plos genetics سال:2016 - دوره:12

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plos genetics
سال:2016 - دوره:12 - شماره:2

3’UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells A Mutation in PMP2 Causes Dominant Demyelinating Charcot-Marie-Tooth Neuropathy A Novel Epigenetic Silencing Pathway Involving the Highly Conserved 5’-3’ Exoribonuclease Dhp1/Rat1/Xrn2 in Schizosaccharomyces pombe A Parent-of-Origin Effect Impacts the Phenotype in Low Penetrance Retinoblastoma Families Segregating the c.1981C>T/p.Arg661Trp Mutation of RB1 A Point Mutation in p190A RhoGAP Affects Ciliogenesis and Leads to Glomerulocystic Kidney Defects A RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells A Screen for Modifiers of Cilia Phenotypes Reveals Novel MKS Alleles and Uncovers a Specific Genetic Interaction between osm-3 and nphp-4 Adaptive Remodeling of the Bacterial Proteome by Specific Ribosomal Modification Regulates Pseudomonas Infection and Niche Colonisation An Energy-Independent Pro-longevity Function of Triacylglycerol in Yeast Angiotensin Converting Enzyme (ACE) Inhibitor Extends Caenorhabditis elegans Life Span Arabidopsis WRKY6 Transcription Factor Acts as a Positive Regulator of Abscisic Acid Signaling during Seed Germination and Early Seedling Development Bovine Host Genetic Variation Influences Rumen Microbial Methane Production with Best Selection Criterion for Low Methane Emitting and Efficiently Feed Converting Hosts Based on Metagenomic Gene Abundance C-terminal Src Kinase Gates Homeostatic Synaptic Plasticity and Regulates Fasciclin II Expression at the Drosophila Neuromuscular Junction Carriage of λ Latent Virus Is Costly for Its Bacterial Host due to Frequent Reactivation in Monoxenic Mouse Intestine Continuous Influx of Genetic Material from Host to Virus Populations DAF-16 and TCER-1 Facilitate Adaptation to Germline Loss by Restoring Lipid Homeostasis and Repressing Reproductive Physiology in C. elegans DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia Determinants of Chromosome Architecture: Insulator Pairing in cis and in trans EEPD1: Breaking and Rescuing the Replication Fork Embryonic Stem Cell (ES)-Specific Enhancers Specify the Expression Potential of ES Genes in Cancer Exome Sequencing of Uterine Leiomyosarcomas Identifies Frequent Mutations in TP53,ATRX,and MED12 Extensive Recombination of a Yeast Diploid Hybrid through Meiotic Reversion Four and a Half LIM Domains 1b (Fhl1b) Is Essential for Regulating the Liver versus Pancreas Fate Decision and for β-Cell Regeneration G = E: What GWAS Can Tell Us about the Environment GBStools: A Statistical Method for Estimating Allelic Dropout in Reduced Representation Sequencing Data Genome-Wide and Experimental Resolution of Relative Translation Elongation Speed at Individual Gene Level in Human Cells Genomics of Rapid Incipient Speciation in Sympatric Threespine Stickleback Graded Proteasome Dysfunction in Caenorhabditis elegans Activates an Adaptive Response Involving the Conserved SKN-1 and ELT-2 Transcription Factors and the Autophagy-Lysosome Pathway Hydrophobic Core Variations Provide a Structural Framework for Tyrosine Kinase Evolution and Functional Specialization Identification of Novel Candidate Genes for Early-Onset Colorectal Cancer Susceptibility Ingression Progression Complexes Control Extracellular Matrix Remodelling during Cytokinesis in Budding Yeast Intact Cohesion,Anaphase,and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2 Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution Iterative Usage of Fixed and Random Effect Models for Powerful and Efficient Genome-Wide Association Studies Liver-Enriched Gene 1,a Glycosylated Secretory Protein,Binds to FGFR and Mediates an Anti-stress Pathway to Protect Liver Development in Zebrafish MEF2C and EBF1 Co-regulate B Cell-Specific Transcription Maintenance of Tissue Pluripotency by Epigenetic Factors Acting at Multiple Levels Mps1Mph1 Kinase Phosphorylates Mad3 to Inhibit Cdc20Slp1-APC/C and Maintain Spindle Checkpoint Arrests NPAS2 Compensates for Loss of CLOCK in Peripheral Circadian Oscillators Nucleolar DEAD-Box RNA Helicase TOGR1 Regulates Thermotolerant Growth as a Pre-rRNA Chaperone in Rice PLOS Genetics 2015 Reviewer Thank You Pedigree- and SNP-Associated Genetics and Recent Environment are the Major Contributors to Anthropometric and Cardiometabolic Trait Variation Rab6 Is Required for Multiple Apical Transport Pathways but Not the Basolateral Transport Pathway in Drosophila Photoreceptors RecG Directs DNA Synthesis during Double-Strand Break Repair Reciprocal Effects on Neurocognitive and Metabolic Phenotypes in Mouse Models of 16p11.2 Deletion and Duplication Syndromes Regulation of Stem Cell Proliferation and Cell Fate Specification by Wingless/Wnt Signaling Gradients Enriched at Adult Intestinal Compartment Boundaries Repeat-Associated Fission Yeast-Like Regional Centromeres in the Ascomycetous Budding Yeast Candida tropicalis SPARC Promotes Cell Invasion In Vivo by Decreasing Type IV Collagen Levels in the Basement Membrane Six Novel Loci Associated with Circulating VEGF Levels Identified by a Meta-analysis of Genome-Wide Association Studies Strong Components of Epigenetic Memory in Cultured Human Fibroblasts Related to Site of Origin and Donor Age Strong Selection at MHC in Mexicans since Admixture Synergistic Control of Kinetochore Protein Levels by Psh1 and Ubr2 Systems Level Analyses Reveal Multiple Regulatory Activities of CodY Controlling Metabolism,Motility and Virulence in Listeria monocytogenes TDM1 Regulation Determines the Number of Meiotic Divisions Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs The BBSome Controls Energy Homeostasis by Mediating the Transport of the Leptin Receptor to the Plasma Membrane The Epigenomic Landscape of Prokaryotes The Interplay between Myc and CTP Synthase in Drosophila The Quantitative Basis of the Arabidopsis Innate Immune System to Endemic Pathogens Depends on Pathogen Genetics The Replisome-Coupled E3 Ubiquitin Ligase Rtt101Mms22 Counteracts Mrc1 Function to Tolerate Genotoxic Stress The Zinc-Finger Protein SOP1 Is Required for a Subset of the Nuclear Exosome Functions in Arabidopsis Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression Weak Epistasis Generally Stabilizes Phenotypes in a Mouse Intercross Which Genetics Variants in DNase-Seq Footprints Are More Likely to Alter Binding?