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plos genetics
  
سال:2013 - دوره:9 - شماره:8
  
 
A Critical Function of Mad2l2 in Primordial Germ Cell Development of Mice
  
 
A Flexible Approach for the Analysis of Rare Variants Allowing for a Mixture of Effects on Binary or Quantitative Traits
  
 
A Highly Redundant Gene Network Controls Assembly of the Outer Spore Wall in S. cerevisiae
  
 
A Model-Based Analysis of GC-Biased Gene Conversion in the Human and Chimpanzee Genomes
  
 
A Nuclear Calcium-Sensing Pathway Is Critical for Gene Regulation and Salt Stress Tolerance in Arabidopsis
  
 
A Recessive Founder Mutation in Regulator of Telomere Elongation Helicase 1,RTEL1,Underlies Severe Immunodeficiency and Features of Hoyeraal Hreidarsson Syndrome
  
 
A Role for CF1A 3′ End Processing Complex in Promoter-Associated Transcription
  
 
ATM Release at Resected Double-Strand Breaks Provides Heterochromatin Reconstitution to Facilitate Homologous Recombination
  
 
An Essential Function for the ATR-Activation-Domain (AAD) of TopBP1 in Mouse Development and Cellular Senescence
  
 
Associations of Mitochondrial Haplogroups B4 and E with Biliary Atresia and Differential Susceptibility to Hydrophobic Bile Acid
  
 
Binding of TFIIIC to SINE Elements Controls the Relocation of Activity-Dependent Neuronal Genes to Transcription Factories
  
 
Brittle Culm1,a COBRA-Like Protein,Functions in Cellulose Assembly through Binding Cellulose Microfibrils
  
 
Calpain-6 Deficiency Promotes Skeletal Muscle Development and Regeneration
  
 
Cauli: A Mouse Strain with an Ift140 Mutation That Results in a Skeletal Ciliopathy Modelling Jeune Syndrome
  
 
Causal and Synthetic Associations of Variants in the SERPINA Gene Cluster with Alpha1-antitrypsin Serum Levels
  
 
Characterization of the p53 Cistrome - DNA Binding Cooperativity Dissects p53's Tumor Suppressor Functions
  
 
Chromatin Sampling-An Emerging Perspective on Targeting Polycomb Repressor Proteins
  
 
Chromosomal Copy Number Variation,Selection and Uneven Rates of Recombination Reveal Cryptic Genome Diversity Linked to Pathogenicity
  
 
Cited1 Deficiency Suppresses Intestinal Tumorigenesis
  
 
Combining Quantitative Genetic Footprinting and Trait Enrichment Analysis to Identify Fitness Determinants of a Bacterial Pathogen
  
 
Comparative Anatomy of Chromosomal Domains with Imprinted and Non-Imprinted Allele-Specific DNA Methylation
  
 
Comparative Genomic and Functional Analysis of 100 Lactobacillus rhamnosus Strains and Their Comparison with Strain GG
  
 
Comparative Oncogenomic Analysis of Copy Number Alterations in Human and Zebrafish Tumors Enables Cancer Driver Discovery
  
 
Computational Identification of Diverse Mechanisms Underlying Transcription Factor-DNA Occupancy
  
 
Cross-Species Array Comparative Genomic Hybridization Identifies Novel Oncogenic Events in Zebrafish and Human Embryonal Rhabdomyosarcoma
  
 
Deletion of microRNA-80 Activates Dietary Restriction to Extend C. elegans Healthspan and Lifespan
  
 
Depletion of Retinoic Acid Receptors Initiates a Novel Positive Feedback Mechanism that Promotes Teratogenic Increases in Retinoic Acid
  
 
Distinct SUMO Ligases Cooperate with Esc2 and Slx5 to Suppress Duplication-Mediated Genome Rearrangements
  
 
Dynamic Rewiring of the Drosophila Retinal Determination Network Switches Its Function from Selector to Differentiation
  
 
Endogenous Stress Caused by Faulty Oxidation Reactions Fosters Evolution of 2,4-Dinitrotoluene-Degrading Bacteria
  
 
Fifty Years On: GWAS Confirms the Role of a Rare Variant in Lung Disease
  
 
Functional Characterisation of Alpha-Galactosidase A Mutations as a Basis for a New Classification System in Fabry Disease
  
 
GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm
  
 
Gene Expression Regulation by Upstream Open Reading Frames and Human Disease
  
 
Generation of Tandem Direct Duplications by Reversed-Ends Transposition of Maize Ac Elements
  
 
Genetic Circuits that Govern Bisexual and Unisexual Reproduction in Cryptococcus neoformans
  
 
Genetic Mapping of Specific Interactions between Aedes aegypti Mosquitoes and Dengue Viruses
  
 
Genic Intolerance to Functional Variation and the Interpretation of Personal Genomes
  
 
Genome Wide Association Identifies Novel Loci Involved in Fungal Communication
  
 
Genome-Wide Association of Body Fat Distribution in African Ancestry Populations Suggests New Loci
  
 
Genome-Wide DNA Methylation Analysis of Systemic Lupus Erythematosus Reveals Persistent Hypomethylation of Interferon Genes and Compositional Changes to CD4+ T-cell Populations
  
 
Global Analysis of Fission Yeast Mating Genes Reveals New Autophagy Factors
  
 
Global Analysis of the Sporulation Pathway of Clostridium difficile
  
 
H2A.Z Acidic Patch Couples Chromatin Dynamics to Regulation of Gene Expression Programs during ESC Differentiation
  
 
Hard Selective Sweep and Ectopic Gene Conversion in a Gene Cluster Affording Environmental Adaptation
  
 
High-Throughput Genetic and Gene Expression Analysis of the RNAPII-CTD Reveals Unexpected Connections to SRB10/CDK8
  
 
Histone Variant HTZ1 Shows Extensive Epistasis with,but Does Not Increase Robustness to,New Mutations
  
 
Identification of DSB-1,a Protein Required for Initiation of Meiotic Recombination in Caenorhabditis elegans,Illuminates a Crossover Assurance Checkpoint
  
 
In Vivo Bypass of 8-oxodG
  
 
Integrated Model of De Novo and Inherited Genetic Variants Yields Greater Power to Identify Risk Genes
  
 
Integrative Modeling of eQTLs and Cis-Regulatory Elements Suggests Mechanisms Underlying Cell Type Specificity of eQTLs
  
 
Introns Regulate Gene Expression in Cryptococcus neoformans in a Pab2p Dependent Pathway
  
 
Loss of a Conserved tRNA Anticodon Modification Perturbs Cellular Signaling
  
 
Masculinization of Gene Expression Is Associated with Exaggeration of Male Sexual Dimorphism
  
 
Masculinization of the X Chromosome in the Pea Aphid
  
 
Mediator Directs Co-transcriptional Heterochromatin Assembly by RNA Interference-Dependent and -Independent Pathways
  
 
Meiotic Recombination Initiation in and around Retrotransposable Elements in Saccharomyces cerevisiae
  
 
Myc-Driven Overgrowth Requires Unfolded Protein Response-Mediated Induction of Autophagy and Antioxidant Responses in Drosophila melanogaster
  
 
Neuronal Reprograming of Protein Homeostasis by Calcium-Dependent Regulation of the Heat Shock Response
  
 
Origin and Functional Diversification of an Amphibian Defense Peptide Arsenal
  
 
Past Visits Present: TCF/LEFs Partner with ATFs for β-Catenin-Independent Activity
  
 
QTL Analysis of High Thermotolerance with Superior and Downgraded Parental Yeast Strains Reveals New Minor QTLs and Converges on Novel Causative Alleles Involved in RNA Processing
  
 
Ras-Induced Changes in H3K27me3 Occur after Those in Transcriptional Activity
  
 
Ras1 Acts through Duplicated Cdc42 and Rac Proteins to Regulate Morphogenesis and Pathogenesis in the Human Fungal Pathogen Cryptococcus neoformans
  
 
Re-Ranking Sequencing Variants in the Post-GWAS Era for Accurate Causal Variant Identification
  
 
Recurrent Modification of a Conserved Cis-Regulatory Element Underlies Fruit Fly Pigmentation Diversity
  
 
Regulation of Sister Chromosome Cohesion by the Replication Fork Tracking Protein SeqA
  
 
Reversible and Rapid Transfer-RNA Deactivation as a Mechanism of Translational Repression in Stress
  
 
Sociogenomics of Cooperation and Conflict during Colony Founding in the Fire Ant Solenopsis invicta
  
 
Species and Population Level Molecular Profiling Reveals Cryptic Recombination and Emergent Asymmetry in the Dimorphic Mating Locus of C. reinhardtii
  
 
The Architecture of a Prototypical Bacterial Signaling Circuit Enables a Single Point Mutation to Confer Novel Network Properties
  
 
The C. elegans DSB-2 Protein Reveals a Regulatory Network that Controls Competence for Meiotic DSB Formation and Promotes Crossover Assurance
  
 
The Conditional Nature of Genetic Interactions: The Consequences of Wild-Type Backgrounds on Mutational Interactions in a Genome-Wide Modifier Screen
  
 
The Enhancer Landscape during Early Neocortical Development Reveals Patterns of Dense Regulation and Co-option
  
 
The Genome of Spraguea lophii and the Basis of Host-Microsporidian Interactions
  
 
The Innocence Project at Twenty: An Interview with Barry Scheck
  
 
The Intronic Long Noncoding RNA ANRASSF1 Recruits PRC2 to the RASSF1A Promoter,Reducing the Expression of RASSF1A and Increasing Cell Proliferation
  
 
The PSEN1,p.E318G Variant Increases the Risk of Alzheimer's Disease in APOE-ε4 Carriers
  
 
The Relative Contribution of Proximal 5′ Flanking Sequence and Microsatellite Variation on Brain Vasopressin 1a Receptor (Avpr1a) Gene Expression and Behavior
  
 
The Ribosomal Protein Rpl22 Controls Ribosome Composition by Directly Repressing Expression of Its Own Paralog,Rpl22l1
  
 
The Wilms Tumor Gene,Wt1,Is Critical for Mouse Spermatogenesis via Regulation of Sertoli Cell Polarity and Is Associated with Non-Obstructive Azoospermia in Humans
  
 
The Yeast Environmental Stress Response Regulates Mutagenesis Induced by Proteotoxic Stress
  
 
Transposon Domestication versus Mutualism in Ciliate Genome Rearrangements
  
 
Vitellogenin Underwent Subfunctionalization to Acquire Caste and Behavioral Specific Expression in the Harvester Ant Pogonomyrmex barbatus
  
 
β-Catenin-Independent Activation of TCF1/LEF1 in Human Hematopoietic Tumor Cells through Interaction with ATF2 Transcription Factors
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