plos genetics سال:2011 - دوره:7

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plos genetics
سال:2011 - دوره:7 - شماره:2

A genome-wide study of DNA methylation patterns and gene expression levels in multiple human and chimpanzee tissues A new testing strategy to identify rare variants with either risk or protective effect on disease A population genetic approach to mapping neurological disorder genes using deep resequencing A study of CNVS as trait-associated polymorphisms and as expression quantitative trait loci AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: The complex nature of genetic association through growth and development Break to make a connection CSP and takeout genes modulate the switch between attraction and repulsion during behavioral phase change in the migratory locust Characterization of transcriptome remodeling during cambium formation identifies MOL1 and RUL1 as opposing regulators of secondary growth Correlated evolution of nearby residues in drosophilid proteins Drosophila lipophorin receptors mediate the uptake of neutral lipids in oocytes and imaginal disc cells by an endocytosis-independent mechanism Epistatic interaction Maps relative to multiple metabolic phenotypes Genome-Wide association study of coronary heart disease and its risk factors in 8,090 african americans: The nhlbi CARe project Genome-wide association of familial late-onset alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE Genome-wide association studies of the PR interval in African Americans Genome-wide transcript profiling of endosperm without paternal contribution identifies parent-of-origin-dependent regulation of AGAMOUS-LIKE36 Mapping a new spontaneous preterm birth susceptibility gene,IGF1R,using linkage,haplotype sharing,and association analysis Mapping of the disease locus and identification of ADAMTS10 as a candidate gene in a canine model of primary open angle Glaucoma Meta-analysis of genome-wide association studies in celiac disease and rheumatoid arthritis identifies fourteen non-HLA shared loci MiRNA control of vegetative phase change in trees Mutations in zebrafish Lrp2 result in adult-onset ocular pathogenesis that models myopia and other risk factors for glaucoma New functions of Ctf18-RFC in preserving genome stability outside its role in sister chromatid cohesion Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance Parallel evolution of a type IV secretion system in radiating lineages of the host-restricted bacterial pathogen bartonella Pathogenic VCP/TER94 alleles are dominant actives and contribute to neurodegeneration by altering cellular ATP level in a drosophila IBMPFD model Pervasive adaptive protein evolution apparent in diversity patterns around amino acid substitutions in drosophila simulans Phosphoinositide regulation of integrin trafficking required for muscle attachment and maintenance Prevalence of epistasis in the evolution of influenza A surface proteins Quantitative models of the mechanisms that control genome-wide patterns of transcription factor binding during early drosophila development Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes Single-tissue and cross-tissue heritability of gene expression via identity-by-descent in related or unrelated individuals Srf1 is a novel regulator of phospholipase D activity and is essential to buffer the toxic effects of C16:0 platelet activating factor Targeted sister chromatid cohesion by sir2 The architecture of gene regulatory variation across multiple human tissues: The muTHER study The cardiac transcription network modulated by gata4,mef2a,nkx2.5,srf,histone modifications,and microRNAs The drosophila zinc finger protein trade embargo is required for double strand break formation in meiosis The evolution of host specialization in the vertebrate gut symbiont Lactobacillus reuteri The genome sequence of the leaf-cutter ant Atta cephalotes reveals insights into its obligate symbiotic lifestyle Two frizzled planar cell polarity signals in the drosophila wing are differentially organized by the fat/dachsous pathway Whole-genome comparison reveals novel genetic elements that characterize the genome of industrial strains of saccharomyces cerevisiae [SWI+],the prion formed by the chromatin remodeling factor Swi1,is highly sensitive to alterations in hsp70 chaperone system activity