plos pathogens سال:2011 - دوره:7

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plos pathogens
سال:2011 - دوره:7 - شماره:6

A dynamic landscape for antibody binding modulates antibody-mediated neutralization of West Nile virus A freeze frame view of vesicular stomatitis virus transcription defines a minimal length of RNA for 5′ processing A role for TLR4 in clostridium difficile infection and the recognition of surface layer proteins Bacteria-induced Dscam isoforms of the crustacean,Pacifastacus leniusculus Candida albicans infection of caenorhabditis elegans induces antifungal immune defenses Clathrin facilitates the morphogenesis of retrovirus particles Compensatory T cell responses in IRG-deficient mice prevent sustained Chlamydia trachomatis infections Contribution of intrinsic reactivity of the HIV-1 envelope glycoproteins to CD4-independent infection and global inhibitor sensitivity Coronavirus gene 7 counteracts host defenses and modulates virus virulence Cross-neutralizing antibodies to pandemic 2009 H1N1 and recent seasonal H1N1 influenza a strains influenced by a mutation in hemagglutinin subunit 2 Cyclic di-gmp is essential for the survival of the lyme disease spirochete in ticks Detection of inferred CCR5- and CXCR4-using HIV-1 variants and evolutionary intermediates using ultra-deep pyrosequencing Endemic dengue associated with the co-circulation of multiple viral lineages and localized density-dependent transmission Environmental constraints guide migration of malaria parasites during transmission Evolutionary analysis of inter-farm transmission dynamics in a highly pathogenic avian influenza epidemic Functional analysis of host factors that mediate the intracellular lifestyle of cryptococcus neoformans Glycosaminoglycan binding facilitates entry of a bacterial pathogen into central nervous systems HIV-1 efficient entry in inner foreskin is mediated by elevated CCL5/RANTES that recruits T cells and fuels conjugate formation with Langerhans cells HIV/SIV infection primes monocytes and dendritic cells for apoptosis HSV-2 infection of dendritic cells amplifies a highly susceptible HIV-1 cell target High affinity nanobodies against the trypanosome brucei VSG are potent trypanolytic agents that block endocytosis Highly pathogenic avian influenza virus H5N1 infects alveolar macrophages without virus production or excessive TNF-alpha induction Identification of DNA-damage DNA-binding protein 1 as a conditional essential factor for cytomegalovirus replication in interferon-γ-stimulated cells Impact of endofungal bacteria on infection biology,food safety,and drug development Induction of noxa-mediated apoptosis by modified vaccinia virus ankara depends on viral recognition by cytosolic helicases,leading to IRF-3/IFN-β-dependent induction of pro-apoptotic noxa Insertion of an esterase gene into a specific locust pathogen (Metarhizium acridum) enables it to infect caterpillars Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis Low CCR7-mediated migration of human monocyte derived dendritic cells in response to human respiratory syncytial virus and human metapneumovirus Molecular interactions that enable movement of the lyme disease agent from the tick gut into the hemolymph Mycobacterium tuberculosis uses host triacylglycerol to accumulate lipid droplets and acquires a dormancy-like phenotype in lipid-loaded macrophages Passively administered pooled human immunoglobulins exert il-10 dependent anti-inflammatory effects that protect against fatal HSV encephalitis Pathogen recognition receptor signaling accelerates phosphorylation-dependent degradation of IFNAR1 Plasmodium falciparum merozoite invasion is inhibited by antibodies that target the PfRH2a and b binding domains Productive parvovirus B19 infection of primary human erythroid progenitor cells at hypoxia is regulated by STAT5A and MEK signaling but not HIFα Spatial dynamics of human-origin H1 influenza a virus in north american swine Sporangiospore size dimorphism is linked to virulence of mucor circinelloides Structural and mechanistic studies of measles virus illuminate paramyxovirus entry T. brucei infection reduces B lymphopoiesis in bone marrow and truncates compensatory splenic lymphopoiesis through transitional B-cell apoptosis The N-Terminus of the RNA polymerase from infectious pancreatic necrosis virus is the determinant of genome attachment The SV40 late protein VP4 is a viroporin that forms pores to disrupt membranes for viral release The binding of triclosan to SmeT,the repressor of the multidrug efflux pump smeDEF,induces antibiotic resistance in Stenotrophomonas maltophilia The influenza virus protein PB1-F2 inhibits the induction of type i interferon at the level of the MAVS adaptor protein The intrinsic antiviral defense to incoming HSV-1 genomes includes specific DNA repair proteins and is counteracted by the viral protein ICP0 The lipid transfer protein CERT interacts with the Chlamydia inclusion protein IncD and participates to ER-Chlamydia inclusion membrane contact sites The n-glycan glycoprotein deglycosylation complex (gpd) from capnocytophaga canimorsus deglycosylates human igg Tipping the balance: Sclerotinia sclerotiorum secreted oxalic acid suppresses host defenses by manipulating the host redox environment rational vaccine design for HIV should take into account the adaptive potential of polyreactive antibodies