plos genetics سال:2010 - دوره:6

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plos genetics
سال:2010 - دوره:6 - شماره:10

A novel adaptive method for the analysis of next-generation sequencing data to detect complex trait associations with rare variants due to gene main effects and interactions - صفحه:1-14 Actin depolymerizing factors cofilin1 and destrin are required for ureteric bud branching morphogenesis - صفحه:1-11 Allele-specific down-regulation of RPTOR expression induced by retinoids contributes to climate adaptations - صفحه:1-10 Altering a histone H3K4 methylation pathway in glomerular podocytes promotes a chronic disease phenotype - صفحه:1-15 Alternative splicing at a NAGNAG acceptor site as a novel phenotype modifier - صفحه:1-11 Ancient and recent adaptive evolution of primate non-homologous end joining genes - صفحه:1-12 Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation - صفحه:1-13 Characterising and predicting haploinsufficiency in the human genome - صفحه:1-11 Characterization of LINE-1 ribonucleoprotein particles - صفحه:1-19 Common genetic variants and modification of penetrance of BRCA2-associated breast cancer - صفحه:1-12 Comprehensive analysis reveals dynamic and evolutionary plasticity of Rab GTPases and membrane traffic in Tetrahymena thermophila - صفحه:1-18 Conjugative DNA transfer induces the bacterial SOS response and promotes antibiotic resistance development through integron activation - صفحه:1-10 Conserved genes act as modifiers of invertebrate SMN loss of function defects - صفحه:1-16 Continuous requirement for the Clr4 complex but not RNAi for centromeric heterochromatin assembly in fission yeast harboring a disrupted RITS complex - صفحه:1-16 DSIF and RNA polymerase II CTD phosphorylation coordinate the recruitment of Rpd3S to actively transcribed genes - صفحه:1-12 Dual functions of ASCIZ in the DNA base damage response and pulmonary organogenesis - صفحه:1-13 Evidence for a Xer/dif system for chromosome resolution in archaea - صفحه:1-11 FSHD: A repeat contraction disease finally ready to expand (our understanding of its pathogenesis) - صفحه:1-3 Facioscapulohumeral dystrophy: Incomplete suppression of a retrotransposed gene - صفحه:1-14 Four novel loci (19q13,6q24,12q24,and 5q14) influence the microcirculation In vivo - صفحه:1-12 Genetic association study identifies HSPB7 as a risk gene for idiopathic dilated cardiomyopathy - صفحه:1-9 Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension - صفحه:1-11 Genome-wide identification of targets and function of individual microRNAs in mouse embryonic stem cells - صفحه:1-13 Gimap3 regulates tissue-specific mitochondrial DNA segregation - صفحه:1-9 H3K27me3 profiling of the endosperm implies exclusion of polycomb group protein targeting by DNA methylation - صفحه:1-14 Lifespan extension by preserving proliferative homeostasis in Drosophila - صفحه:1-15 Loss of the p53/p63 regulated desmosomal protein perp promotes tumorigenesis - صفحه:1-16 Nasty viruses,costly plasmids,population dynamics,and the conditions for establishing and maintaining CRISPR-mediated adaptive immunity in bacteria - صفحه:1-12 Pervasive cryptic epistasis in molecular evolution - صفحه:1-10 Role for the mammalian Swi5-Sfr1 complex in DNA strand break repair through homologous recombination - صفحه:1-11 Simultaneous disruption of two DNA polymerases,Polη and Polζ,in avian DT40 cells unmasks the role of Polη in cellular response to various DNA lesions - صفحه:1-13 Stress-induced activation of heterochromatic transcription - صفحه:1-11 The De novo cytosine methyltransferase DRM2 requires intact UBA domains and a catalytically mutated paralog DRM3 during RNA-directed DNA methylation in arabidopsis thaliana - صفحه:1-11 The meiotic recombination checkpoint suppresses NHK-1 kinase to prevent reorganisation of the oocyte nucleus in Drosophila - صفحه:1-10 Tight regulation of the intS Gene of the KplE1 prophage: A new paradigm for integrase gene regulation - صفحه:1-15 Transition from positive to neutral in mutation fixation along with continuing rising fitness in thermal adaptive evolution - صفحه:1-10 β-Actin and γ-Actin are each dispensable for auditory hair cell development but required for stereocilia maintenance - صفحه:1-12