plos pathogens سال:2017 - دوره:13

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plos pathogens
سال:2017 - دوره:13 - شماره:6

A human endogenous retrovirus-derived gene that can contribute to oncogenesis by activating the ERK pathway and inducing migration and invasion A novel genetic technique in Plasmodium berghei allows liver stage analysis of genes required for mosquito stage development and demonstrates that de novo heme synthesis is essential for liver stage development in the malaria parasite A systemic macrophage response is required to contain a peripheral poxvirus infection Aberrant plasma IL-7 and soluble IL-7 receptor levels indicate impaired T-cell response to IL-7 in human tuberculosis Acyloxyacyl hydrolase promotes the resolution of lipopolysaccharide-induced acute lung injury Alcohol-associated intestinal dysbiosis impairs pulmonary host defense against Klebsiella pneumoniae Alpha-defensin-dependent enhancement of enteric viral infection Assembly,maturation and three-dimensional helical structure of the teratogenic rubella virus Bacterial outer membrane vesicles at the plant–pathogen interface Candida albicans mannans mediate Streptococcus mutans exoenzyme GtfB binding to modulate cross-kingdom biofilm development in vivo Combined single-cell quantitation of host and SIV genes and proteins ex vivo reveals host-pathogen interactions in individual cells Competition between influenza A virus subtypes through heterosubtypic immunity modulates re-infection and antibody dynamics in the mallard duck Cooperative inhibition of RIP1-mediated NF-κB signaling by cytomegalovirus-encoded deubiquitinase and inactive homolog of cellular ribonucleotide reductase large subunit Crystal structure of Middle East respiratory syndrome coronavirus helicase Detection of a microbial metabolite by STING regulates inflammasome activation in response to Chlamydia trachomatis infection Divergent roles for Ly6C+CCR2+CX3CR1+inflammatory monocytes during primary or secondary infection of the skin with the intra-phagosomal pathogen Leishmania major Dual targeting of a virus movement protein to ER and plasma membrane subdomains is essential for plasmodesmata localization ERRα negatively regulates type I interferon induction by inhibiting TBK1-IRF3 interaction Fungal manipulation of hormone-regulated plant defense Genome-wide transposon mutagenesis of Proteus mirabilis: Essential genes,fitness factors for catheter-associated urinary tract infection,and the impact of polymicrobial infection on fitness requirements Genomic fossils reveal adaptation of non-autonomous pararetroviruses driven by concerted evolution of noncoding regulatory sequences Global sensing of the antigenic structure of herpes simplex virus gD using high-throughput array-based SPR imaging HIV-1 adaptation to NK cell-mediated immune pressure Helicobacter pylori gene silencing in vivo demonstrates urease is essential for chronic infection Host lipid droplets: An important source of lipids salvaged by the intracellular parasite Toxoplasma gondii Host-derived apolipoproteins play comparable roles with viral secretory proteins Ernsand NS1 in the infectious particle formation of Flaviviridae Human hantavirus infection elicits pronounced redistribution of mononuclear phagocytes in peripheral blood and airways Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus’s natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter Identification of C/EBPα as a novel target of the HPV8 E6 protein regulating miR-203 in human keratinocytes Identification of Interactions between Sindbis Virus Capsid Protein and Cytoplasmic vRNA as Novel Virulence Determinants Innate immunity restricts Citrobacter rodentium A/E pathogenesis initiation to an early window of opportunity Leishmania donovani resides in modified early endosomes by upregulating Rab5a expression via the downregulation of miR-494 Macrophages,but not neutrophils,are critical for proliferation of Burkholderia cenocepacia and ensuing host-damaging inflammation MicroRNAs upregulated during HIV infection target peroxisome biogenesis factors: Implications for virus biology,disease mechanisms and neuropathology Mitochondrial complex I bridges a connection between regulation of carbon flexibility and gastrointestinal commensalism in the human fungal pathogen Candida albicans MoEnd3 regulates appressorium formation and virulence through mediating endocytosis in rice blast fungus Magnaporthe oryzae Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein Mycobacterium tuberculosis subverts negative regulatory pathways in human macrophages to drive immunopathology NS5A inhibitors unmask differences in functional replicase complex half-life between different hepatitis C virus strains Oxidative stress induced in E. coli by the human antimicrobial peptide LL-37 Potassium is a key signal in host-microbiome dysbiosis in periodontitis Prions amplify through degradation of the VPS10P sorting receptor sortilin Regulated Erlin-dependent release of the B12 transmembrane J-protein promotes ER membrane penetration of a non-enveloped virus Septins restrict inflammation and protect zebrafish larvae from Shigella infection Signal transduction pathway mediated by the novel regulator LoiA for low oxygen tension induced Salmonella Typhimurium invasion Signaling C-type lectin receptors in antimycobacterial immunity Structure of the Neisseria Adhesin Complex Protein (ACP) and its role as a novel lysozyme inhibitor T3SS effector VopL inhibits the host ROS response,promoting the intracellular survival of Vibrio parahaemolyticus T6SS: The bacterial fight club in the host gut The ApaH-like phosphatase TbALPH1 is the major mRNA decapping enzyme of trypanosomes The adenovirus major core protein VII is dispensable for virion assembly but is essential for lytic infection The effector AvrRxo1 phosphorylates NAD in planta The human cytomegalovirus glycoprotein pUL11 acts via CD45 to induce T cell IL-10 secretion The microbiome in hematopoietic stem cell transplant recipients and cancer patients: Opportunities for clinical advances that reduce infection Three mutations switch H7N9 influenza to human-type receptor specificity Vibrio cholerae ensures function of host proteins required for virulence through consumption of luminal methionine sulfoxide Wolbachia elevates host methyltransferase expression to block an RNA virus early during infection