plos pathogens سال:2017 - دوره:13

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plos pathogens
سال:2017 - دوره:13 - شماره:2

A calmodulin-like protein suppresses RNA silencing and promotes geminivirus infection by degrading SGS3 via the autophagy pathway in Nicotiana benthamiana A feast for Candida: Metabolic plasticity confers an edge for virulence A high-throughput genetic screen identifies previously uncharacterized Borrelia burgdorferi genes important for resistance against reactive oxygen and nitrogen species A mouse model of paralytic myelitis caused by enterovirus D68 A positive-strand RNA virus uses alternative protein-protein interactions within a viral protease/cofactor complex to switch between RNA replication and virion morphogenesis A single mutation in the envelope protein modulates flavivirus antigenicity,stability,and pathogenesis ALPK1 controls TIFA/TRAF6-dependent innate immunity against heptose-1,7-bisphosphate of gram-negative bacteria Analysis of the T Cell Response to Zika Virus and Identification of a Novel CD8+T Cell Epitope in Immunocompetent Mice Applying antibody-sensitive hypervariable region 1-deleted hepatitis C virus to the study of escape pathways of neutralizing human monoclonal antibody AR5A Arsenite-induced stress granule formation is inhibited by elevated levels of reduced glutathione in West Nile virus-infected cells Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial CD8+T cell cytotoxicity mediates pathology in the skin by inflammasome activation and IL-1β production Comparative analysis estimates the relative frequencies of co-divergence and cross-species transmission within viral families Correction to: A Large Collection of Novel Nematode-Infecting Microsporidia and Their Diverse Interactions with Caenorhabditis elegans and Other Related Nematodes (PLOS Pathogens,(2016),12,12,(e1006093),10.1371/journal.ppat.1006093) Correction to: HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory Receptors (PLOS Pathogens,(2017),13,1,(e1006120),10.1371/journal.ppat.1006120) Correction to: Increased Abundance of M Cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility (PLOS Pathogens,(2016),12,12,(e1006075),10.1371/journal.ppat.1006075) Correction to: Influenza Virus Targets Class I MHC-Educated NK Cells for Immunoevasion (PLOS Pathogens,(2016),12,12,(e1006105),10.1371/journal.ppat.1006105) Correction to: Macrophage Colony Stimulating Factor Derived from CD4+ T Cells Contributes to Control of a Blood-Borne Infection (PLOS Pathogens,(2016),12,12,(e1006046),10.1371/journal.ppat.1006046) Correction to: Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell Communication System ComRS (PLOS Pathogens,(2016),12,12,(e1005980),10.1371/journal.ppat.1005980) Correction to: Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity (PLOS Pathogens,(2016),12,6,(e1005684),10.1371/journal.ppat.1005684) Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication Environmental pH modulation by pathogenic fungi as a strategy to conquer the host Ex vivo activation of CD4+T-cells from donors on suppressive ART can lead to sustained production of infectious HIV-1 from a subset of infected cells Extra-epitopic hepatitis C virus polymorphisms confer resistance to broadly neutralizing antibodies by modulating binding to scavenger receptor B1 Functional diversity of secreted cestode Kunitz proteins: Inhibition of serine peptidases and blockade of cation channels Hepatic deficiency of the pioneer transcription factor FoxA restricts hepatitis B virus biosynthesis by the developmental regulation of viral DNA methylation Hepatitis C virus infection inhibits a Src-kinase regulatory phosphatase and reduces T cell activation in vivo Host cell interactions of outer membrane vesicle-associated virulence factors of enterohemorrhagic Escherichia coli O157: Intracellular delivery,trafficking and mechanisms of cell injury Identification of cyst nematode B-type CLE peptides and modulation of the vascular stem cell pathway for feeding cell formation Identification of several high-risk HPV inhibitors and drug targets with a novel high-throughput screening assay Immune-driven alterations in mucin sulphation is an important mediator of Trichuris muris helminth expulsion Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells Multi-layered control of Galectin-8 mediated autophagy during adenovirus cell entry through a conserved PPxY motif in the viral capsid Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFκΒ signaling by stabilizing IκBα Nematode neuropeptides as transgenic nematicides New Paradigms to Help Solve the Global Aquaculture Disease Crisis OSBPL10,RXRA and lipid metabolism confer African-ancestry protection against dengue haemorrhagic fever in admixed CUBANS Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function RNA-Seq analysis of chikungunya virus infection and identification of granzyme A as a major promoter of arthritic inflammation Release of HIV-1 sequestered in the vesicles of oral and genital mucosal epithelial cells by epithelial-lymphocyte interaction Replication of CMV in the gut of HIV-infected individuals and epithelial barrier dysfunction Resolving host–pathogen interactions by dual RNA-seq Role of Arf GTPases in fungal morphogenesis and virulence SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy Selective expansion of high functional avidity memory CD8 T cell clonotypes during hepatitis C virus reinfection and clearance Structure of a pentameric virion-associated fiber with a potential role in Orsay virus entry to host cells Substrate-analogous inhibitors exert antimalarial action by targeting the Plasmodium lactate transporter PfFNT at nanomolar scale The Malaria Parasite's Lactate Transporter PfFNT Is the Target of Antiplasmodial Compounds Identified in Whole Cell Phenotypic Screens The effective rate of influenza reassortment is limited during human infection The morphogenesis-related NDR kinase pathway of Colletotrichum orbiculare is required for translating plant surface signals into infection-related morphogenesis and pathogenesis The thermodynamics of Pr55Gag-RNA interaction regulate the assembly of HIV The transcriptome of HIV-1 infected intestinal CD4+ T cells exposed to enteric bacteria They Might Be Giants: Does Syncytium Formation Sink or Spread HIV Infection? Toxin Mediates Sepsis Caused by Methicillin-Resistant Staphylococcus epidermidis Zika Virus Antagonizes Type I Interferon Responses during Infection of Human Dendritic Cells