plos genetics سال:2011 - دوره:7

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plos genetics
سال:2011 - دوره:7 - شماره:7

A functional variant at a prostate cancer predisposition locus at 8q24 is associated with PVT1 expression A rice plastidial Nucleotide sugar epimerase is involved in Galactolipid biosynthesis and improves photosynthetic efficiency A role for phosphatidic acid in the formation of supersized Lipid droplets A systematic screen for tube morphogenesis and branching genes in the Drosophila tracheal system Adaptations to endosymbiosis in a Cnidarian-Dinoflagellate association: Differential gene expression and specific gene duplications Adult circadian behavior in Drosophila requires developmental expression of cycle,but not period An epigenetic switch involving overlapping fur and DNA methylation optimizes expression of a type VI secretion gene cluster Ancestral genes can control the ability of horizontally acquired loci to confer new traits Auxin response Factor2 (ARF2) and its regulated homeodomain gene HB33 mediate abscisic acid response in Arabidopsis Caenorhabditis briggsae recombinant inbred line genotypes reveal inter-strain incompatibility and the evolution of recombination Chd1 remodels chromatin and influences transient DNA methylation at the clock gene frequency Colon stem cell and crypt dynamics exposed by cell lineage reconstruction Complex evolutionary events at a tandem cluster of Arabidopsis thaliana genes resulting in a single-locus genetic incompatibility DAF-12 regulates a connected network of genes to ensure robust developmental decisions Drosophila araucan and caupolican integrate intrinsic and signalling inputs for the acquisition by muscle progenitors of the lateral transverse fate Epistatic relationships in the BRCA1-BRCA2 pathway Expression of Arf tumor suppressor in spermatogonia facilitates meiotic progression in male germ cells FOXP2 regulates gene networks implicated in neurite outgrowth in the developing brain Fine mapping of five loci associated with low-density lipoprotein cholesterol detects variants that double the explained heritability Gene-Based tests of association Genetic anticipation is associated with Telomere shortening in hereditary breast cancer Genetic loci associated with plasma phospholipid N-3 fatty acids: A Meta-Analysis of Genome-Wide association studies from the charge consortium Genome-Wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1 Genome-Wide scan identifies TNIP1,PSORS1C1,and RHOB as novel risk loci for systemic sclerosis Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations Histone crosstalk directed by H2B ubiquitination is required for chromatin boundary integrity Identification of a mutation associated with fatal foal immunodeficiency syndrome in the fell and dales pony Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy Interactions between glucocorticoid treatment and Cis-regulatory polymorphisms contribute to cellular response phenotypes Lgi2 truncation causes a remitting focal epilepsy in dogs Loss of the BMP antagonist,SMOC-1,causes Ophthalmo-acromelic (Waardenburg anophthalmia) syndrome in humans and mice Mechanisms of chromosome number evolution in yeast Molecular mechanisms generating and stabilizing terminal 22q13 deletions in 44 subjects with phelan/mcdermid syndrome NatF contributes to an evolutionary shift in protein N-terminal acetylation and is important for normal chromosome segregation Nonlinear fitness landscape of a molecular pathway Pathologic and phenotypic alterations in a mouse expressing a connexin47 missense mutation that causes Pelizaeus-Merzbacher-like disease in humans Pervasive sign epistasis between conjugative plasmids and Drug-Resistance chromosomal mutations Proteins in the Nutrient-Sensing and DNA damage checkpoint pathways cooperate to restrain mitotic progression following DNA damage Quantitative and qualitative stem rust resistance factors in barley are associated with transcriptional suppression of defense regulons Rare and common regulatory variation in Population-Scale sequenced human genomes Recombination and population structure in salmonella enterica Regulatory Cross-Talk links Vibrio cholerae chromosome II replication and segregation Replication and explorations of High-Order epistasis using a large advanced intercross line pedigree SHH1,a Homeodomain protein required for DNA Methylation,as well as RDR2,RDM4,and Chromatin remodeling factors,associate with RNA Polymerase IV Somatic genetics empowers the mouse for modeling and interrogating developmental and disease processes Stress-induced PARP activation mediates recruitment of Drosophila Mi-2 to promote heat shock gene expression The demoiselle of X-inactivation: 50 years old and as trendy and mesmerising as ever The epistatic relationship between BRCA2 and the other RAD51 mediators in homologous recombination The translation initiation factor eif4e regulates the Sex-Specific expression of the master switch gene Sxl in Drosophila melanogaster Translation reinitiation relies on the interaction between eIFa/TIF32 and progressively folded cis-acting mRNA elements preceding short uORFS Variants in SUP45 and TRM10 underlie natural variation in translation termination efficiency in Saccharomyces cerevisiae