plos genetics سال:2016 - دوره:12

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plos genetics
سال:2016 - دوره:12 - شماره:10

53BP1 Protects against CtIP-Dependent Capture of Ectopic Chromosomal Sequences at the Junction of Distant Double-Strand Breaks - صفحه:e1006230- A Large Genome-Wide Association Study of Age-Related Hearing Impairment Using Electronic Health Records A Multistate Toggle Switch Defines Fungal Cell Fates and Is Regulated by Synergistic Genetic Cues A New Membrane Protein Sbg1 Links the Contractile Ring Apparatus and Septum Synthesis Machinery in Fission Yeast Alignment of Homologous Chromosomes and Effective Repair of Programmed DNA Double-Strand Breaks during Mouse Meiosis Require the Minichromosome Maintenance Domain Containing 2 (MCMDC2) Protein Amplification of TLO Mediator Subunit Genes Facilitate Filamentous Growth in Candida Spp. CERAMIC: Case-Control Association Testing in Samples with Related Individuals,Based on Retrospective Mixed Model Analysis with Adjustment for Covariates Chromosomal Replication Complexity: A Novel DNA Metrics and Genome Instability Factor Combined Use of Genome-Wide Association Data and Correlation Networks Unravels Key Regulators of Primary Metabolism in Arabidopsis thaliana Coordinately Co-opted Multiple Transposable Elements Constitute an Enhancer for wnt5a Expression in the Mammalian Secondary Palate Dbo/Henji Modulates Synaptic dPAK to Gate Glutamate Receptor Abundance and Postsynaptic Response Directed Evolution Reveals Unexpected Epistatic Interactions That Alter Metabolic Regulation and Enable Anaerobic Xylose Use by Saccharomyces cerevisiae Distinct Roles of Meiosis-Specific Cohesin Complexes in Mammalian Spermatogenesis Dom34 Links Translation to Protein O-mannosylation Dual Role of a SAS10/C1D Family Protein in Ribosomal RNA Gene Expression and Processing Is Essential for Reproduction in Arabidopsis thaliana Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study Epigenetics in Cancer: A Hematological Perspective Family Based Whole Exome Sequencing Reveals the Multifaceted Role of Notch Signaling in Congenital Heart Disease Fine Mapping of a Dravet Syndrome Modifier Locus on Mouse Chromosome 5 and Candidate Gene Analysis by RNA-Seq Functional Trade-Offs in Promiscuous Enzymes Cannot Be Explained by Intrinsic Mutational Robustness of the Native Activity Genetic Analysis of Collective Motility of Paenibacillus sp. NAIST15-1 Genetic Dissection of Aversive Associative Olfactory Learning and Memory in Drosophila Larvae Genetic Evidence for Elevated Pathogenicity of Mitochondrial DNA Heteroplasmy in Autism Spectrum Disorder Genome-Wide Interaction Analyses between Genetic Variants and Alcohol Consumption and Smoking for Risk of Colorectal Cancer Genomic Scars Generated by Polymerase Theta Reveal the Versatile Mechanism of Alternative End-Joining High-Throughput Identification of Adaptive Mutations in Experimentally Evolved Yeast Populations Local Adaptation of Sun-Exposure-Dependent Gene Expression Regulation in Human Skin Local Transcriptional Control of YUCCA Regulates Auxin Promoted Root-Growth Inhibition in Response to Aluminium Stress in Arabidopsis Maintenance of Xist Imprinting Depends on Chromatin Condensation State and Rnf12 Dosage in Mice Maternal Diet and Insulin-Like Signaling Control Intergenerational Plasticity of Progeny Size and Starvation Resistance Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis Metatranscriptomic Study of Common and Host-Specific Patterns of Gene Expression between Pines and Their Symbiotic Ectomycorrhizal Fungi in the Genus Suillus MiR-155 Enhances Insulin Sensitivity by Coordinated Regulation of Multiple Genes in Mice Multiple Pairwise Analysis of Non-homologous Centromere Coupling Reveals Preferential Chromosome Size-Dependent Interactions and a Role for Bouquet Formation in Establishing the Interaction Pattern Multisite Phosphorylation of NuMA-Related LIN-5 Controls Mitotic Spindle Positioning in C. elegans Mutations in TSPEAR,Encoding a Regulator of Notch Signaling,Affect Tooth and Hair Follicle Morphogenesis Neuropsin Inactivation Has Protective Effects against Depressive-Like Behaviours and Memory Impairment Induced by Chronic Stress No Reliable Association between Runs of Homozygosity and Schizophrenia in a Well-Powered Replication Study Novel Genetic Variants for Cartilage Thickness and Hip Osteoarthritis Of Rings and Rods: Regulating Cohesin Entrapment of DNA to Generate Intra- and Intermolecular Tethers Ontogeny of Unstable Chromosomes Generated by Telomere Error in Budding Yeast PHACTR1 Is a Genetic Susceptibility Locus for Fibromuscular Dysplasia Supporting Its Complex Genetic Pattern of Inheritance Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease Regulation of Dense-Core Granule Replenishment by Autocrine BMP Signalling in Drosophila Secondary Cells Round Spermatid Injection Rescues Female Lethality of a Paternally Inherited Xist Deletion in Mouse Secretion-Positive LGI1 Mutations Linked to Lateral Temporal Epilepsy Impair Binding to ADAM22 and ADAM23 Receptors Signaling through Lrg1,Rho1 and Pkc1 Governs Candida albicans Morphogenesis in Response to Diverse Cues Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate TCS1,a Microtubule-Binding Protein,Interacts with KCBP/ZWICHEL to Regulate Trichome Cell Shape in Arabidopsis thaliana The Diguanylate Cyclase HsbD Intersects with the HptB Regulatory Cascade to Control Pseudomonas aeruginosa Biofilm and Motility The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts The QTL GNP1 Encodes GA20ox1,Which Increases Grain Number and Yield by Increasing Cytokinin Activity in Rice Panicle Meristems The RTR Complex Partner RMI2 and the DNA Helicase RTEL1 Are Both Independently Involved in Preserving the Stability of 45S rDNA Repeats in Arabidopsis thaliana The Skp1 Homologs SKR-1/2 Are Required for the Caenorhabditis elegans SKN-1 Antioxidant/Detoxification Response Independently of p38 MAPK The Sweet Potato NAC-Domain Transcription Factor IbNAC1 Is Dynamically Coordinated by the Activator IbbHLH3 and the Repressor IbbHLH4 to Reprogram the Defense Mechanism against Wounding Vimar Is a Novel Regulator of Mitochondrial Fission through Miro Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival Zasp52,a Core Z-disc Protein in Drosophila Indirect Flight Muscles,Interacts with α-Actinin via an Extended PDZ Domain Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function Zinc Transporter SLC39A7/ZIP7 Promotes Intestinal Epithelial Self-Renewal by Resolving ER Stress