|
|
|
|
Budding Yeast ATM/ATR Control Meiotic Double-Strand Break (DSB) Levels by Down-Regulating Rec114,an Essential Component of the DSB-machinery
|
|
|
|
|
|
|
|
نویسنده
|
carballo j.a. ,panizza s. ,serrentino m.e. ,johnson a.l. ,geymonat m. ,borde v. ,klein f. ,cha r.s.
|
|
منبع
|
plos genetics - 2013 - دوره : 9 - شماره : 6
|
|
چکیده
|
An essential feature of meiosis is spo11 catalysis of programmed dna double strand breaks (dsbs). evidence suggests that the number of dsbs generated per meiosis is genetically determined and that this ability to maintain a pre-determined dsb level,or dsb homeostasis
|
|
کلیدواژه
|
might be a property of the meiotic program. Here
|
|
آدرس
|
department of life sciences,genome damage and stability centre,university of sussex,falmer,united kingdom,division of stem cell biology and developmental genetics,mrc national institute for medical research,london, United Kingdom, department of chromosome biology,max f. perutz laboratories,university of vienna,dr. bohr-gasse 1,vienna,austria,(imba) institute of molecular biotechnology of the austrian academy of sciences,dr. bohr-gasse,vienna, Austria, cnrs umr218,institut curie/centre de recherche,umr218,pavillon pasteur,paris, France, division of stem cell biology and developmental genetics,mrc national institute for medical research,london, United Kingdom, the gurdon institute,university of cambridge,cambridge, United Kingdom, cnrs umr218,institut curie/centre de recherche,umr218,pavillon pasteur,paris, France, department of chromosome biology,max f. perutz laboratories,university of vienna,dr. bohr-gasse 1,vienna, Austria, department of life sciences,genome damage and stability centre,university of sussex,falmer,united kingdom,division of stem cell biology and developmental genetics,mrc national institute for medical research,london, United Kingdom
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Authors
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|