plos genetics سال:2012 - دوره:8

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plos genetics
سال:2012 - دوره:8 - شماره:3

A downstream CpG island controls transcript initiation and elongation and the methylation state of the imprinted airn macro ncRNA promoter A fundamental regulatory mechanism operating through OmpR and DNA topology controls expression of salmonella pathogenicity islands SPI-1 and SPI-2 A genome-wide association study identifies variants underlying the arabidopsis thaliana shade avoidance response A genome-wide association study of nephrolithiasis in the Japanese population identifies novel susceptible loci at 5q35.3,7p14.3,and 13q14.1 A genome-wide scan of ashkenazi jewish crohn's disease suggests novel susceptibility loci A machine learning approach for identifying novel cell type-specific transcriptional regulators of myogenesis A meta-analysis and genome-wide association study of platelet count and mean platelet volume in African Americans A natural system of chromosome transfer in yersinia pseudotuberculosis A quantitative,high-throughput reverse genetic screen reveals novel connections between pre-mRNA splicing and 5′ and 3′ end transcript determinants A splice site variant in the bovine rnf11 gene compromises growth and regulation of the inflammatory response A systematic analysis of cell cycle regulators in yeast reveals that most factors act independently of cell size to control initiation of division APOBEC3G-induced hypermutation of human immunodeficiency virus type-1 is typically a discrete all or nothing phenomenon Accurate prediction of inducible transcription factor binding intensities in Vivo Age-dependent brain gene expression and copy number anomalies in autism suggest distinct pathological processes at young versus mature ages Akirin links twist-regulated transcription with the brahma chromatin remodeling complex during embryogenesis An alu element-associated hypermethylation variant of the POMC gene is associated with childhood obesity Antagonistic regulation of apoptosis and differentiation by the cut transcription factor represents a tumor-suppressing mechanism in drosophila Autoregulation of the drosophila noncoding roX1 RNA gene Balanced codon usage optimizes eukaryotic translational efficiency Broad-specificity mrna-rrna complementarity in efficient protein translation Cell size and the initiation of DNA replication in bacteria Cis-by-trans regulatory divergence causes the asymmetric lethal effects of an ancestral hybrid incompatibility gene Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDgene database Contrasted patterns of molecular evolution in dominant and recessive self-incompatibility haplotypes in Arabidopsis Critical evaluation of imprinted gene expression by RNA-seq: A new perspective DNA damage in nijmegen breakage syndrome cells leads to PARP hyperactivation and increased oxidative stress DNA resection at chromosome breaks promotes genome stability by constraining non-allelic homologous recombination Development of a panel of genome-wide ancestry informative markers to study admixture throughout the americas Diverse forms of RPS9 splicing are part of an evolving autoregulatory circuit EMF1 and PRC2 cooperate to repress key regulators of arabidopsis development Error-prone ZW pairing and no evidence for meiotic sex chromosome inactivation in the chicken germ line Evidence for positive selection on a number of microRNA regulatory interactions during recent human evolution Exploring the complexity of the HIV-1 fitness landscape Gene reactivation by 5-aza-2′-deoxycytidine-induced demethylation requires srcap-mediated H2A.Z insertion to establish nucleosome depleted regions Genetic analysis of floral symmetry in van gogh's sunflowers reveals independent recruitment of CYCLOIDEA genes in the asteraceae Genetic architecture of highly complex chemical resistance traits across four yeast strains Genetic basis of hidden phenotypic variation revealed by increased translational readthrough in yeast Genome-wide association and functional follow-up reveals new loci for kidney function Genomic analysis of the hydrocarbon-producing,cellulolytic,endophytic fungus ascocoryne sarcoides Genomic tools for evolution and conservation in the chimpanzee: Pan troglodytes ellioti is a genetically distinct population Heritability and genetic correlations explained by common SNPS for metabolic syndrome traits Igf1r signaling is indispensable for preimplantation development and is activated via a novel function of E-cadherin Imprinted genes... and the number is? Insulin/IGF-1 and hypoxia signaling act in concert to regulate iron homeostasis in Caenorhabditis elegans Interpreting meta-analyses of genome-wide association studies Intracranial aneurysm risk locus 5q23.2 is associated with elevated systolic blood pressure Intronic cis-regulatory modules mediate tissue-specific and microbial control of angptl4/fiaf transcription LMW-E/CDK2 deregulates acinar morphogenesis,induces tumorigenesis,and associates with the activated b-raf-ERK1/2-mTOR pathway in breast cancer patients Lin-28 controls the succession of cell fate choices via two distinct activities MNS1 is essential for spermiogenesis and motile ciliary functions in mice Mammalian neurogenesis requires treacle-Plk1 for precise control of spindle orientation,mitotic progression,and maintenance of neural progenitor cells Mapping the Hsp90 genetic interaction network in candida albicans reveals environmental contingency and rewired circuitry Metabolic profiling of a mapping population exposes new insights in the regulation of seed metabolism and seed,fruit,and plant relations Mitochondrial oxidative stress alters a pathway in caenorhabditis elegans strongly resembling that of bile acid biosynthesis and secretion in vertebrates Modelling human regulatory variation in mouse: Finding the function in genome-wide association studies and whole-genome sequencing Mouse genetics suggests cell-context dependency for myc-regulated metabolic enzymes during tumorigenesis Networks of neuronal genes affected by common and rare variants in autism spectrum disorders Neurobeachin,a regulator of synaptic protein targeting,is associated with body fat mass and feeding behavior in mice and body-mass index in humans Nos2 inactivation promotes the development of medulloblastoma in ptch1 +/- mice by deregulation of Gap43-dependent granule cell precursor migration Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: A multi-ethnic meta-analysis of 45,891 individuals Parkinson's disease-associated kinase PINK1 regulates miro protein level and axonal transport of mitochondria Phenotypic plasticity of the drosophila transcriptome Phosphorylation of the drosophila melanogaster rna-binding protein how by MAPK/ERK enhances its dimerization and activity Physiological notch signaling maintains bone homeostasis via RBPjk and hey upstream of NFATc1 Pif4-mediated activation of yucca8 expression integrates temperature into the auxin pathway in regulating arabidopsis hypocotyl growth Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal Ppk23-dependent chemosensory functions contribute to courtship behavior in drosophila melanogaster Precocious metamorphosis in the juvenile hormone-deficient mutant of the silkworm,Bombyx mori Probing the informational and regulatory plasticity of a transcription factor DNA-binding domain Promoter nucleosome organization shapes the evolution of gene expression REST-mediated recruitment of polycomb repressor complexes in mammalian cells Rapid analysis of saccharomyces cerevisiae genome rearrangements by multiplex ligation-dependent probe amplification Repression of germline RNAi pathways in somatic cells by retinoblastoma pathway chromatin complexes SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians Spo0A~p imposes a temporal gate for the bimodal expression of competence in bacillus subtilis Statistical analysis of readthrough levels for nonsense mutations in mammalian cells reveals a major determinant of response to gentamicin Synthetic lethality of cohesins with PARPs and replication fork mediators Tcf7 is an important regulator of the switch of self-renewal and differentiation in a multipotential hematopoietic cell line Temporal transcriptional profiling of somatic and germ cells reveals biased lineage priming of sexual fate in the fetal mouse gonad The Ciliogenic Transcription Factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development The atypical calpains: Evolutionary analyses and roles in Caenorhabditis elegans cellular degeneration The human pancreatic islet transcriptome: Expression of candidate genes for type 1 diabetes and the impact of pro-inflammatory cytokines The miR-35-41 family of microRNAs regulates RNAi sensitivity in caenorhabditis elegans The min system and nucleoid occlusion are not required for identifying the division site in bacillus subtilis but ensure its efficient utilization The nucleoside diphosphate kinase gene nme3 acts as quantitative trait locus promoting non-mendelian inheritance The silkworm coming of age-early The transcription factor ultraspiracle influences honey bee social behavior and behavior-related gene expression The yeast forkhead transcription factors fkh1 and fkh2 regulate lifespan and stress response together with the anaphase-promoting complex Three essential ribonucleases-RNase Y,J1,and III-control the abundance of a majority of bacillus subtilis mRNAs Too much cleavage of cyclin E promotes breast tumorigenesis Transcriptional control in cardiac progenitors: Tbx1 interacts with the BAF chromatin remodeling complex and regulates Wnt5a Variation in msra modifies risk of neonatal intestinal obstruction in cystic fibrosis Widespread site-dependent buffering of human regulatory polymorphism