A Missense Change in the ATG4D Gene Links Aberrant Autophagy to a Neurodegenerative Vacuolar Storage Disease

    A Multi-layered Protein Network Stabilizes the Escherichia coli FtsZ-ring and Modulates Constriction Dynamics

    A Non-canonical RNA Silencing Pathway Promotes mRNA Degradation in Basal Fungi

    A Single Nucleotide Polymorphism Uncovers a Novel Function for the Transcription Factor Ace2 during Candida albicans Hyphal Development

    A Stress-Induced Small RNA Modulates Alpha-Rhizobial Cell Cycle Progression

    Adventures in Wonderland

    Asymmetric Transcript Discovery by RNA-seq in C. elegans Blastomeres Identifies neg-1,a Gene Important for Anterior Morphogenesis

    Ataxin-2 Regulates RGS8 Translation in a New BAC-SCA2 Transgenic Mouse Model

    Auxin Influx Carriers Control Vascular Patterning and Xylem Differentiation in Arabidopsis thaliana

    Beyond Glycolysis: GAPDHs Are Multi-functional Enzymes Involved in Regulation of ROS,Autophagy,and Plant Immune Responses

    CAPER Is Vital for Energy and Redox Homeostasis by Integrating Glucose-Induced Mitochondrial Functions via ERR-α-Gabpa and Stress-Induced Adaptive Responses via NF-κB-cMYC

    Chromosome Replacement and Deletion Lead to Clonal Polymorphism of Berry Color in Grapevine

    Co-chaperone p23 Regulates C. elegans Lifespan in Response to Temperature

    Competition between VanUG Repressor and VanRG Activator Leads to Rheostatic Control of vanG Vancomycin Resistance Operon Expression

    Comprehensive Profiling of Amino Acid Response Uncovers Unique Methionine-Deprived Response Dependent on Intact Creatine Biosynthesis

    Contribution of Large Region Joint Associations to Complex Traits Genetics

    Correction To: Recurrent Evolution of Melanism in South American Felids (PLos Genet,11,4)

    Correction to: An AP Endonuclease Functions in Active DNA Demethylation and Gene Imprinting in Arabidopsis (PLoS Genet,11,4,(2015))

    Correction to: An Operon of Three Transcriptional Regulators Controls Horizontal Gene Transfer of the Integrative and Conjugative Element ICEclc in Pseudomonas knackmussii B13(PLoS Genet,(2015),11,4)

    Correction to: JNK Controls the Onset of Mitosis in Planarian Stem Cells and Triggers Apoptotic Cell Death Required for Regeneration and Remodeling(PLoS Genet,(2014),10,6,10.1371/journal.pgen.1004400)

    Correction to: Nicotiana Small RNA Sequences Support a Host Genome Origin of Cucumber Mosaic Virus Satellite RNA (PLoS Genet,11,4,(2015))

    Correction to: Recovery from an Acute Infection in C. elegans Requires the GATA Transcription Factor ELT-2 (PLoS Genet,(2015) 11,[4])

    Correction: Drosophila TIM Binds Importin α1,and Acts as an Adapter to Transport PER to the Nucleus (PLoS Genet,11(4),(2015))

    Correction: Essential Role for Endogenous siRNAs during Meiosis in Mouse Oocytes(PLoS Genet,(2015),11(2),Doi:10.1371/journal.pgen.1005013)

    Correction: Partially Redundant Enhancers Cooperatively Maintain Mammalian Pomc Expression Above a Critical Functional Threshold [PLoS Genet,11(4),(2015)]

    Correction: Pooled Sequencing of 531 Genes in Inflammatory Bowel Disease Identifies an Associated Rare Variant in BTNL2 and Implicates Other Immune Related Genes (PLoS Pathog,11,4)

    Correction: Quantitative Genetics of CTCF Binding Reveal Local Sequence Effects and Different Modes of X-Chromosome Association (PLoS Genet,11,4,(2015))

    Correction: acal Is a Long Non-coding RNA in JNK Signaling in Epithelial Shape Changes during Drosophila Dorsal Closure [PLoS Genet,11(4),(2015)]

    Cross-Population Joint Analysis of eQTLs: Fine Mapping and Functional Annotation

    DNA Damage Response and Spindle Assembly Checkpoint Function throughout the Cell Cycle to Ensure Genomic Integrity

    Distinct and Cooperative Activities of HESO1 and URT1 Nucleotidyl Transferases in MicroRNA Turnover in Arabidopsis

    Erratum to: Discovery of CTCF-Sensitive Cis-Spliced Fusion RNAs between Adjacent Genes in Human Prostate Cells (PLoS Genet,11,4)

    Erratum to: The EJC Binding and Dissociating Activity of PYM Is Regulated in Drosophila (PLoS Genet,11,4)

    Experimental Swap of Anopheles gambiae's Assortative Mating Preferences Demonstrates Key Role of X-Chromosome Divergence Island in Incipient Sympatric Speciation

    Extreme Recombination Frequencies Shape Genome Variation and Evolution in the Honeybee,Apis mellifera

    Genome Sequencing of the Perciform Fish Larimichthys crocea Provides Insights into Molecular and Genetic Mechanisms of Stress Adaptation

    Genome-Destabilizing Effects Associated with Top1 Loss or Accumulation of Top1 Cleavage Complexes in Yeast

    Genome-Wide Association Study Identifies Nox3 as a Critical Gene for Susceptibility to Noise-Induced Hearing Loss

    Genome-Wide Negative Feedback Drives Transgenerational DNA Methylation Dynamics in Arabidopsis

    Genomic Location of the Major Ribosomal Protein Gene Locus Determines Vibrio cholerae Global Growth and Infectivity

    Heterozygosity for a Hypomorphic Polβ Mutation Reduces the Expansion Frequency in a Mouse Model of the Fragile X-Related Disorders

    Host Genetic Variation Influences Gene Expression Response to Rhinovirus Infection

    Imputation-Based Population Genetics Analysis of Plasmodium falciparum Malaria Parasites

    Inhibiting K63 Polyubiquitination Abolishes No-Go Type Stalled Translation Surveillance in Saccharomyces cerevisiae

    Lack of GDAP1 Induces Neuronal Calcium and Mitochondrial Defects in a Knockout Mouse Model of Charcot-Marie-Tooth Neuropathy

    Lipid-Induced Epigenomic Changes in Human Macrophages Identify a Coronary Artery Disease-Associated Variant that Regulates PPAP2B Expression through Altered C/EBP-Beta Binding

    MAPK Signaling Pathway Alters Expression of Midgut ALP and ABCC Genes and Causes Resistance to Bacillus thuringiensis Cry1Ac Toxin in Diamondback Moth

    Maintenance of Glia in the Optic Lamina Is Mediated by EGFR Signaling by Photoreceptors in Adult Drosophila

    Multi-locus Analysis of Genomic Time Series Data from Experimental Evolution

    Ndd1 Turnover by SCFGrr1 Is Inhibited by the DNA Damage Checkpoint in Saccharomyces cerevisiae

    Neto-Mediated Intracellular Interactions Shape Postsynaptic Composition at the Drosophila Neuromuscular Junction

    Nxf1 Natural Variant E610G Is a Semi-dominant Suppressor of IAP-Induced RNA Processing Defects

    Postnatal Loss of Hap1 Reduces Hippocampal Neurogenesis and Causes Adult Depressive-Like Behavior in Mice

    Proteolysis of Virulence Regulator ToxR Is Associated with Entry of Vibrio cholerae into a Dormant State

    Re-replication of a Centromere Induces Chromosomal Instability and Aneuploidy

    Retraction: Astakine 2--the dark knight linking melatonin to circadian regulation in crustaceans - صفحه:e1005222-

    Retraction: Astakine 2—the Dark Knight Linking Melatonin to Circadian Regulation in Crustaceans [PLoS Genet,(2015)]

    SERPINB11 Frameshift Variant Associated with Novel Hoof Specific Phenotype in Connemara Ponies

    SYD-1C,UNC-40 (DCC) and SAX-3 (Robo) Function Interdependently to Promote Axon Guidance by Regulating the MIG-2 GTPase

    Selection against Heteroplasmy Explains the Evolution of Uniparental Inheritance of Mitochondria

    Shade Avoidance Components and Pathways in Adult Plants Revealed by Phenotypic Profiling

    Simultaneous Discovery,Estimation and Prediction Analysis of Complex Traits Using a Bayesian Mixture Model

    Spastin Binds to Lipid Droplets and Affects Lipid Metabolism

    Spatial Fluctuations in Expression of the Heterocyst Differentiation Regulatory Gene hetR in Anabaena Filaments

    Spatio-temporal Remodeling of Functional Membrane Microdomains Organizes the Signaling Networks of a Bacterium

    Synergistic and Independent Actions of Multiple Terminal Nucleotidyl Transferases in the 3’ Tailing of Small RNAs in Arabidopsis

    Systematic Dissection of the Sequence Determinants of Gene 3’ End Mediated Expression Control

    Systematic Profiling of Poly(A)+ Transcripts Modulated by Core 3’ End Processing and Splicing Factors Reveals Regulatory Rules of Alternative Cleavage and Polyadenylation

    The Chromatin Remodeler CHD8 Is Required for Activation of Progesterone Receptor-Dependent Enhancers

    The Cryptococcus neoformans Alkaline Response Pathway: Identification of a Novel Rim Pathway Activator

    The DNA Helicase Recql4 Is Required for Normal Osteoblast Expansion and Osteosarcoma Formation

    The Evolutionary Origination and Diversification of a Dimorphic Gene Regulatory Network through Parallel Innovations in cis and trans

    The Functional Interplay Between the t(9;22)-Associated Fusion Proteins BCR/ABL and ABL/BCR in Philadelphia Chromosome-Positive Acute Lymphatic Leukemia

    The Genetic Legacy of the Expansion of Turkic-Speaking Nomads across Eurasia

    The Lowe Syndrome Protein OCRL1 Is Required for Endocytosis in the Zebrafish Pronephric Tubule

    The Pif1 Helicase,a Negative Regulator of Telomerase,Acts Preferentially at Long Telomeres

    The Power of Gene-Based Rare Variant Methods to Detect Disease-Associated Variation and Test Hypotheses About Complex Disease

    The Protein Quality Control Machinery Regulates Its Misassembled Proteasome Subunits

    The UPR Branch IRE1-bZIP60 in Plants Plays an Essential Role in Viral Infection and Is Complementary to the Only UPR Pathway in Yeast

    Transgenerational Inheritance of Diet-Induced Genome Rearrangements in Drosophila

    Viable Neuronopathic Gaucher Disease Model in Medaka (Oryzias latipes) Displays Axonal Accumulation of Alpha-Synuclein

    Volatility of Mutator Phenotypes at Single Cell Resolution

    Windpipe Controls Drosophila Intestinal Homeostasis by Regulating JAK/STAT Pathway via Promoting Receptor Endocytosis and Lysosomal Degradation

    corraction To: Imputation of the Rare HOXB13 G84E Mutation and Cancer Risk in a Large Population-Based Cohort (PLoS Genet,11,4)