plos genetics سال:2012 - دوره:8

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plos genetics
سال:2012 - دوره:8 - شماره:4

A companion cell-dominant and developmentally regulated H3K4 demethylase controls flowering time in Arabidopsis via the repression of FLC expression A coordinated interdependent protein circuitry stabilizes the kinetochore ensemble to protect CENP-A in the human pathogenic yeast Candida albicans A genome-wide screen for genetic variants that modify the recruitment of REST to its target genes A new role for translation initiation factor 2 in maintaining genome integrity A shared role for RBF1 and dCAP-D3 in the regulation of transcription with consequences for innate immunity An unbiased assessment of the role of imprinted genes in an intergenerational model of developmental programming Budding yeast Dma proteins control septin dynamics and the spindle position checkpoint by promoting the recruitment of the Elm1 kinase to the bud neck Cell contact-dependent outer membrane exchange in myxobacteria: Genetic determinants and mechanism Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma Competition between replicative and translesion polymerases during homologous recombination repair in Drosophila Context-dependent dual role of SKI8 homologs in mRNA synthesis and turnover Coordinate regulation of lipid metabolism by novel nuclear receptor partnerships Deep sequencing of plant and animal DNA contained within traditional Chinese medicines reveals legality issues and health safety concerns Defective membrane remodeling in neuromuscular diseases: Insights from animal models Differing requirements for RAD51 and DMC1 in meiotic pairing of centromeres and chromosome arms in Arabidopsis thaliana Dissection of Pol II Trigger Loop function and Pol II activity-dependent control of start site selection in vivo Dynamics of brassinosteroid response modulated by negative regulator LIC in rice Dyschronic,a Drosophila homolog of a deaf-blindness gene,regulates circadian output and slowpoke channels Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population Fine-scale mapping of natural variation in fly fecundity identifies neuronal domain of expression and function of an aquaporin Formation of rigid,non-flight forewings (Elytra) of a beetle requires two major cuticular proteins Genetic inhibition of solute-linked carrier 39 family transporter 1 ameliorates Aβ pathology in a Drosophila model of Alzheimer's disease Genome-wide patterns of Arabidopsis gene expression in nature Hypoxia disruption of vertebrate CNS pathfinding through EphrinB2 is rescued by magnesium Improved statistics for genome-wide interaction analysis Insulin signaling mediates sexual attractiveness in Drosophila Long-range chromosome organization in E. coli: A site-specific system isolates the ter macrodomain Modifier genes and the plasticity of genetic networks in mice Mu insertions are repaired by the double-strand break repair pathway of Escherichia coli Mutations in MITF and PAX3 cause splashed white and other white spotting phenotypes in horses PIWI associated siRNAs and piRNAs specifically require the Caenorhabditis elegans HEN1 ortholog henn-1 Patterns of Cis regulatory variation in diverse human populations Patterns of ancestry,signatures of natural selection,and genetic association with stature in Western African pygmies Polyglutamine toxicity is controlled by prion composition and gene dosage in yeast Population structure of hispanics in the United States: The multi-Ethnic study of Atherosclerosis Progressive telomere dysfunction causes cytokinesis failure and leads to the accumulation of polyploid cells Regulation of budding yeast mating-type switching donor preference by the FHA domain of Fkh1 Replication fork reversal after replication-transcription collision Runs of homozygosity implicate autozygosity as a schizophrenia risk factor SPE-44 implements sperm cell fate Sequence-specific targeting of dosage compensation in Drosophila favors an active chromatin context Sex reversal in C57BL/6J XY mice caused by increased expression of ovarian genes and insufficient activation of the testis determining pathway The DSIF subunits Spt4 and Spt5 have distinct roles at various phases of immunoglobulin class switch recombination The Rac GTP exchange factor TIAM-1 acts with CDC-42 and the guidance receptor UNC-40/DCC in neuronal protrusion and axon guidance The caenorhabditis elegans HEN1 Ortholog,HENN-1,methylates and stabilizes select subclasses of germline small RNAs The functions of mediator in Candida albicans support a role in shaping species-specific gene expression The probability of a gene tree topology within a phylogenetic network with applications to hybridization detection Transcriptional regulation of rod photoreceptor homeostasis revealed by in vivo NRL targetome analysis Type 2 diabetes risk alleles demonstrate extreme directional differentiation among human populations,compared to other diseases Whole-exome sequencing and homozygosity analysis implicate depolarization-regulated neuronal genes in autism