plos genetics سال:2013 - دوره:9

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plos genetics
سال:2013 - دوره:9 - شماره:4

A Big Catch for Germ Cell Tumour Research A Nonsynonymous Polymorphism in Semaphorin 3A as a Risk Factor for Human Unexplained Cardiac Arrest with Documented Ventricular Fibrillation ATP-Dependent Chromatin Remodeling by Cockayne Syndrome Protein B and NAP1-Like Histone Chaperones Is Required for Efficient Transcription-Coupled DNA Repair Aag DNA Glycosylase Promotes Alkylation-Induced Tissue Damage Mediated by Parp1 Aconitase Causes Iron Toxicity in Drosophila pink1 Mutants All SNPs are not created equal: Genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs An Essential Role for Zygotic Expression in the Pre-Cellular Drosophila Embryo Analysis of Rare,Exonic Variation amongst Subjects with Autism Spectrum Disorders and Population Controls Asynchronous Replication,Mono-Allelic Expression,and Long Range Cis-Effects of ASAR6 Balancing Selection on a Regulatory Region Exhibiting Ancient Variation That Predates Human-Neandertal Divergence Bisphenol A Exposure Disrupts Genomic Imprinting in the Mouse Breakpoint Analysis of Transcriptional and Genomic Profiles Uncovers Novel Gene Fusions Spanning Multiple Human Cancer Types Comparative Genomics of Wolbachia and the Bacterial Species Concept Comprehensive Assignment of Roles for Salmonella Typhimurium Genes in Intestinal Colonization of Food-Producing Animals Continent-Wide Decoupling of Y-Chromosomal Genetic Variation from Language and Geography in Native South Americans Coordinated Cell Type-Specific Epigenetic Remodeling in Prefrontal Cortex Begins before Birth and Continues into Early Adulthood Cytotoxic Chromosomal Targeting by CRISPR/Cas Systems Can Reshape Bacterial Genomes and Expel or Remodel Pathogenicity Islands DNA Double-Strand Breaks Coupled with PARP1 and HNRNPA2B1 Binding Sites Flank Coordinately Expressed Domains in Human Chromosomes Dialects of the DNA Uptake Sequence in Neisseriaceae Differential Association of the Conserved SUMO Ligase Zip3 with Meiotic Double-Strand Break Sites Reveals Regional Variations in the Outcome of Meiotic Recombination Disruption of TTDA Results in Complete Nucleotide Excision Repair Deficiency and Embryonic Lethality Drosophila DJ-1 Decreases Neural Sensitivity to Stress by Negatively Regulating Daxx-Like Protein through dFOXO Drosophila cyfip Regulates Synaptic Development and Endocytosis by Suppressing Filamentous Actin Assembly Epigenetic Upregulation of lncRNAs at 13q14.3 in Leukemia Is Linked to the In Cis Downregulation of a Gene Cluster That Targets NF-kB Evolution after Introduction of a Novel Metabolic Pathway Consistently Leads to Restoration of Wild-Type Physiology Extensive Natural Epigenetic Variation at a De Novo Originated Gene Focusing In on the Complex Genetics of Myopia Functional Dissection of the Drosophila melanogaster Condensin Subunit Cap-G Reveals Its Exclusive Association with Condensin I Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases Genetic Requirements for Signaling from an Autoactive Plant NB-LRR Intracellular Innate Immune Receptor Genetic and Biochemical Assays Reveal a Key Role for Replication Restart Proteins in Group II Intron Retrohoming Genetic and Genomic Architecture of the Evolution of Resistance to Antifungal Drug Combinations Genome-Wide Association Studies Identify Two Novel BMP15 Mutations Responsible for an Atypical Hyperprolificacy Phenotype in Sheep High-Resolution Mapping of Spontaneous Mitotic Recombination Hotspots on the 1.1 Mb Arm of Yeast Chromosome IV High-resolution mapping of h1 linker histone variants in embryonic stem cells - صفحه:e1003417- Identification of Rtl1,a Retrotransposon-Derived Imprinted Gene,as a Novel Driver of Hepatocarcinogenesis Identification of a Tissue-Selective Heat Shock Response Regulatory Network Improved Detection of Common Variants Associated with Schizophrenia and Bipolar Disorder Using Pleiotropy-Informed Conditional False Discovery Rate Insulators Target Active Genes to Transcription Factories and Polycomb-Repressed Genes to Polycomb Bodies Intrinsic Epigenetic Regulation of the D4Z4 Macrosatellite Repeat in a Transgenic Mouse Model for FSHD Iron-Responsive miR-485-3p Regulates Cellular Iron Homeostasis by Targeting Ferroportin Mondo/ChREBP-Mlx-Regulated Transcriptional Network Is Essential for Dietary Sugar Tolerance in Drosophila Mouse Oocyte Methylomes at Base Resolution Reveal Genome-Wide Accumulation of Non-CpG Methylation and Role of DNA Methyltransferases Mutations in LRRC50 Predispose Zebrafish and Humans to Seminomas Neutral Genomic Microevolution of a Recently Emerged Pathogen,Salmonella enterica Serovar Agona Npc1 Acting in Neurons and Glia Is Essential for the Formation and Maintenance of CNS Myelin Phosphorylation-Coupled Proteolysis of the Transcription Factor MYC2 Is Important for Jasmonate-Signaled Plant Immunity Reference-Free Population Genomics from Next-Generation Transcriptome Data and the Vertebrate-Invertebrate Gap Rod Monochromacy and the Coevolution of Cetacean Retinal Opsins RpoS Plays a Central Role in the SOS Induction by Sub-Lethal Aminoglycoside Concentrations in Vibrio cholerae Rtt109 Prevents Hyper-Amplification of Ribosomal RNA Genes through Histone Modification in Budding Yeast SNF5 Is an Essential Executor of Epigenetic Regulation during Differentiation Scavenger Receptors Mediate the Role of SUMO and Ftz-f1 in Drosophila Steroidogenesis Senataxin Plays an Essential Role with DNA Damage Response Proteins in Meiotic Recombination and Gene Silencing Sensory Neuron-Derived Eph Regulates Glomerular Arbors and Modulatory Function of a Central Serotonergic Neuron Sex-Differential Selection and the Evolution of X Inactivation Strategies Signatures of Diversifying Selection in European Pig Breeds Site-Specific Phosphorylation of the DNA Damage Response Mediator Rad9 by Cyclin-Dependent Kinases Regulates Activation of Checkpoint Kinase 1 Six Homeoproteins Directly Activate Myod Expression in the Gene Regulatory Networks That Control Early Myogenesis Smaug/SAMD4A Restores Translational Activity of CUGBP1 and Suppresses CUG-Induced Myopathy TIP48/Reptin and H2A.Z Requirement for Initiating Chromatin Remodeling in Estrogen-Activated Transcription Tbx2 Terminates Shh/Fgf Signaling in the Developing Mouse Limb Bud by Direct Repression of Gremlin1 The Chromosomal Passenger Protein Birc5b Organizes Microfilaments and Germ Plasm in the Zebrafish Embryo The Environment Affects Epistatic Interactions to Alter the Topology of an Empirical Fitness Landscape The G4 Genome The Genetic Correlation between Height and IQ: Shared Genes or Assortative Mating? The Genome Organization of Thermotoga maritima Reflects Its Lifestyle The Histone Demethylase Jarid1b Ensures Faithful Mouse Development by Protecting Developmental Genes from Aberrant H3K4me3 The Hourglass and the Early Conservation Models-Co-Existing Patterns of Developmental Constraints in Vertebrates The Quest for the Identification of Genetic Variants in Unexplained Cardiac Arrest and Idiopathic Ventricular Fibrillation The Tissue-Specific RNA Binding Protein T-STAR Controls Regional Splicing Patterns of Neurexin Pre-mRNAs in the Brain Tissue Homeostasis in the Wing Disc of Drosophila melanogaster: Immediate Response to Massive Damage during Development Transposable Elements Are Major Contributors to the Origin,Diversification,and Regulation of Vertebrate Long Noncoding RNAs