plos genetics سال:2017 - دوره:13

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plos genetics
سال:2017 - دوره:13 - شماره:6

A chromosome 5q31.1 locus associates with tuberculin skin test reactivity in HIV-positive individuals from tuberculosis hyper-endemic regions in east Africa A conserved mitochondrial surveillance pathway is required for defense against Pseudomonas aeruginosa A conserved role for the ESCRT membrane budding complex in LINE retrotransposition A genetic framework controlling the differentiation of intestinal stem cells during regeneration in Drosophila A highly specific phage defense system is a conserved feature of the Vibrio cholerae mobilome Allelic variants of OsHKT1;1 underlie the divergence between indica and japonica subspecies of rice (Oryza sativa) for root sodium content An autonomous metabolic role for Spen Analysis of DNA polymerase ν function in meiotic recombination,immunoglobulin class-switching,and DNA damage tolerance Cleavage of the SUN-domain protein Mps3 at its N-terminus regulates centrosome disjunction in budding yeast meiosis Differential regulation of polarized synaptic vesicle trafficking and synapse stability in neural circuit rewiring in Caenorhabditis elegans Distinguishing functional polymorphism from random variation in the sequences of >10,000 HLA-A,-B and -C alleles Dynamics and impact of homologous recombination on the evolution of Legionella pneumophila Dynamics of DNA methylomes underlie oyster development Flipping chromosomes in deep-sea archaea Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy Genetic,structural,and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis Genomic introgression mapping of field-derived multiple-anthelmintic resistance in Teladorsagia circumcincta Hybridization and polyploidy enable genomic plasticity without sex in the most devastating plant-parasitic nematodes Identification of Padi2 as a novel angiogenesis-regulating gene by genome association studies in mice Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching,protein expression,and responsiveness to type I interferons Integrative analysis of genomic alterations in triple-negative breast cancer in association with homologous recombination deficiency Joint modeling of genetically correlated diseases and functional annotations increases accuracy of polygenic risk prediction Lack of a peroxiredoxin suppresses the lethality of cells devoid of electron donors by channelling electrons to oxidized ribonucleotide reductase Lokiarchaea are close relatives of Euryarchaeota,not bridging the gap between prokaryotes and eukaryotes Novel interplay between JNK and Egfr signaling in Drosophila dorsal closure One ligand,two regulators and three binding sites: How KDPG controls primary carbon metabolism in Pseudomonas Optimal sequencing strategies for identifying disease-associated singletons Peroxisomal biogenesis is genetically and biochemically linked to carbohydrate metabolism in Drosophila and mouse Pervasive antagonistic interactions among hybrid incompatibility loci Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions Ribosomal DNA copy number loss and sequence variation in cancer Spatio-temporal orientation of microtubules controls conical cell shape in Arabidopsis thaliana petals Splicing stimulates siRNA formation at Drosophila DNA double-strand breaks TCP4-dependent induction of CONSTANS transcription requires GIGANTEA in photoperiodic flowering in Arabidopsis The Arabidopsis leucine-rich repeat receptor kinase MIK2/LRR-KISS connects cell wall integrity sensing,root growth and response to abiotic and biotic stresses The yeast protein kinase Sch9 adjusts V-ATPase assembly/disassembly to control pH homeostasis and longevity in response to glucose availability Time dependent genetic analysis links field and controlled environment phenotypes in the model C4grass Setaria Transcription coactivator and lncRNA duet evoke Hox genes Transcriptomes of six mutants in the Sen1 pathway reveal combinatorial control of transcription termination across the Saccharomyces cerevisiae genome p53 and TAp63 participate in the recombination-dependent pachytene arrest in mouse spermatocytes p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate