plos genetics سال:2017 - دوره:13

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plos genetics
سال:2017 - دوره:13 - شماره:7

A Hox complex activates and potentiates the Epidermal Growth Factor signaling pathway to specify Drosophila oenocytes A drosophila model for toxicogenomics: Genetic variation in susceptibility to heavy metal exposure A unique enhancer boundary complex on the mouse ribosomal RNA genes persists after loss of Rrn3 or UBF and the inactivation of RNA polymerase I transcription African genetic ancestry interacts with body mass index to modify risk for uterine fibroids Altered paracellular cation permeability due to a rare CLDN10B variant causes anhidrosis and kidney damage An ancient neurotrophin receptor code; a single Runx/Cbfβ complex determines somatosensory neuron fate specification in zebrafish Bidirectional interplay of HSF1 degradation and UPR activation promotes tau hyperphosphorylation Cell fate specification in the lingual epithelium is controlled by antagonistic activities of Sonic hedgehog and retinoic acid Clinically severe CACNA1A alleles affect synaptic function and neurodegeneration differentially Control of RUNX-induced repression of Notch signaling by MLF and its partner DnaJ-1 during Drosophila hematopoiesis Detecting epistasis with the marginal epistasis test in genetic mapping studies of quantitative traits Dynactin binding to tyrosinated microtubules promotes centrosome centration in C. elegans by enhancing dynein-mediated organelle transport Dynamic hyper-editing underlies temperature adaptation in Drosophila EGFR controls Drosophila tracheal tube elongation by intracellular trafficking regulation Elimination of huntingtin in the adult mouse leads to progressive behavioral deficits,bilateral thalamic calcification,and altered brain iron homeostasis Evolution and multiple roles of the Pancrustacea specific transcription factor zelda in insects Filamin actin-binding and titin-binding fulfill distinct functions in Z-disc cohesion Genetic compensation: A phenomenon in search of mechanisms Genetic control of the root system in rice under normal and drought stress conditions by genome-wide association study Germline and reproductive tract effects intensify in male mice with successive generations of estrogenic exposure Hand factor ablation causes defective left ventricular chamber development and compromised adult cardiac function Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing Kinesin-1 promotes chondrocyte maintenance during skeletal morphogenesis Krox20 hindbrain regulation incorporates multiple modes of cooperation between cis-acting elements MiR-1254 suppresses HO-1 expression through seed region-dependent silencing and non-seed interaction with TFAP2A transcript to attenuate NSCLC growth Modular function of long noncoding RNA,COLDAIR,in the vernalization response Mouse models of 17q21.31 microdeletion and microduplication syndromes highlight the importance of Kansl1 for cognition Multiple renal cancer susceptibility polymorphisms modulate the HIF pathway Mutations in the Caenorhabditis elegans orthologs of human genes required for mitochondrial tRNA modification cause similar electron transport chain defects but different nuclear responses Natural variation in a single amino acid substitution underlies physiological responses to topoisomerase II poisons NlpD links cell wall remodeling and outer membrane invagination during cytokinesis in Escherichia coli Notch-dependent epithelial fold determines boundary formation between developmental fields in the Drosophila antenna Novel CRISPR/Cas9 gene drive constructs reveal insights into mechanisms of resistance allele formation and drive efficiency in genetically diverse populations Nuclear/cytoplasmic transport defects in BBS6 underlie congenital heart disease through perturbation of a chromatin remodeling protein OsCNGC13 promotes seed-setting rate by facilitating pollen tube growth in stylar tissues Persistent damaged bases in DNA allow mutagenic break repair in Escherichia coli Processing closely spaced lesions during Nucleotide Excision Repair triggers mutagenesis in E. coli Reduced dosage of the chromosome axis factor Red1 selectively disrupts the meiotic recombination checkpoint in Saccharomyces cerevisiae Replication stress affects the fidelity of nucleosome-mediated epigenetic inheritance Statistical correction of the Winner’s Curse explains replication variability in quantitative trait genome-wide association studies Stochasticity in the enterococcal sex pheromone response revealed by quantitative analysis of transcription in single cells Switching of dominant retrotransposon silencing strategies from posttranscriptional to transcriptional mechanisms during male germ-cell development in mice Systematic identification and characterization of regulatory elements derived from human endogenous retroviruses Systematic tissue-specific functional annotation of the human genome highlights immune-related DNA elements for late-onset Alzheimer’s disease T-DNA-Genome junctions form early after infection and are influenced by the chromatin state of the host genome Temporal dynamics of neurogenomic plasticity in response to social interactions in male threespined sticklebacks Termination factor Rho: From the control of pervasive transcription to cell fate determination in Bacillus subtilis Tex19.1 promotes Spo11-dependent meiotic recombination in mouse spermatocytes The Drosophila Duox maturation factor is a key component of a positive feedback loop that sustains regeneration signaling The RhoJ-BAD signaling network: An Achilles’ heel for BRAF mutant melanomas The T-cell leukemia related rpl10-R98S mutant traps the 60S export adapter Nmd3 in the ribosomal P site in yeast The ancestral levels of transcription and the evolution of sexual phenotypes in filamentous fungi The gene drive bubble: New realities The mecillinam resistome reveals a role for peptidoglycan endopeptidases in stimulating cell wall synthesis in Escherichia coli The miR-23a~27a~24-2 microRNA cluster buffers transcription and signaling pathways during hematopoiesis The nucleoid occlusion factor Noc controls DNA replication initiation in Staphylococcus aureus The nucleoid occlusion protein SlmA is a direct transcriptional activator of chitobiose utilization in Vibrio cholerae The population genomics of archaeological transition in west Iberia: Investigation of ancient substructure using imputation and haplotype-based methods Use of a microfluidic platform to uncover basic features of energy and environmental stress responses in individual cells of Bacillus subtilis Xist RNA repeat E is essential for ASH2L recruitment to the inactive X and regulates histone modifications and escape gene expression Yorkie is required to restrict the injury responses in planarians Zebrafish slc30a10 deficiency revealed a novel compensatory mechanism of Atp2c1 in maintaining manganese homeostasis