A Complex Genetic Switch Involving Overlapping Divergent Promoters and DNA Looping Regulates Expression of Conjugation Genes of a Gram-positive Plasmid

    A Conserved Role for p48 Homologs in Protecting Dopaminergic Neurons from Oxidative Stress

    A Gain-of-Function Mutation in Tnni2 Impeded Bone Development through Increasing Hif3a Expression in DA2B Mice

    A Mouse Model Uncovers LKB1 as an UVB-Induced DNA Damage Sensor Mediating CDKN1A (p21WAF1/CIP1) Degradation

    A Mutation in the Mouse Ttc26 Gene Leads to Impaired Hedgehog Signaling

    A Role for Taiman in Insect Metamorphosis

    A Splice Mutation in the PHKG1 Gene Causes High Glycogen Content and Low Meat Quality in Pig Skeletal Muscle

    Abnormal Dosage of Ultraconserved Elements Is Highly Disfavored in Healthy Cells but Not Cancer Cells

    An AGEF-1/Arf GTPase/AP-1 Ensemble Antagonizes LET-23 EGFR Basolateral Localization and Signaling during C. elegans Vulva Induction

    An ARHGEF10 Deletion Is Highly Associated with a Juvenile-Onset Inherited Polyneuropathy in Leonberger and Saint Bernard Dogs

    An Integrated Cell Purification and Genomics Strategy Reveals Multiple Regulators of Pancreas Development

    Analysis of Candida albicans Mutants Defective in the Cdk8 Module of Mediator Reveal Links between Metabolism and Biofilm Formation

    Ancient Expansion of the Hox Cluster in Lepidoptera Generated Four Homeobox Genes Implicated in Extra-Embryonic Tissue Formation

    At Short Telomeres Tel1 Directs Early Replication and Phosphorylates Rif1

    BMP-FGF Signaling Axis Mediates Wnt-Induced Epidermal Stratification in Developing Mammalian Skin

    Basement Membrane and Cell Integrity of Self-Tissues in Maintaining Drosophila Immunological Tolerance

    Beclin 1 Is Required for Neuron Viability and Regulates Endosome Pathways via the UVRAG-VPS34 Complex

    Break-Induced Replication Requires DNA Damage-Induced Phosphorylation of Pif1 and Leads to Telomere Lengthening

    COE Loss-of-Function Analysis Reveals a Genetic Program Underlying Maintenance and Regeneration of the Nervous System in Planarians

    Caudal Regulates the Spatiotemporal Dynamics of Pair-Rule Waves in Tribolium

    Cell-Autonomous Progeroid Changes in Conditional Mouse Models for Repair Endonuclease XPG Deficiency

    Coexistence and Within-Host Evolution of Diversified Lineages of Hypermutable Pseudomonas aeruginosa in Long-term Cystic Fibrosis Infections

    Comprehensive Mapping of the Escherichia coli Flagellar Regulatory Network

    Controlling Meiotic Recombinational Repair – Specifying the Roles of ZMMs,Sgs1 and Mus81/Mms4 in Crossover Formation

    Copy Number Variation in the Horse Genome

    De Novo Mutations in Moderate or Severe Intellectual Disability

    Developmentally-Regulated Excision of the SPβ Prophage Reconstitutes a Gene Required for Spore Envelope Maturation in Bacillus subtilis

    Disruption of SUMO-Specific Protease 2 Induces Mitochondria Mediated Neurodegeneration

    Dominant Sequences of Human Major Histocompatibility Complex Conserved Extended Haplotypes from HLA-DQA2 to DAXX

    Dynamic Partnership between TFIIH,PGC-1α and SIRT1 Is Impaired in Trichothiodystrophy

    Erratum: Comprehensive Mapping of the Escherichia coli Flagellar Regulatory Network (PLoS Genet,(2014),10,10 (e1004807))

    Erratum: Differential Responses to Wnt and PCP Disruption Predict Expression and Developmental Function of Conserved and Novel Genes in a Cnidarian (PLoS Genet,(2014),10,10 (e1004781))

    Erratum: Functional EF-Hands in Neuronal Calcium Sensor GCAP2 Determine Its Phosphorylation State and Subcellular Distribution In Vivo,and Are Essential for Photoreceptor Cell Integrity (PLoS Genet,(2014),10,10 (e1004744))

    Erratum: Genomic Restructuring in the Tasmanian Devil Facial Tumour: Chromosome Painting and Gene Mapping Provide Clues to Evolution of a Transmissible Tumour (PLoS Genet,(2014),10,10 (e1004840))

    Erratum: Global Genetic Variations Predict Brain Response to Faces (PLoS Genet,(2014),10,10 (e1004802))

    Erratum: Hecate/Grip2a Acts to Reorganize the Cytoskeleton in the Symmetry-Breaking Event of Embryonic Axis Induction (PLoS Genet,(2014),10,10 (e1004786))

    Erratum: Mechanisms of CFTR Functional Variants That Impair Regulated Bicarbonate Permeation and Increase Risk for Pancreatitis but Not for Cystic Fibrosis (PLoS Genet,(2014),10,10 (e1004778))

    Erratum: Memory and Fitness Optimization of Bacteria under Fluctuating Environments (PLoS Genet,(2014),10,10 (e1004793))

    Erratum: Requirements for Pseudomonas aeruginosa Acute Burn and Chronic Surgical Wound Infection (PLoS Genet,(2014),10,10 (e1004743))

    Ethylene-Induced Inhibition of Root Growth Requires Abscisic Acid Function in Rice (Oryza sativa L.) Seedlings

    Evidence of a Bacterial Receptor for Lysozyme: Binding of Lysozyme to the Anti-σ Factor RsiV Controls Activation of the ECF σ Factor σV

    Examination of Prokaryotic Multipartite Genome Evolution through Experimental Genome Reduction

    FHIT Suppresses Epithelial-Mesenchymal Transition (EMT) and Metastasis in Lung Cancer through Modulation of MicroRNAs

    Fast Evolution from Precast Bricks: Genomics of Young Freshwater Populations of Threespine Stickleback Gasterosteus aculeatus

    Fat-Dachsous Signaling Coordinates Cartilage Differentiation and Polarity during Craniofacial Development

    Feeding State,Insulin and NPR-1 Modulate Chemoreceptor Gene Expression via Integration of Sensory and Circuit Inputs

    Foxf Genes Integrate Tbx5 and Hedgehog Pathways in the Second Heart Field for Cardiac Septation

    Functional Interaction between Ribosomal Protein L6 and RbgA during Ribosome Assembly

    Genetic Influences on Translation in Yeast

    Genetic Modifiers of Neurofibromatosis Type 1-Associated Café-au-Lait Macule Count Identified Using Multi-platform Analysis

    Genome-Wide Association Study of CSF Levels of 59 Alzheimer's Disease Candidate Proteins: Significant Associations with Proteins Involved in Amyloid Processing and Inflammation

    Genome-Wide Discovery of Drug-Dependent Human Liver Regulatory Elements

    Genome-Wide Distribution of RNA-DNA Hybrids Identifies RNase H Targets in tRNA Genes,Retrotransposons and Mitochondria

    Genome-Wide Mapping of Yeast RNA Polymerase II Termination

    Germline Mutations in MAP3K6 Are Associated with Familial Gastric Cancer

    H2B Mono-ubiquitylation Facilitates Fork Stalling and Recovery during Replication Stress by Coordinating Rad53 Activation and Chromatin Assembly

    HIPPO Pathway Members Restrict SOX2 to the Inner Cell Mass Where It Promotes ICM Fates in the Mouse Blastocyst

    Hsp40s Specify Functions of Hsp104 and Hsp90 Protein Chaperone Machines

    Identification of Genes Important for Cutaneous Function Revealed by a Large Scale Reverse Genetic Screen in the Mouse

    Integrating Functional Data to Prioritize Causal Variants in Statistical Fine-Mapping Studies

    It's All in Your Mind: Determining Germ Cell Fate by Neuronal IRE-1 in C. elegans

    Juvenile Hormone-Receptor Complex Acts on Mcm4 and Mcm7 to Promote Polyploidy and Vitellogenesis in the Migratory Locust

    KDM5 Interacts with Foxo to Modulate Cellular Levels of Oxidative Stress

    Keeping mtDNA in Shape between Generations

    Keratin 76 Is Required for Tight Junction Function and Maintenance of the Skin Barrier

    Licensing of Yeast Centrosome Duplication Requires Phosphoregulation of Sfi1

    MMS Exposure Promotes Increased MtDNA Mutagenesis in the Presence of Replication-Defective Disease-Associated DNA Polymerase γ Variants

    Mechanism of Suppression of Chromosomal Instability by DNA Polymerase POLQ

    Metabolic Respiration Induces AMPK- and Ire1p-Dependent Activation of the p38-Type HOG MAPK Pathway

    Mmp1 Processing of the PDF Neuropeptide Regulates Circadian Structural Plasticity of Pacemaker Neurons

    Multifaceted Genome Control by Set1 Dependent and Independent of H3K4 Methylation and the Set1C/COMPASS Complex

    Multiple Regulatory Systems Coordinate DNA Replication with Cell Growth in Bacillus subtilis

    Nephronophthisis-Associated CEP164 Regulates Cell Cycle Progression,Apoptosis and Epithelial-to-Mesenchymal Transition

    Notch3 Interactome Analysis Identified WWP2 as a Negative Regulator of Notch3 Signaling in Ovarian Cancer

    Oligoasthenoteratozoospermia and Infertility in Mice Deficient for miR-34b/c and miR-449 Loci

    POT1a and Components of CST Engage Telomerase and Regulate Its Activity in Arabidopsis

    Payoffs,Not Tradeoffs,in the Adaptation of a Virus to Ostensibly Conflicting Selective Pressures

    Protein Phosphatase 4 Promotes Chromosome Pairing and Synapsis,and Contributes to Maintaining Crossover Competence with Increasing Age

    RNA-Processing Protein TDP-43 Regulates FOXO-Dependent Protein Quality Control in Stress Response

    Recovery from an Acute Infection in C. elegans Requires the GATA Transcription Factor ELT-2

    Ribosomal Readthrough at a Short UGA Stop Codon Context Triggers Dual Localization of Metabolic Enzymes in Fungi and Animals

    Role of STN1 and DNA Polymerase α in Telomere Stability and Genome-Wide Replication in Arabidopsis

    Role of abd-A and Abd-B in Development of Abdominal Epithelia Breaks Posterior Prevalence Rule

    Salt-Induced Stabilization of EIN3/EIL1 Confers Salinity Tolerance by Deterring ROS Accumulation in Arabidopsis

    Selection on a Variant Associated with Improved Viral Clearance Drives Local,Adaptive Pseudogenization of Interferon Lambda 4 (IFNL4)

    Sensors at Centrosomes Reveal Determinants of Local Separase Activity

    Signature Gene Expression Reveals Novel Clues to the Molecular Mechanisms of Dimorphic Transition in Penicillium marneffei

    Spinster Homolog 2 (Spns2) Deficiency Causes Early Onset Progressive Hearing Loss

    Systematic Dissection of Coding Exons at Single Nucleotide Resolution Supports an Additional Role in Cell-Specific Transcriptional Regulation

    TIF-IA-Dependent Regulation of Ribosome Synthesis in Drosophila Muscle Is Required to Maintain Systemic Insulin Signaling and Larval Growth

    Targeted Exon Capture and Sequencing in Sporadic Amyotrophic Lateral Sclerosis

    Telomeric ORFs (TLOs) in Candida spp. Encode Mediator Subunits That Regulate Distinct Virulence Traits

    The Analysis of Mutant Alleles of Different Strength Reveals Multiple Functions of Topoisomerase 2 in Regulation of Drosophila Chromosome Structure

    The Chromosomal Association of the Smc5/6 Complex Depends on Cohesion and Predicts the Level of Sister Chromatid Entanglement

    The DAF-16 FOXO Transcription Factor Regulates natc-1 to Modulate Stress Resistance in Caenorhabditis elegans,Linking Insulin/IGF-1 Signaling to Protein N-Terminal Acetylation

    The Formation of Endoderm-Derived Taste Sensory Organs Requires a Pax9-Dependent Expansion of Embryonic Taste Bud Progenitor Cells

    The Kinesin AtPSS1 Promotes Synapsis and is Required for Proper Crossover Distribution in Meiosis

    The Listeria Small RNA Rli27 Regulates a Cell Wall Protein inside Eukaryotic Cells by Targeting a Long 5′-UTR Variant

    The Master Activator of IncA/C Conjugative Plasmids Stimulates Genomic Islands and Multidrug Resistance Dissemination

    The Not5 Subunit of the Ccr4-Not Complex Connects Transcription and Translation

    The Nuclear Immune Receptor RPS4 Is Required for RRS1SLH1-Dependent Constitutive Defense Activation in Arabidopsis thaliana

    The Proteomic Landscape of the Suprachiasmatic Nucleus Clock Reveals Large-Scale Coordination of Key Biological Processes

    The Specification and Global Reprogramming of Histone Epigenetic Marks during Gamete Formation and Early Embryo Development in C. elegans

    The Vesicle Protein SAM-4 Regulates the Processivity of Synaptic Vesicle Transport

    The bHLH-PAS Transcription Factor Dysfusion Regulates Tarsal Joint Formation in Response to Notch Activity during Drosophila Leg Development

    Topoisomerase II Is Required for the Proper Separation of Heterochromatic Regions during Drosophila melanogaster Female Meiosis

    Tpz1-Ccq1 and Tpz1-Poz1 Interactions within Fission Yeast Shelterin Modulate Ccq1 Thr93 Phosphorylation and Telomerase Recruitment

    Uncovering Enhancer Functions Using the α-Globin Locus

    Unifying Genetic Canalization,Genetic Constraint,and Genotype-by-Environment Interaction: QTL by Genomic Background by Environment Interaction of Flowering Time in Boechera stricta

    White Cells Facilitate Opposite- and Same-Sex Mating of Opaque Cells in Candida albicans

    ZTF-8 Interacts with the 9-1-1 Complex and Is Required for DNA Damage Response and Double-Strand Break Repair in the C. elegans Germline

    daf-31 Encodes the Catalytic Subunit of N Alpha-Acetyltransferase that Regulates Caenorhabditis elegans Development,Metabolism and Adult Lifespan

    ssb Gene Duplication Restores the Viability of ΔholC and ΔholD Escherichia coli Mutants