plos genetics سال:2016 - دوره:12

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plos genetics
سال:2016 - دوره:12 - شماره:7

A Cascade of Wnt,Eda,and Shh Signaling Is Essential for Touch Dome Merkel Cell Development A High Temperature-Dependent Mitochondrial Lipase EXTRA GLUME1 Promotes Floral Phenotypic Robustness against Temperature Fluctuation in Rice (Oryza sativa L.) A MutSβ-Dependent Contribution of MutSα to Repeat Expansions in Fragile X Premutation Mice? A Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to Neuroinflammation Absence of the ER Cation Channel TMEM38B/TRIC-B Disrupts Intracellular Calcium Homeostasis and Dysregulates Collagen Synthesis in Recessive Osteogenesis Imperfecta Arabidopsis COG Complex Subunits COG3 and COG8 Modulate Golgi Morphology,Vesicle Trafficking Homeostasis and Are Essential for Pollen Tube Growth Aversive Behavior in the Nematode C. elegans Is Modulated by cGMP and a Neuronal Gap Junction Network Chemogenetic E-MAP in Saccharomyces cerevisiae for Identification of Membrane Transporters Operating Lipid Flip Flop Complex Ancestries of Lager-Brewing Hybrids Were Shaped by Standing Variation in the Wild Yeast Saccharomyces eubayanus Conservation of Distinct Genetically-Mediated Human Cortical Pattern Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression,Vascular Cell Survival,Atherosclerotic Plaque Stability and Risk of Myocardial Infarction DLK-1,SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegans Dnmt3a Regulates Proliferation of Muscle Satellite Cells via p57Kip2 Dynamics of Chloroplast Translation during Chloroplast Differentiation in Maize Expansion of GA Dinucleotide Repeats Increases the Density of CLAMP Binding Sites on the X-Chromosome to Promote Drosophila Dosage Compensation Exposure to the BPA-Substitute Bisphenol S Causes Unique Alterations of Germline Function Expression Quantitative Trait Locus Mapping Studies in Mid-secretory Phase Endometrial Cells Identifies HLA-F and TAP2 as Fecundability-Associated Genes FACT Assists Base Excision Repair by Boosting the Remodeling Activity of RSC Formation of a Polycomb-Domain in the Absence of Strong Polycomb Response Elements Fragment Length of Circulating Tumor DNA Functional Crosstalk between the PP2A and SUMO Pathways Revealed by Analysis of STUbL Suppressor,razor 1-1 Functional Dissection of the Blocking and Bypass Activities of the Fab-8 Boundary in the Drosophila Bithorax Complex Gene Regulation in Developing Chloroplasts Disentangled Gene-Environment Interactions in Stress Response Contribute Additively to a Genotype-Environment Interaction Genetic Dissection of Cardiac Remodeling in an Isoproterenol-Induced Heart Failure Mouse Model Host-Pathogen Coevolution and the Emergence of Broadly Neutralizing Antibodies in Chronic Infections Intestinal Autophagy Improves Healthspan and Longevity in C. elegans during Dietary Restriction Intra-patient Inter-metastatic Genetic Heterogeneity in Colorectal Cancer as a Key Determinant of Survival after Curative Liver Resection Levels of Ycg1 Limit Condensin Function during the Cell Cycle Limited Contribution of DNA Methylation Variation to Expression Regulation in Arabidopsis thaliana Multiple Rad52-Mediated Homology-Directed Repair Mechanisms Are Required to Prevent Telomere Attrition-Induced Senescence in Saccharomyces cerevisiae Mutation of Growth Arrest Specific 8 Reveals a Role in Motile Cilia Function and Human Disease Next-Generation “-omics” Approaches Reveal a Massive Alteration of Host RNA Metabolism during Bacteriophage Infection of Pseudomonas aeruginosa Orderly Replication and Segregation of the Four Replicons of Burkholderia cenocepacia J2315 Overexpression of Mitochondria Mediator Gene TRIAP1 by miR-320b Loss Is Associated with Progression in Nasopharyngeal Carcinoma Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development Prefoldin Promotes Proteasomal Degradation of Cytosolic Proteins with Missense Mutations by Maintaining Substrate Solubility R7 Photoreceptor Specification in the Developing Drosophila Eye: The Role of the Transcription Factor Deadpan Receptor-Like Kinase RUPO Interacts with Potassium Transporters to Regulate Pollen Tube Growth and Integrity in Rice Recombination Rate Heterogeneity within Arabidopsis Disease Resistance Genes Regulation of Aerobic Energy Metabolism in Podospora anserina by Two Paralogous Genes Encoding Structurally Different c-Subunits of ATP Synthase Regulation of the BMP Signaling-Responsive Transcriptional Network in the Drosophila Embryo Secretion of Rhoptry and Dense Granule Effector Proteins by Nonreplicating Toxoplasma gondii Uracil Auxotrophs Controls the Development of Antitumor Immunity Selection on Network Dynamics Drives Differential Rates of Protein Domain Evolution Selection on a Subunit of the NURF Chromatin Remodeler Modifies Life History Traits in a Domesticated Strain of Caenorhabditis elegans Srs2 and Mus81–Mms4 Prevent Accumulation of Toxic Inter-Homolog Recombination Intermediates Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress,Sleep,and Huntington’s Disease Telomere Length and the Cancer–Atherosclerosis Trade-Off Temporal Shift of Circadian-Mediated Gene Expression and Carbon Fixation Contributes to Biomass Heterosis in Maize Hybrids The Arabidopsis KINβγ Subunit of the SnRK1 Complex Regulates Pollen Hydration on the Stigma by Mediating the Level of Reactive Oxygen Species in Pollen The CaM Kinase CMK-1 Mediates a Negative Feedback Mechanism Coupling the C. elegans Glutamate Receptor GLR-1 with Its Own Transcription The Calponin Family Member CHDP-1 Interacts with Rac/CED-10 to Promote Cell Protrusions The Landscape of A-to-I RNA Editome Is Shaped by Both Positive and Purifying Selection The Molecular Mechanism of Ethylene-Mediated Root Hair Development Induced by Phosphate Starvation The Replication of Frataxin Gene Is Assured by Activation of Dormant Origins in the Presence of a GAA-Repeat Expansion The Roles of RNA Polymerase I and III Subunits Polr1c and Polr1d in Craniofacial Development and in Zebrafish Models of Treacher Collins Syndrome Timely Endocytosis of Cytokinetic Enzymes Prevents Premature Spindle Breakage during Mitotic Exit Tracking the Fragile X Mental Retardation Protein in a Highly Ordered Neuronal RiboNucleoParticles Population: A Link between Stalled Polyribosomes and RNA Granules Two-Step Regulation of a Meristematic Cell Population Acting in Shoot Branching in Arabidopsis What Is a Genome? Who Watches the Watchmen: Roles of RNA Modifications in the RNA Interference Pathway Whole Genome Sequencing Identifies a 78 kb Insertion from Chromosome 8 as the Cause of Charcot-Marie-Tooth Neuropathy CMTX3 XRN2 Links Transcription Termination to DNA Damage and Replication Stress dachshund Potentiates Hedgehog Signaling during Drosophila Retinogenesis