plos genetics سال:2010 - دوره:6

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plos genetics
سال:2010 - دوره:6 - شماره:1

A comprehensive map of insulator elements for the Drosophila genome A major role of the RecFOR pathway in DNA double-strand-break repair through ESDSA in Deinococcus radiodurans Activation of mutant enzyme function in vivo by proteasome inhibitors and treatments that induce Hsp70 Altered gene expression and DNA damage in peripheral blood cells from Friedreich's ataxia patients: Cellular model of pathology Alternative epigenetic chromatin states of polycomb target genes BRIT1/MCPH1 is essential for mitotic and meiotic recombination DNA repair and maintaining genomic stability in mice Co-orientation of replication and transcription preserves genome integrity Collaborative action of Brca1 and CtIP in elimination of covalent modifications from double-strand breaks to facilitate subsequent break repair DEP and AFO regulate reproductive habit in rice Differential localization and independent acquisition of the H3K9me2 and H3K9me3 chromatin modifications in the Caenorhabditis elegans adult germ line Distinct type of transmission barrier revealed by study of multiple prion determinants of Rnq1 Elevated levels of the polo kinase Cdc5 override the Mec1/ATR checkpoint in budding yeast by acting at different steps of the signaling pathway Environmental and genetic determinants of colony morphology in yeast Evidence for pervasive adaptive protein evolution in wild mice Evolutionary mirages: Selection on binding site composition creates the illusion of conserved grammars in Drosophila enhancers Genetic crossovers are predicted accurately by the computed human recombination map Genetic dissection of differential signaling threshold requirements for the Wnt/β-catenin pathway in vivo Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis Genotype and gene expression associations with immune function in Drosophila Inverse correlation between promoter strength and excision activity in class 1 integrons Irradiation-induced Deinococcus radiodurans genome fragmentation triggers transposition of a single resident insertion sequence Kidney development in the absence of Gdnf and Spry1 requires Fgf10 Maternal ethanol consumption alters the epigenotype and the phenotype of offspring in a mouse model Mis-spliced transcripts of nicotinic acetylcholine receptor α6 are associated with field evolved spinosad resistance in Plutella xylostella (L.) Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels Non-coding changes cause sex-specific wing size differences between closely related species of Nasonia Nonsense-mediated decay enables intron gain in Drosophila Postnatal survival of mice with maternal duplication of distal chromosome 7 induced by a Igf2/H19 imprinting control region lacking insulator function Rising from the ashes: DNA repair in Deinococcus radiodurans The Caenorhabditis elegans Werner syndrome protein functions upstream of ATR and ATM in response to DNA replication inhibition and double-strand DNA breaks The Caenorhabditis elegans elongator complex regulates neuronal α-tubulin acetylation The MCM-binding protein ETG1 aids sister chromatid cohesion required for postreplicative homologous recombination repair The gift of observation: An interview with Mary Lyon The systemic imprint of growth and its uses in ecological (meta)genomics U87MG decoded: The genomic sequence of a cytogenetically aberrant human cancer cell line Understanding gene sequence variation in the context of transcription regulation in yeast VEZF1 elements mediate protection from DNA methylation miR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway