plos genetics سال:2013 - دوره:9

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plos genetics
سال:2013 - دوره:9 - شماره:6

A Genome-Wide,Fine-Scale Map of Natural Pigmentation Variation in Drosophila melanogaster A Six Months Exercise Intervention Influences the Genome-wide DNA Methylation Pattern in Human Adipose Tissue ABI4 Regulates Primary Seed Dormancy by Regulating the Biogenesis of Abscisic Acid and Gibberellins in Arabidopsis Altered Splicing of the BIN1 Muscle-Specific Exon in Humans and Dogs with Highly Progressive Centronuclear Myopathy BMS1 Is Mutated in Aplasia Cutis Congenita Breakage-fusion-bridge Cycles and Large Insertions Contribute to the Rapid Evolution of Accessory Chromosomes in a Fungal Pathogen Budding Yeast ATM/ATR Control Meiotic Double-Strand Break (DSB) Levels by Down-Regulating Rec114,an Essential Component of the DSB-machinery Causes and Consequences of Chromatin Variation between Inbred Mice Cohesin and Polycomb Proteins Functionally Interact to Control Transcription at Silenced and Active Genes Comparative Polygenic Analysis of Maximal Ethanol Accumulation Capacity and Tolerance to High Ethanol Levels of Cell Proliferation in Yeast Comprehensive High-Resolution Analysis of the Role of an Arabidopsis Gene Family in RNA Editing DNA Methylation Restricts Lineage-specific Functions of Transcription Factor Gata4 during Embryonic Stem Cell Differentiation DeepSAGE Reveals Genetic Variants Associated with Alternative Polyadenylation and Expression of Coding and Non-coding Transcripts Deregulation of the Protocadherin Gene FAT1 Alters Muscle Shapes: Implications for the Pathogenesis of Facioscapulohumeral Dystrophy Distinct Neuroblastoma-associated Alterations of PHOX2B Impair Sympathetic Neuronal Differentiation in Zebrafish Models Distinct and Atypical Intrinsic and Extrinsic Cell Death Pathways between Photoreceptor Cell Types upon Specific Ablation of Ranbp2 in Cone Photoreceptors Distinctive Expansion of Potential Virulence Genes in the Genome of the Oomycete Fish Pathogen Saprolegnia parasitica Disturbed Local Auxin Homeostasis Enhances Cellular Anisotropy and Reveals Alternative Wiring of Auxin-ethylene Crosstalk in Brachypodium distachyon Seminal Roots Drosophila Distal-less and Rotund Bind a Single Enhancer Ensuring Reliable and Robust bric-a-brac2 Expression in Distinct Limb Morphogenetic Fields Effectively Identifying eQTLs from Multiple Tissues by Combining Mixed Model and Meta-analytic Approaches Enterococcus faecalis Prophage Dynamics and Contributions to Pathogenic Traits Environmental Dependence of Genetic Constraint Evidence for Two Different Regulatory Mechanisms Linking Replication and Segregation of Vibrio cholerae Chromosome II Extensive Intra-Kingdom Horizontal Gene Transfer Converging on a Fungal Fructose Transporter Gene Fragile DNA Motifs Trigger Mutagenesis at Distant Chromosomal Loci in Saccharomyces cerevisiae From Many,One: Genetic Control of Prolificacy during Maize Domestication Functional Analysis of Neuronal MicroRNAs in Caenorhabditis elegans Dauer Formation by Combinational Genetics and Neuronal miRISC Immunoprecipitation Genetic Architecture of Vitamin B12 and Folate Levels Uncovered Applying Deeply Sequenced Large Datasets Genome-scale Analysis of Escherichia coli FNR Reveals Complex Features of Transcription Factor Binding Global DNA Hypermethylation in Down Syndrome Placenta H-NS Can Facilitate Specific DNA-binding by RNA Polymerase in AT-rich Gene Regulatory Regions H3.3-H4 Tetramer Splitting Events Feature Cell-Type Specific Enhancers Heritable Change Caused by Transient Transcription Errors High Trans-ethnic Replicability of GWAS Results Implies Common Causal Variants Histone Acetyl Transferase 1 Is Essential for Mammalian Development,Genome Stability,and the Processing of Newly Synthesized Histones H3 and H4 Hooked and Cooked: A Fish Killer Genome Exposed Horizontally Acquired Glycosyltransferase Operons Drive Salmonellae Lipopolysaccharide Diversity How Cool Is That: An Interview with Caroline Dean Impact of Natural Genetic Variation on Gene Expression Dynamics Inferring Demographic History from a Spectrum of Shared Haplotype Lengths Integrated Transcriptomic and Epigenomic Analysis of Primary Human Lung Epithelial Cell Differentiation Integrative Omics-Approach Discovers Dynamic and Regulatory Features of Bacterial Stress Responses Juvenile Hormone and Insulin Regulate Trehalose Homeostasis in the Red Flour Beetle,Tribolium castaneum Latent Effects of Hsp90 Mutants Revealed at Reduced Expression Levels Loss of Catalytically Inactive Lipid Phosphatase Myotubularin-related Protein 12 Impairs Myotubularin Stability and Promotes Centronuclear Myopathy in Zebrafish Meiosis-Specific Stable Binding of Augmin to Acentrosomal Spindle Poles Promotes Biased Microtubule Assembly in Oocytes Methylation of Histone H3 on Lysine 79 Associates with a Group of Replication Origins and Helps Limit DNA Replication Once per Cell Cycle Multi-organ Abnormalities and mTORC1 Activation in Zebrafish Model of Multiple Acyl-CoA Dehydrogenase Deficiency Multiplexin Promotes Heart but Not Aorta Morphogenesis by Polarized Enhancement of Slit/Robo Activity at the Heart Lumen Mutations in CERS3 Cause Autosomal Recessive Congenital Ichthyosis in Humans NSAIDs Modulate Clonal Evolution in Barrett's Esophagus Negative Regulation of Notch Signaling by Xylose Negative Regulation of the Novel norpAP24 Suppressor,diehard4,in the Endo-lysosomal Trafficking Underlies Photoreceptor Cell Degeneration Network Topologies and Convergent Aetiologies Arising from Deletions and Duplications Observed in Individuals with Autism Neuronal Target Identification Requires AHA-1-Mediated Fine-Tuning of Wnt Signaling in C. elegans PARP-1 Regulates Metastatic Melanoma through Modulation of Vimentin-induced Malignant Transformation Pervasive Transcription of the Human Genome Produces Thousands of Previously Unidentified Long Intergenic Noncoding RNAs RSR-2,the Caenorhabditis elegans Ortholog of Human Spliceosomal Component SRm300/SRRM2,Regulates Development by Influencing the Transcriptional Machinery SPO11-Independent DNA Repair Foci and Their Role in Meiotic Silencing Saccharomyces cerevisiae DNA Ligase IV Supports Imprecise End Joining Independently of Its Catalytic Activity Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits Survival Response to Increased Ceramide Involves Metabolic Adaptation through Novel Regulators of Glycolysis and Lipolysis The Gene Desert Mammary Carcinoma Susceptibility Locus Mcs1a Regulates Nr2f1 Modifying Mammary Epithelial Cell Differentiation and Proliferation The Genome of Tolypocladium inflatum: Evolution,Organization,and Expression of the Cyclosporin Biosynthetic Gene Cluster The Identification of Trans-acting Factors That Regulate the Expression of GDF5 via the Osteoarthritis Susceptibility SNP rs143383 The NADPH Metabolic Network Regulates Human αB-crystallin Cardiomyopathy and Reductive Stress in Drosophila melanogaster The RNA Export Factor,Nxt1,Is Required for Tissue Specific Transcriptional Regulation Transcriptome-Wide Mapping of 5-methylcytidine RNA Modifications in Bacteria,Archaea,and Yeast Reveals m5C within Archaeal mRNAs USF1 and hSET1A Mediated Epigenetic Modifications Regulate Lineage Differentiation and HoxB4 Transcription