plos pathogens سال:2011 - دوره:7

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plos pathogens
سال:2011 - دوره:7 - شماره:2

A fresh look at the origin of Plasmodium falciparum,the most malignant malaria agent A viral microRNA cluster strongly potentiates the transforming properties of a human herpesvirus Atypical/Nor98 scrapie infectivity in sheep peripheral tissues BosR (BB0647) controls the RpoN-RpoS regulatory pathway and virulence expression in Borrelia burgdorferi by a novel DNA-binding mechanism Charge-surrounded pockets and electrostatic interactions with small ions modulate the activity of retroviral fusion proteins Compensatory evolution of pbp mutations restores the fitness cost imposed by β-lactam resistance in streptococcus pneumoniae Critical role of the virus-encoded microRNA-155 ortholog in the induction of marek's disease lymphomas DC-SIGN mediated sphingomyelinase-activation and ceramide generation is essential for enhancement of viral uptake in dendritic cells DNA damage and reactive nitrogen species are barriers to Vibrio cholerae colonization of the infant mouse intestine Elite suppressors harbor low levels of integrated HIV DNA and high levels of 2-LTR circular HIV DNA compared to HIV+ patients on and off HAART Entrapment of viral capsids in nuclear PML cages is an intrinsic antiviral host defense against Varicella-zoster virus Episomal viral cDNAS identify a reservoir that fuels viral rebound after treatment interruption and that contributes to treatment failure Epstein-Barr virus nuclear antigen 3c facilitates G1-S transition by stabilizing and enhancing the function of Cyclin D1 Expression of P. falciparum var genes involves exchange of the histone variant H2A.Z at the promoter Functional coupling between HIV-1 integrase and the SWI/SNF chromatin remodeling complex for efficient in vitro integration into stable nucleosomes Genetic mapping identifies novel highly protective antigens for an apicomplexan parasite Genital tract sequestration of SIV following acute infection HTLV-1 bZIP factor induces T-cell lymphoma and systemic inflammation in vivo Highly efficient protein misfolding cyclic amplification In situ photodegradation of incorporated polyanion does not alter prion infectivity Inhibition of Nox2 oxidase activity ameliorates influenza a virus-induced lung inflammation Innate sensing of HIV-infected cells Measles outbreak in Africa-is there a link to the HIV-1 epidemic? NS2 protein of hepatitis C virus interacts with structural and non-structural proteins towards virus assembly New models of microsporidiosis: Infections in zebrafish,c. elegans,and honey bee Phosphatidylinositol 3-monophosphate is involved in Toxoplasma apicoplast biogenesis Positive signature-tagged mutagenesis in Pseudomonas aeruginosa: Tracking patho-adaptive mutations promoting airways chronic infection Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection STAT2 mediates innate immunity to dengue virus in the absence of STAT1 via the type I interferon receptor Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila Short-lived IFN-γ effector responses,but long-lived IL-10 memory responses,to malaria in an area of low malaria endemicity Small molecule inhibitors of staphylococcus aureus RnpA alter cellular mRNA turnover,exhibit antimicrobial activity,and attenuate pathogenesis Targeted disruption of py235ebp-1: Invasion of erythrocytes by Plasmodium yoelii using an alternative py235 erythrocyte binding protein The C-terminal domain of the arabinosyltransferase mycobacterium tuberculosis EmbC is a lectin-like carbohydrate binding module The C-terminus of Toxoplasma RON2 provides the crucial link between AMA1 and the host-associated invasion complex The ESCRT-0 component HRS is required for HIV-1 Vpu-mediated BST-2/tetherin down-regulation The RON2-AMA1 interaction is a critical step in moving junction-dependent invasion by apicomplexan parasites The Rubella virus capsid is an anti-apoptotic protein that attenuates the pore-forming ability of Bax The bZIP transcription factor MoAP1 mediates the oxidative stress response and is critical for pathogenicity of the rice blast fungus magnaporthe oryzae The genotype of early-transmitting hiv gp120s promotes α4β7 -reactivity,revealing α4β7+/CD4+ T cells as key targets in mucosal transmission Transcription and translation products of the cytolysin gene psm-mec on the mobile genetic element SCCmec regulate Staphylococcus aureus virulence Trivalent adenovirus type 5 HIV recombinant vaccine primes for modest cytotoxic capacity that is greatest in humans with protective HLA class I alleles Type I interferon signaling regulates Ly6Chi monocytes and neutrophils during acute viral pneumonia in mice Uropathogenic escherichia coli P and type 1 fimbriae act in synergy in a living host to facilitate renal colonization leading to nephron obstruction Whole-body analysis of a viral infection: Vascular endothelium is a primary target of Infectious Hematopoietic Necrosis Virus in zebrafish larvae Wolbachia infections in Anopheles gambiae cells: Transcriptomic characterization of a novel host-symbiont interaction