plos genetics سال:2010 - دوره:6

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plos genetics
سال:2010 - دوره:6 - شماره:4

A Pax3/Dmrt2/Myf5 regulatory cascade functions at the onset of myogenesis A cis-regulatory signature for chordate anterior neuroectodermal genes A microarray-based genetic screen for yeast chronological aging factors Absence of evidence for MHC-dependent mate selection within HapMap populations Actin-related protein Arp6 influences H2A.Z-dependent and -independent gene expression and links ribosomal protein genes to nuclear pores Activation of estrogen-responsive genes does not require their nuclear co-localization Admixture mapping scans identify a locus affecting retinal vascular caliber in hypertensive African Americans: The Atherosclerosis Risk in Communities (ARIC) study Allele-specific virulence attenuation of the Pseudomonas syringae HopZ1a type III effector via the Arabidopsis ZAR1 resistance protein Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations Cdh11 acts as a tumor suppressor in a murine retinoblastoma model by facilitating tumor cell death Chromosome 9p21 SNPs associated with multiple disease phenotypes correlate with ANRIL expression Combined inactivation of pRB and Hippo pathways induces dedifferentiation in the Drosophila retina Cyclic expression of Lhx2 regulates hair formation De novo assembly of a 40 Mb eukaryotic genome from short sequence reads: Sordaria macrospora,a model organism for fungal morphogenesis Deletion of the WD40 domain of LRRK2 in zebrafish causes parkinsonism-like loss of neurons and locomotive defect Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development Down-regulation of honey bee IRS gene biases behavior toward food rich in protein Epigenetic regulation of a murine retrotransposon by a dual histone modification mark Fragile X mental retardation protein regulates proliferation and differentiation of adult neural stem/progenitor cells Fragilities caused by dosage imbalance in regulation of the budding yeast cell cycle GTPase activity plays a key role in the pathobiology of LRRK2 Genetic analysis of fin development in zebrafish identifies furin and Hemicentin1 as potential novel fraser syndrome disease genes Genetic evidence for hybrid trait speciation in Heliconius butterflies Genetic tests for ecological and allopatric speciation in anoles on an Island archipelago Genome-wide association study of Lp-PLA2 activity and mass in the framingham heart study Genome-wide patterns of adaptation to temperate environments associated with transposable elements in Drosophila Human telomeres are hypersensitive to UV-induced DNA damage and refractory to repair Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer Incipient balancing selection through adaptive loss of aquaporins in natural Saccharomyces cerevisiae populations MicroRNA-directed siRNA biogenesis in Caenorhabditis elegans Natural single-nucleosome epi-polymorphisms in yeast Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans Replication timing of human telomeres is chromosome arm-specific,influenced by subtelomeric structures and connected to nuclear localization S phase progression in human cells is dictated by the genetic continuity of DNA foci The TALE class homeobox gene Smed-prep defines the anterior compartment for head regeneration The five AHMTP1 zinc transporters undergo different evolutionary fates towards adaptive evolution to zinc tolerance in Arabidopsis halleri The next generation becomes the now generation Trait-associated SNPs are more likely to be eQTLs: Annotation to enhance discovery from GWAS Two new loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and German study groups Whole-genome SNP association in the horse: Identification of a deletion in myosin Va responsible for Lavender Foal Syndrome