the power of genetic association studies in African Americans through the reuse of existing genotype data Widespread Over-expression of the X chromosome in sterile F1 hybrid mice dMyc functions downstream of yorkie to promote the supercompetitive behavior of hippo pathway mutant Cells