plos pathogens سال:2012 - دوره:8

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plos pathogens
سال:2012 - دوره:8 - شماره:1

(Homo)glutathione deficiency impairs root-knot nematode development in Medicago truncatula Antibody inhibition of a viral type 1 interferon decoy receptor cures a viral disease by restoring interferon signaling in the liver Development of functional and molecular correlates of vaccine-induced protection for a model intracellular pathogen,F. tularensis LVS HCMV targets the metabolic stress response through activation of AMPK whose activity is important for viral replication Historical contingencies modulate the adaptability of rice yellow mottle virus How do bacteria know they are on a surface and regulate their response to an adhering state? How humane is your endpoint?-refining the science-driven approach for termination of animal studies of chronic infection Human herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma Human subtilase SKI-1/S1P is a master regulator of the HCV lifecycle and a potential host cell target for developing indirect-acting antiviral agents Human-like PB2 627K influenza virus polymerase activity is regulated by importin-α1 and -α7 IL-10R blockade during chronic schistosomiasis mansoni results in the loss of B cells from the liver and the development of severe pulmonary disease Identification and in vitro analysis of the GatD/MurT enzyme-complex catalyzing lipid II amidation in Staphylococcus aureus Identification of genetic determinants and enzymes involved with the amidation of glutamic acid residues in the peptidoglycan of Staphylococcus aureus Impaired chromatin remodelling at STAT1-regulated promoters leads to global unresponsiveness of Toxoplasma gondii-infected macrophages to IFN-γ Insights into minor group rhinovirus uncoating: The X-ray structure of the HRV2 empty capsid Legionella pneumophila secretes a mitochondrial carrier protein during infection Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy Mechanisms of NK cell-macrophage Bacillus anthracis crosstalk: A balance between stimulation by spores and differential disruption by toxins Molecular determinants and dynamics of hepatitis C virus secretion Nonsex genes in the mating type locus of Candida albicans play roles in a/α biofilm formation,including impermeability and fluconazole resistance Production of virus-derived ping-pong-dependent piRNA-like small RNAs in the mosquito soma Progressive visceral leishmaniasis is driven by dominant parasite-induced STAT6 activation and STAT6-dependent host arginase 1 expression Replication in cells of hematopoietic origin is necessary for dengue virus dissemination Sequence divergent RXLR effectors share a structural fold conserved across plant pathogenic oomycete species Sexual development in plasmodium: Lessons from functional analyses Slit2/Robo4 signaling modulates HIV-1 gp120-induced lymphatic hyperpermeability Systems biology approaches reveal a specific interferon-inducible signature in HTLV-1 associated myelopathy Temporal expression of bacterial proteins instructs host CD4 T cell expansion and Th17 development The RBP-Jκ binding sites within the RTA promoter regulate KSHV latent infection and cell proliferation The Vibrio cholerae colonization factor GbpA possesses a modular structure that governs binding to different host surfaces The bZIP transcription factor Rca1p is a central regulator of a novel CO 2 sensing pathway in yeast The bacterial cytoskeleton modulates motility,type 3 secretion,and colonization in Salmonella The circadian clock protein timeless regulates phagocytosis of bacteria in Drosophila The cysteine rich necrotrophic effector SnTox1 produced by Stagonospora nodorum triggers susceptibility of wheat lines harboring Snn1 The intracellular DNA sensor IFI16 gene acts as restriction factor for human Cytomegalovirus replication The murine coronavirus hemagglutinin-esterase receptor-binding site: A major shift in ligand specificity through modest changes in architecture The viral and cellular microRNA targetome in lymphoblastoid cell lines Trypanosoma cruzi trans-sialidase in complex with a neutralizing antibody: Structure/function studies towards the rational design of inhibitors Two distinct coagulase-dependent barriers protect Staphylococcus aureus from neutrophils in a three dimensional in vitro infection model Two genetic determinants acquired late in Mus evolution regulate the inclusion of exon 5,which alters mouse APOBEC3 translation efficiency Two-drug antimicrobial chemotherapy: A mathematical model and experiments with Mycobacterium marinum Type 1 interferons and antiviral CD8 T-Cell responses Zebrafish: A see-through host and a fluorescent toolbox to probe host-pathogen interaction