plos genetics سال:2017 - دوره:13

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plos genetics
سال:2017 - دوره:13 - شماره:10

A C-terminally truncated form of β-catenin acts as a novel regulator of Wnt/β-catenin signaling in planarians A bacterial toxin-antitoxin module is the origin of inter-bacterial and inter-kingdom effectors of Bartonella A dominant-negative mutant inhibits multiple prion variants through a common mechanism A systems level approach to temporal expression dynamics in Drosophila reveals clusters of long term memory genes A trehalose biosynthetic enzyme doubles as an osmotic stress sensor to regulate bacterial morphogenesis Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis AtHKT1 drives adaptation of Arabidopsis thaliana to salinity by reducing floral sodium content BAK1 is involved in AtRALF1-induced inhibition of root cell expansion BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment Broadening the functionality of a J-protein/Hsp70 molecular chaperone system Combinatorial action of Grainyhead,Extradenticle and Notch in regulating Hox mediated apoptosis in Drosophila larval CNS Common,low-frequency,and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study Condensin II and GAIT complexes cooperate to restrict LINE-1 retrotransposition in epithelial cells Defective replication initiation results in locus specific chromosome breakage and a ribosomal RNA deficiency in yeast Division-induced DNA double strand breaks in the chromosome terminus region of Escherichia coli lacking RecBCD DNA repair enzyme Dopamine negatively modulates the NCA ion channels in C. elegans Environmental perturbations lead to extensive directional shifts in RNA processing Functional convergence of histone methyltransferases EHMT1 and KMT2C involved in intellectual disability and autism spectrum disorder G protein-coupled estrogen receptor regulates embryonic heart rate in zebrafish Genetic anticipation in Swedish Lynch syndrome families Genetic epidemiology and Mendelian randomization for informing disease therapeutics: Conceptual and methodological challenges Genetic modifiers of muscular dystrophy act on sarcolemmal resealing and recovery from injury Genomics of parallel adaptation at two timescales in Drosophila Guidelines for morpholino use in zebrafish Involvement of DNA mismatch repair in the maintenance of heterochromatic DNA stability in Saccharomyces cerevisiae Loss of Xist RNA from the inactive X during B cell development is restored in a dynamic YY1-dependent two-step process in activated B cells MiR-125a Is a critical modulator for neutrophil development Non-muscle myosin IIB (Myh10) is required for epicardial function and coronary vessel formation during mammalian development Profiling RNA-Seq at multiple resolutions markedly increases the number of causal eQTLs in autoimmune disease Quantifying connectivity between local Plasmodium falciparum malaria parasite populations using identity by descent RhoGEF9 splice isoforms influence neuronal maturation and synapse formation downstream of α2 GABAAreceptors Rnr1,but not Rnr3,facilitates the sustained telomerase-dependent elongation of telomeres Role of Neuropilin-1/Semaphorin-3A signaling in the functional and morphological integrity of the cochlea Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos SNPs near the cysteine proteinase cathepsin O gene (CTSO) determine tamoxifen sensitivity in ERα-positive breast cancer through regulation of BRCA1 STAT,Wingless,and Nurf-38 determine the accuracy of regeneration after radiation damage in Drosophila The GYF domain protein PSIG1 dampens the induction of cell death during plant-pathogen interactions The blue light-induced interaction of cryptochrome 1 with COP1 requires SPA proteins during Arabidopsis light signaling The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito The homeodomain-interacting protein kinase HPK-1 preserves protein homeostasis and longevity through master regulatory control of the HSF-1 chaperone network and TORC1-restricted autophagy in Caenorhabditis elegans dOCRL maintains immune cell quiescence by regulating endosomal traffic