plos genetics سال:2015 - دوره:11

Fa | Ar | En


plos genetics
سال:2015 - دوره:11 - شماره:1

A Discrete Transition Zone Organizes the Topological and Regulatory Autonomy of the Adjacent Tfap2c and Bmp7 Genes A Genetic Strategy for Probing the Functional Diversity of Magnetosome Formation A Polyubiquitin Chain Reaction: Parkin Recruitment to Damaged Mitochondria A Re-examination of the Selection of the Sensory Organ Precursor of the Bristle Sensilla of Drosophila melanogaster A Regulatory Hierarchy Controls the Dynamic Transcriptional Response to Extreme Oxidative Stress in Archaea A Truncated NLR Protein,TIR-NBS2,Is Required for Activated Defense Responses in the exo70B1 Mutant A dPIP5K Dependent Pool of Phosphatidylinositol 4,5 Bisphosphate (PIP2) Is Required for G-Protein Coupled Signal Transduction in Drosophila Photoreceptors ALIX and ESCRT-III Coordinately Control Cytokinetic Abscission during Germline Stem Cell Division In Vivo ASAR15,A cis-Acting Locus that Controls Chromosome-Wide Replication Timing and Stability of Human Chromosome 15 Aberrant Gene Expression in Humans Altered Ca2+ Kinetics Associated with α-Actinin-3 Deficiency May Explain Positive Selection for ACTN3 Null Allele in Human Evolution An AP Endonuclease Functions in Active DNA Dimethylation and Gene Imprinting in Arabidopsis An Intracellular Transcriptomic Atlas of the Giant Coenocyte Caulerpa taxifolia Antagonistic Cross-Regulation between Sox9 and Sox10 Controls an Anti-tumorigenic Program in Melanoma Ataxin-3,DNA Damage Repair,and SCA3 Cerebellar Degeneration: On the Path to Parsimony? Century-scale Methylome Stability in a Recently Diverged Arabidopsis thaliana Lineage DNA Damage Response Factors from Diverse Pathways,Including DNA Crosslink Repair,Mediate Alternative End Joining Deciphering the Genetic Programme Triggering Timely and Spatially-Regulated Chitin Deposition Developmental Regulation of the Tetrahymena thermophila Origin Recognition Complex Elevated Mutation Rate during Meiosis in Saccharomyces cerevisiae End of the Beginning: Elongation and Termination Features of Alternative Modes of Chromosomal Replication Initiation in Bacteria Estrogenic Exposure Alters the Spermatogonial Stem Cells in the Developing Testis,Permanently Reducing Crossover Levels in the Adult Evolutionary Constraint and Disease Associations of Post-Translational Modification Sites in Human Genomes Fascin1-Dependent Filopodia are Required for Directional Migration of a Subset of Neural Crest Cells Functional Interplay between the 53BP1-Ortholog Rad9 and the Mre11 Complex Regulates Resection,End-Tethering and Repair of a Double-Strand Break Genetic Mapping of MAPK-Mediated Complex Traits Across S. cerevisiae Genetic Variants Modulating CRIPTO Serum Levels Identified by Genome-Wide Association Study in Cilento Isolates Genetic Variation in the Nuclear and Organellar Genomes Modulates Stochastic Variation in the Metabolome,Growth,and Defense Heterologous Aggregates Promote De Novo Prion Appearance via More than One Mechanism Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus Imputation of the Rare HOXB13 G84E Mutation and Cancer Risk in a Large Population-Based Cohort Inactivation of PNKP by Mutant ATXN3 Triggers Apoptosis by Activating the DNA Damage-Response Pathway in SCA3 Insight in Genome-Wide Association of Metabolite Quantitative Traits by Exome Sequence Analyses Integrative Analysis of DNA Methylation and Gene Expression Data Identifies EPAS1 as a Key Regulator of COPD Interactions of Chromatin Context,Binding Site Sequence Content,and Sequence Evolution in Stress-Induced p53 Occupancy and Transactivation MiR-24 Is Required for Hematopoietic Differentiation of Mouse Embryonic Stem Cells Naturally Occurring Differences in CENH3 Affect Chromosome Segregation in Zygotic Mitosis of Hybrids Nicotiana Small RNA Sequences Support a Host Genome Origin of Cucumber Mosaic Virus Satellite RNA No Evidence for Association of Autism with Rare Heterozygous Point Mutations in Contactin-Associated Protein-Like 2 (CNTNAP2),or in Other Contactin-Associated Proteins or Contactins Nur1 Dephosphorylation Confers Positive Feedback to Mitotic Exit Phosphatase Activation in Budding Yeast Origins of Context-Dependent Gene Repression by Capicua PRDM9 Drives Evolutionary Erosion of Hotspots in Mus musculus through Haplotype-Specific Initiation of Meiotic Recombination Phosphorylation of Elp1 by Hrr25 Is Required for Elongator-Dependent tRNA Modification in Yeast Polycomb Protein SCML2 Associates with USP7 and Counteracts Histone H2A Ubiquitination in the XY Chromatin during Male Meiosis Proteasomes,Sir2,and Hxk2 Form an Interconnected Aging Network That Impinges on the AMPK/Snf1-Regulated Transcriptional Repressor Mig1 Protein Poly(ADP-ribosyl)ation Regulates Arabidopsis Immune Gene Expression and Defense Responses RecFOR Is Not Required for Pneumococcal Transformation but Together with XerS for Resolution of Chromosome Dimers Frequently Formed in the Process Regulating Maf1 Expression and Its Expanding Biological Functions Sumoylation Influences DNA Break Repair Partly by Increasing the Solubility of a Conserved End Resection Protein The Arabidopsis SWI2/SNF2 Chromatin Remodeler BRAHMA Regulates Polycomb Function during Vegetative Development and Directly Activates the Flowering Repressor Gene SVP The Combination of Random Mutagenesis and Sequencing Highlight the Role of Unexpected Genes in an Intractable Organism The Genetic and Mechanistic Basis for Variation in Gene Regulation The Global Regulatory Architecture of Transcription during the Caulobacter Cell Cycle The Intersection of the Extrinsic Hedgehog and WNT/Wingless Signals with the Intrinsic Hox Code Underpins Branching Pattern and Tube Shape Diversity in the Drosophila Airways The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3’-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis The Tumor Suppressor BCL7B Functions in the Wnt Signaling Pathway The Yeast La Related Protein Slf1p Is a Key Activator of Translation during the Oxidative Stress Response Tissue-Specific Effects of Genetic and Epigenetic Variation on Gene Regulation and Splicing Transcriptional Control of an Essential Ribozyme in Drosophila Reveals an Ancient Evolutionary Divide in Animals Transposable Elements Contribute to Activation of Maize Genes in Response to Abiotic Stress hnRNP K Coordinates Transcriptional Silencing by SETDB1 in Embryonic Stem Cells α-Actinin-3: Why Gene Loss Is an Evolutionary Gain