journal of experimental and clinical cancer research سال:2015 - دوره:34

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journal of experimental and clinical cancer research
سال:2015 - دوره:34 - شماره:1

A fresh look at zebrafish from the perspective of cancer research A modified sentinel node and occult lesion localization (SNOLL) technique in non-palpable breast cancer: A pilot study A panel of eight-miRNA signature as a potential biomarker for predicting survival in bladder cancer A pilot study on the impact of known drug-drug interactions in cancer patients A pseudogene-signature in glioma predicts survival A-kinase anchor protein 4 (AKAP4) a promising therapeutic target of colorectal cancer ARE/SUZ12 dual specifically-regulated adenoviral TK/GCV system for CML blast crisis cells Activation of SAPK/JNK mediated the inhibition and reciprocal interaction of DNA methyltransferase 1 and EZH2 by ursolic acid in human lung cancer cells Analysis of the ORFK1 hypervariable regions reveal distinct HHV-8 clustering in Kaposi's sarcoma and non-Kaposi's cases Anti-CD40-induced inflammatory E-cadherin+ dendritic cells enhance T cell responses and antitumour immunity in murine Lewis lung carcinoma Antitumor activity of the multikinase inhibitor regorafenib in patient-derived xenograft models of gastric cancer Associations of chemo- and radio-resistant phenotypes with the gap junction,adhesion and extracellular matrix in a three-dimensional culture model of soft sarcoma BAP31,a promising target for the immunotherapy of malignant melanomas Baicalein increases the expression and reciprocal interplay of RUNX3 and FOXO3a through crosstalk of AMPKα and MEK/ERK1/2 signaling pathways in human non-small cell lung cancer cells Basigin-mediated redistribution of CD98 promotes cell spreading and tumorigenicity in hepatocellular carcinoma Bone metastases in patients with metastatic renal cell carcinoma: Are they always associated with poor prognosis? CCL21-CCR7 promotes the lymph node metastasis of esophageal squamous cell carcinoma by up-regulating MUC1 CMTM4 is frequently downregulated and functions as a tumour suppressor in clear cell renal cell carcinoma CXCR2-CXCL1 axis is correlated with neutrophil infiltration and predicts a poor prognosis in hepatocellular carcinoma Cancer-related CD15/FUT4 overexpression decreases benefit to agents targeting EGFR or VEGF acting as a novel RAF-MEK-ERK kinase downstream regulator in metastatic colorectal cancer Cell death induction by the BH3 mimetic GX15-070 in thyroid carcinoma cells Characterization of genome-wide TFCP2 targets in hepatocellular carcinoma: Implication of targets FN1 and TJP1 in metastasis Chemoprotection of murine hematopoietic cells by combined gene transfer of cytidine deaminase (CDD) and multidrug resistance 1 gene (MDR1) Combination of curcumin and bicalutamide enhanced the growth inhibition of androgen-independent prostate cancer cells through SAPK/JNK and MEK/ERK1/2-mediated targeting NF-κB/p65 and MUC1-C Combined enzyme/prodrug treatment by genetically engineered AT-MSC exerts synergy and inhibits growth of MDA-MB-231 induced lung metastases Confrontation of fibroblasts with cancer cells in vitro: Gene network analysis of transcriptome changes and differential capacity to inhibit tumor growth Contralateral upper tract urothelial carcinoma after nephroureterectomy: The predictive role of DNA methylation Correlation between mutations and mRNA expression of APC and MUTYH genes: New insight into hereditary colorectal polyposis predisposition Crizotinib-induced antitumour activity in human alveolar rhabdomyosarcoma cells is not solely dependent on ALK and MET inhibition DAL-1 attenuates epithelial- to mesenchymal transition in lung cancer DDR2 facilitates hepatocellular carcinoma invasion and metastasis via activating ERK signaling and stabilizing SNAIL1 DEC2 expression is positively correlated with HIF-1 activation and the invasiveness of human osteosarcomas Decreased expression of ARID1A associates with poor prognosis and promotes metastases of hepatocellular carcinoma Developmental pluripotency-associated 4: A novel predictor for prognosis and a potential therapeutic target for colon cancer Do relevant markers of cancer stem cells CD133 and Nestin indicate a poor prognosis in glioma patients? A systematic review and meta-analysis Drug-releasing mesenchymal cells strongly suppress B16 lung metastasis in a syngeneic murine model Dual loading miR-218 mimics and Temozolomide using AuCOOH@FA-CS drug delivery system: Promising targeted anti-tumor drug delivery system with sequential release functions Dual-targeting of aberrant glucose metabolism in glioblastoma EGFR is not a major driver for osteosarcoma cell growth in vitro but contributes to starvation and chemotherapy resistance ERRγ target genes are poor prognostic factors in Tamoxifen-treated breast cancer EZH2 is increased in paediatric T-cell acute lymphoblastic leukemia and is a suitable molecular target in combination treatment approaches Early B-cell factor 3 (EBF3) is a novel tumor suppressor gene with promoter hypermethylation in pediatric acute myeloid leukemia Efficacy of chemotherapy in metastatic male breast cancer patients: A retrospective study Elaboration of a nomogram to predict non sentinel node status in breast cancer patients with positive sentinel node,intra-operatively assessed with one step nucleic acid amplification method Elevated kinesin family member 26B is a prognostic biomarker and a potential therapeutic target for colorectal cancer Endothelial follicle-stimulating hormone receptor expression in invasive breast cancer and vascular remodeling at tumor periphery Erratum: Identification of novel RHPS4-derivative ligands with improved toxicological profiles and telomere-targeting activities (Journal of Experimental & Clinical Cancer Research (2014) 33 (81)) Erratum: Intermittent high dose proton pump inhibitor enhances the antitumor effects of chemotherapy in metastatic breast cancer (Journal of Experimental and Clinical Cancer Research (2015) 34:85 DOI: 10.1186/s13046-015-0194-x) Expression and clinical significance of annexin A2 and human epididymis protein 4 in endometrial carcinoma Extrinsic intestinal denervation modulates tumor development in the small intestine of ApcMin/+ mice Forkhead Box Transcription Factor (FOXO3a) mediates the cytotoxic effect of vernodalin in vitro and inhibits the breast tumor growth in vivo Functional characterization of biodegradable nanoparticles as antigen delivery system Gastric cancer-derived mesenchymal stem cells prompt gastric cancer progression through secretion of interleukin-8 Gene expression profile analyze the molecular mechanism of CXCR7 regulating papillary thyroid carcinoma growth and metastasis Genetic polymorphisms and gene-dosage effect in ovarian cancer risk and response to paclitaxel/cisplatin chemotherapy HOXD9 promotes epithelial-mesenchymal transition and cancer metastasis by ZEB1 regulation in hepatocellular carcinoma Halofuginone inhibits phosphorylation of SMAD-2 reducing angiogenesis and leukemia burden in an acute promyelocytic leukemia mouse model Hematopoietic neoplasms in Prkar2a-deficient mice Hepatitis C virus core protein modulates pRb2/p130 expression in human hepatocellular carcinoma cell lines through promoter methylation Heterozygote of TAP1 Codon637 decreases susceptibility to HPV infection but increases susceptibility to esophageal cancer among the Kazakh populations High expression of DDR1 is associated with the poor prognosis in Chinese patients with pancreatic ductal adenocarcinoma Huachansu suppresses human bladder cancer cell growth through the Fas/Fasl and TNF-α/TNFR1 pathway in vitro and in vivo Hyperphosphorylation of ribosomal protein S6 predicts unfavorable clinical survival in non-small cell lung cancer Hypoxia-inducible MiR-182 promotes angiogenesis by targeting RASA1 in hepatocellular carcinoma Icaritin induces lytic cytotoxicity in extranodal NK/T-cell lymphoma Identification and validation of potential prognostic lncRNA biomarkers for predicting survival in patients with multiple myeloma Immunoreactivity of the fully humanized therapeutic antibody PankoMab-GEX™ is an independent prognostic marker for breast cancer patients Inactivation of PI3-K/Akt and reduction of SP1 and p65 expression increase the effect of solamargine on suppressing EP4 expression in human lung cancer cells Increased HMGB1 and cleaved caspase-3 stimulate the proliferation of tumor cells and are correlated with the poor prognosis in colorectal cancer Inhibition of MTA1 by ERα contributes to protection hepatocellular carcinoma from tumor proliferation and metastasis Inhibition of autophagy by 3-MA enhances IL-24-induced apoptosis in human oral squamous cell carcinoma cells Inhibition of oleandrin on the proliferation show and invasion of osteosarcoma cells in vitro by suppressing Wnt/β-catenin signaling pathway Innovation in catheter design for intra-arterial liver cancer treatments results in favorable particle-fluid dynamics Integrated analysis of genome-wide DNA methylation,gene expression and protein expression profiles in molecular subtypes of WHO II-IV gliomas Intermittent high dose proton pump inhibitor enhances the antitumor effects of chemotherapy in metastatic breast cancer Intertumor heterogeneity in vascularity and invasiveness of artificial melanoma brain metastases KRAS testing of patients with metastatic colorectal cancer in a community-based oncology setting: A retrospective database analysis Karyopherin alpha 2 is a novel prognostic marker and a potential therapeutic target for colon cancer LDOC1 inhibits proliferation and promotes apoptosis by repressing NF-κB activation in papillary thyroid carcinoma Linc00152 promotes proliferation in gastric cancer through the EGFR-dependent pathway Long non-coding RNA Loc554202 induces apoptosis in colorectal cancer cells via the caspase cleavage cascades Long non-coding RNA MEG3 functions as a competing endogenous RNA to regulate gastric cancer progression Long noncoding RNA CCAT1 promotes hepatocellular carcinoma progression by functioning as let-7 sponge Long noncoding RNA lncTCF7,induced by IL-6/STAT3 transactivation,promotes hepatocellular carcinoma aggressiveness through epithelial-mesenchymal transition Loss of the endothelial glycocalyx is associated with increased E-selectin mediated adhesion of lung tumour cells to the brain microvascular endothelium Low expression of microRNA-204 (MIR-204) is associated with poor clinical outcome of acute myeloid leukemia (AML) patients MTA1 promotes metastasis of MPM via suppression of E-cadherin MTA1-upregulated EpCAM is associated with metastatic behaviors and poor prognosis in lung cancer Metabolic reprogramming: The emerging concept and associated therapeutic strategies Metformin can block precancerous progression to invasive tumors of bladder through inhibiting STAT3-mediated signaling pathways Methylation status of insulin-like growth factor-binding protein 7 concurs with the malignance of oral tongue cancer MiR-203 down-regulates Rap1A and suppresses cell proliferation,adhesion and invasion in prostate cancer MiR-223 promotes the cisplatin resistance of human gastric cancer cells via regulating cell cycle by targeting FBXW7 MiR-24 functions as a tumor suppressor in nasopharyngeal carcinoma through targeting FSCN1 MiR-27b-3p suppresses cell proliferation through targeting receptor tyrosine kinase like orphan receptor 1 in gastric cancer MiR-96 suppresses renal cell carcinoma invasion via downregulation of Ezrin expression MicroRNA-106b promotes colorectal cancer cell migration and invasion by directly targeting DLC1 MicroRNA-144 inhibits the metastasis of gastric cancer by targeting MET expression MicroRNA-184 inhibits cell proliferation and invasion,and specifically targets TNFAIP2 in Glioma MicroRNA-195 suppresses tumor cell proliferation and metastasis by directly targeting BCOX1 in prostate carcinoma MicroRNA-29b attenuates non-small cell lung cancer metastasis by targeting matrix metalloproteinase 2 and PTEN MicroRNA-93 promotes cell proliferation via targeting of PTEN in Osteosarcoma cells Morusin suppresses breast cancer cell growth in vitro and in vivo through C/EBPβ and PPARγ mediated lipoapoptosis Mutation status concordance between primary lesions and metastatic sites of advanced non-small-cell lung cancer and the impact of mutation testing methodologies: a literature review Nectin-4 expression contributes to tumor proliferation,angiogenesis and patient prognosis in human pancreatic cancer Negatively charged AuNP modified with monoclonal antibody against novel tumor antigen FAT1 for tumor targeting Neuron navigator 2 overexpression indicates poor prognosis of colorectal cancer and promotes invasion through the SSH1L/cofilin-1 pathway New trends for overcoming ABCG2/BCRP-mediated resistance to cancer therapies Oncolytic Newcastle disease virus expressing chimeric antibody enhanced anti-tumor efficacy in orthotopic hepatoma-bearing mice Oncolytic tanapoxvirus expressing FliC causes regression of human colorectal cancer xenografts in nude mice Overexpression of P21-activated kinase 4 is associated with poor prognosis in non-small cell lung cancer and promotes migration and invasion Overexpression of TMEM158 contributes to ovarian carcinogenesis PCA3 in prostate cancer and tumor aggressiveness detection on 407 high-risk patients: A National Cancer Institute experience PRX1 knockdown potentiates vitamin K3 toxicity in cancer cells: A potential new therapeutic perspective for an old drug Peritumoural neutrophils negatively regulate adaptive immunity via the PD-L1/PD-1 signalling pathway in hepatocellular carcinoma Phenotype plasticity rather than repopulation from CD90/CK14+ cancer stem cells leads to cisplatin resistance of urothelial carcinoma cell lines Phosphorylated AKT1 is associated with poor prognosis in esophageal squamous cell carcinoma Piwi-interacting RNAs as novel prognostic markers in clear cell renal cell carcinomas Plasma levels of microRNA-24,microRNA-320a,and microRNA-423-5p are potential biomarkers for colorectal carcinoma Polymeric nanocapsules prevent oxidation of core-loaded molecules: Evidence based on the effects of docosahexaenoic acid and neuroprostane on breast cancer cells proliferation Primitive sarcoma of the breast: New insight on the proper surgical management Proton pump inhibitors for the treatment of cancer in companion animals Quantitative detection of DNMT3A R882H mutation in acute myeloid leukemia Quantitative discrimination between invasive ductal carcinomas and benign lesions based on semi-automatic analysis of time intensity curves from breast dynamic contrast enhanced MRI ROS-p53-cyclophilin-D signaling mediates salinomycin-induced glioma cell necrosis Relationship between circulating syndecan-1 levels (CD138s) and serum free light chains in monoclonal gammopathies Resistance to multikinase inhibitor actions mediated by insulin like growth factor-1 SULF2 overexpression positively regulates tumorigenicity of human prostate cancer cells Second-line chemotherapy in advanced biliary cancer progressed to first-line platinum-gemcitabine combination: A multicenter survey and pooled analysis with published data Short hairpin RNA- mediated gene knockdown of FOXM1 inhibits the proliferation and metastasis of human colon cancer cells through reversal of epithelial-to-mesenchymal transformation Signaling by exosomal microRNAs in cancer Skin-reducing mastectomy and immediate breast reconstruction in patients with macromastia Small nucleolar RNA 78 promotes the tumorigenesis in non-small cell lung cancer Solitomab,an EpCAM/CD3 bispecific antibody construct (BiTE®),is highly active against primary uterine and ovarian carcinosarcoma cell lines in vitro Synergistic effects of the sesquiterpene lactone,EPD,with cisplatin and paclitaxel in ovarian cancer cells T-type calcium channel antagonists,mibefradil and NNC-55-0396 inhibit cell proliferation and induce cell apoptosis in leukemia cell lines Targeted inhibition of MEK1 by cobimetinib leads to differentiation and apoptosis in neuroblastoma cells Targeting sphingosine kinase 2 (SphK2) by ABC294640 inhibits colorectal cancer cell growth in vitro and in vivo Telomere length and telomerase activity in non-small cell lung cancer prognosis: clinical usefulness of a specific telomere status The anti-tumor efficacy of 2-deoxyglucose and D-allose are enhanced with p38 inhibition in pancreatic and ovarian cell lines The beneficial effect of Zinc(II) on low-dose chemotherapeutic sensitivity involves p53 activation in wild-type p53-carrying colorectal cancer cells The candidate oncogene (MCRS1) promotes the growth of human lung cancer cells via the miR-155-Rb1 pathway The efficacy of a photolyase-based device on the cancerization field: A clinical and thermographic study The frequency of osteolytic bone metastasis is determined by conditions of the soil,not the number of seeds; evidence from in vivo models of breast and prostate cancer The impact of insulin on chemotherapeutic sensitivity to 5-fluorouracil in gastric cancer cell lines SGC7901,MKN45 and MKN28 The kinase inhibitor D11 induces caspase-mediated cell death in cancer cells resistant to chemotherapeutic treatment The mutation rates of EGFR in non-small cell lung cancer and KRAS in colorectal cancer of Chinese patients as detected by pyrosequencing using a novel dispensation order The number of polyploid giant cancer cells and epithelial-mesenchymal transition-related proteins are associated with invasion and metastasis in human breast cancer The relevance of cell type- and tumor zone-specific VEGFR-2 activation in locally advanced colon cancer Therapeutic potential of antiviral drugs targeting chemorefractory colorectal adenocarcinoma cells overexpressing endogenous retroviral elements Tivantinib induces G2/M arrest and apoptosis by disrupting tubulin polymerization in hepatocellular carcinoma Tumor progression locus 2 ablation suppressed hepatocellular carcinoma development by inhibiting hepatic inflammation and steatosis in mice Ubiquitinated proteins enriched from tumor cells by a ubiquitin binding protein Vx3(A7) as a potent cancer vaccine Up-regulation of activating and inhibitory NKG2 receptors in allogeneic and autologous hematopoietic stem cell grafts Up-regulation of long noncoding RNA MALAT1 contributes to proliferation and metastasis in esophageal squamous cell carcinoma Vitamin D3 enhances the tumouricidal effects of 5-Fluorouracil through multipathway mechanisms in azoxymethane rat model of colon cancer WT1-AS promotes cell apoptosis in hepatocellular carcinoma through down-regulating of WT1 YY1 regulates melanoma tumorigenesis through a MIR-9∈~∈RYBP axis sE-cadherin serves as a diagnostic and predictive parameter in prostate cancer patients