A Point Mutation in Suppressor of Cytokine Signalling 2 (Socs2) Increases the Susceptibility to Inflammation of the Mammary Gland while Associated with Higher Body Weight and Size and Higher Milk Production in a Sheep Model

    A Simple Model-Based Approach to Inferring and Visualizing Cancer Mutation Signatures

    An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies

    An Endosperm-Associated Cuticle Is Required for Arabidopsis Seed Viability,Dormancy and Early Control of Germination

    Arabidopsis COP1 SUPPRESSOR 2 Represses COP1 E3 Ubiquitin Ligase Activity through Their Coiled-Coil Domains Association

    Auxin Response Factor SlARF2 Is an Essential Component of the Regulatory Mechanism Controlling Fruit Ripening in Tomato

    Bacterial Proliferation: Keep Dividing and Don't Mind the Gap

    Brachyury,Foxa2 and the cis-Regulatory Origins of the Notochord

    Branched-Chain Aminotransferases Control TORC1 Signaling in Saccharomyces cerevisiae

    Catching a (Double-Strand) Break: The Rad51 and Dmc1 Strand Exchange Proteins Can Co-occupy Both Ends of a Meiotic DNA Double-Strand Break

    Co-evolution of Bacterial Ribosomal Protein S15 with Diverse mRNA Regulatory Structures

    Combined Genetic and Genealogic Studies Uncover a Large BAP1 Cancer Syndrome Kindred Tracing Back Nine Generations to a Common Ancestor from the 1700s

    Comparative Genomic Analyses of the Human NPHP1 Locus Reveal Complex Genomic Architecture and Its Regional Evolution in Primates

    Compound Heterozygosity for Y Box Proteins Causes Sterility Due to Loss of Translational Repression

    Comprehensive Identification of Long Non-coding RNAs in Purified Cell Types from the Brain Reveals Functional LncRNA in OPC Fate Determination

    Convergent Evolution of Hemoglobin Function in High-Altitude Andean Waterfowl Involves Limited Parallelism at the Molecular Sequence Level

    Correction To: Genome-Wide Analysis in German Shepherd Dogs Reveals Association of a Locus on CFA 27 with Atopic Dermatitis (PLoS Genet,11,12)

    Correction to: A Cytosine Methytransferase Modulates the Cell Envelope Stress Response in the Cholera Pathogen (PLoS Genet,(2015) 11,[11])

    Correction to: HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse (PLoS Genet,11,10,e1005620,10.1371/journal.pgen.1005620)

    Correction to: Notch Signaling Mediates the Age-Associated Decrease in Adhesion of Germline Stem Cells to the Niche(PLoS Genet,(2015),11,12)

    Correction: Histone H2AFX Links Meiotic Chromosome Asynapsis to Prophase I Oocyte Loss in Mammals(PLoS Genet,(2015),11(12))

    Correction: MoSET1 (Histone H3K4 Methyltransferase in Magnaporthe oryzae) Regulates Global Gene Expression during Infection-Related Morphogenesis(PLoS Genet,(2015),11(12))

    Correction: The Genomes of the Fungal Plant Pathogens Cladosporium fulvum and Dothistroma septosporum Reveal Adaptation to Different Hosts and Lifestyles But Also Signatures of Common Ancestry [PLoS Genet,11(12),(2015)]

    DLK-1/p38 MAP Kinase Signaling Controls Cilium Length by Regulating RAB-5 Mediated Endocytosis in Caenorhabditis elegans

    DNA Methylation: Insights into Human Evolution

    Developmental Dynamics of X-Chromosome Dosage Compensation by the DCC and H4K20me1 in C. elegans

    Dissecting the Genetic Basis of a Complex cis-Regulatory Adaptation

    Dynamic Roles for Small RNAs and DNA Methylation during Ovule and Fiber Development in Allotetraploid Cotton

    EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair

    EGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated Genes

    Escape from Lethal Bacterial Competition through Coupled Activation of Antibiotic Resistance and a Mobilized Subpopulation

    Estimating Information Processing in a Memory System: The Utility of Meta-analytic Methods for Genetics

    Fmrp Interacts with Adar and Regulates RNA Editing,Synaptic Density and Locomotor Activity in Zebrafish

    GDNF Overexpression from the Native Locus Reveals its Role in the Nigrostriatal Dopaminergic System Function

    Gene Regulatory Mechanisms Underlying the Spatial and Temporal Regulation of Target-Dependent Gene Expression in Drosophila Neurons

    Genetic Architecture of Atherosclerosis in Mice: A Systems Genetics Analysis of Common Inbred Strains

    Genome-Wide Scan Informed by Age-Related Disease Identifies Loci for Exceptional Human Longevity

    Genome-Wide Transcriptional Regulation Mediated by Biochemically Distinct SWI/SNF Complexes

    Genomic Insights into the Ancestry and Demographic History of South America

    Histamine Recycling Is Mediated by CarT,a Carcinine Transporter in Drosophila Photoreceptors

    Hnrnph1 Is A Quantitative Trait Gene for Methamphetamine Sensitivity

    Human β-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid

    Integration Analysis of Three Omics Data Using Penalized Regression Methods: An Application to Bladder Cancer

    Kicking against the PRCs – A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2

    LncRNA-HIT Functions as an Epigenetic Regulator of Chondrogenesis through Its Recruitment of p100/CBP Complexes

    Loss of the Yeast SR Protein Npl3 Alters Gene Expression Due to Transcription Readthrough

    Methionine Mistranslation Bypasses the Restraint of the Genetic Code to Generate Mutant Proteins with Distinct Activities

    Minor Loops in Major Folds: Enhancer–Promoter Looping,Chromatin Restructuring,and Their Association with Transcriptional Regulation and Disease

    Mouse Y-Encoded Transcription Factor Zfy2 Is Essential for Sperm Formation and Function in Assisted Fertilization

    Multifactorial Competition and Resistance in a Two-Species Bacterial System

    New Perspectives on DNA and RNA Triplexes As Effectors of Biological Activity

    Origin-Dependent Inverted-Repeat Amplification: Tests of a Model for Inverted DNA Amplification

    Origins of De Novo Genes in Human and Chimpanzee

    PLOS Genetics Data Sharing Policy: In Pursuit of Functional Utility

    Probing Xist RNA Structure in Cells Using Targeted Structure-Seq

    RAB-10 Regulates Dendritic Branching by Balancing Dendritic Transport

    RNA Polymerase III Output Is Functionally Linked to tRNA Dimethyl-G26 Modification

    Recruitment of Mediator Complex by Cell Type and Stage-Specific Factors Required for Tissue-Specific TAF Dependent Gene Activation in an Adult Stem Cell Lineage

    Reproductive Aging Drives Protein Accumulation in the Uterus and Limits Lifespan in C. elegans

    Retromer Is Essential for Autophagy-Dependent Plant Infection by the Rice Blast Fungus

    Seed Dormancy in Arabidopsis Requires Self-Binding Ability of DOG1 Protein and the Presence of Multiple Isoforms Generated by Alternative Splicing

    Sex Pheromones of C. elegans Males Prime the Female Reproductive System and Ameliorate the Effects of Heat Stress

    Skp1 Independent Function of Cdc53/Cul1 in F-box Protein Homeostasis

    Small Rad51 and Dmc1 Complexes Often Co-occupy Both Ends of a Meiotic DNA Double Strand Break

    Stable Pseudohyphal Growth in Budding Yeast Induced by Synergism between Septin Defects and Altered MAP-kinase Signaling

    The Drosophila Zinc Finger Transcription Factor Ouija Board Controls Ecdysteroid Biosynthesis through Specific Regulation of spookier

    The Epitranscriptome and Innate Immunity

    The Eukaryotic Mismatch Recognition Complexes Track with the Replisome during DNA Synthesis

    The Inflammatory Transcription Factors NFκB,STAT1 and STAT3 Drive Age-Associated Transcriptional Changes in the Human Kidney

    The Mammalian Orthologs of Drosophila Lgd,CC2D1A and CC2D1B,Function in the Endocytic Pathway,but Their Individual Loss of Function Does Not Affect Notch Signalling

    The Nuclear Matrix Protein Megator Regulates Stem Cell Asymmetric Division through the Mitotic Checkpoint Complex in Drosophila Testes

    The Ribosome Biogenesis Protein Nol9 Is Essential for Definitive Hematopoiesis and Pancreas Morphogenesis in Zebrafish

    The Sex Determination Gene transformer Regulates Male-Female Differences in Drosophila Body Size

    Top2 and Sgs1-Top3 Act Redundantly to Ensure rDNA Replication Termination

    Transcript Expression Data from Human Islets Links Regulatory Signals from Genome-Wide Association Studies for Type 2 Diabetes and Glycemic Traits to Their Downstream Effectors

    Trehalose Accumulation Triggers Autophagy during Plant Desiccation

    Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome

    Trm9-Catalyzed tRNA Modifications Regulate Global Protein Expression by Codon-Biased Translation

    Tyro3 Modulates Mertk-Associated Retinal Degeneration

    Understanding Biases in Ribosome Profiling Experiments Reveals Signatures of Translation Dynamics in Yeast

    Viral Transmission Dynamics at Single-Cell Resolution Reveal Transiently Immune Subpopulations Caused by a Carrier State Association

    Why Are tRNAs Overproduced in the Absence of Maf1,a Negative Regulator of RNAP III,Not Fully Functional?

    Women Who Don't Give a Crap

    dbl-1/TGF-β and daf-12/NHR Signaling Mediate Cell-Nonautonomous Effects of daf-16/FOXO on Starvation-Induced Developmental Arrest

    fMiRNA-192 and miRNA-204 Directly Suppress lncRNA HOTTIP and Interrupt GLS1-Mediated Glutaminolysis in Hepatocellular Carcinoma