plos genetics سال:2011 - دوره:7

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plos genetics
سال:2011 - دوره:7 - شماره:11

A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and smoothened Activation of Bmp2-Smad1 signal and its regulation by coordinated alteration of H3K27 trimethylation in Ras-induced senescence Arabidopsis homologs of retinoblastoma-associated protein 46/48 associate with a histone deacetylase to act redundantly in chromatin silencing Attenuation of the sensing capabilities of PhoQ in transition to obligate insect-bacterial association Caenorhabditis elegans cyclin D/CDK4 and cyclin E/CDK2 induce distinct cell cycle re-entry programs in differentiated muscle cells Capture of microRNA-bound mRNAs identifies the tumor suppressor miR-34a as a regulator of growth factor signaling Consequences of eukaryotic enhancer architecture for gene expression dynamics,development,and fitness De novo origin of human protein-coding genes De novo origins of human genes Distinct genetic architectures for male and female inflorescence traits of maize Drosophila duplication hotspots are associated with late-replicating regions of the genome Effect of host species on the distribution of mutational fitness effects for an RNA virus Evidence-based annotation of gene function in Shewanella oneidensis MR-1 using genome-wide fitness profiling across 121 conditions FOXO regulates organ-specific phenotypic plasticity in Drosophila For male Caenorhabditis elegans,sperm activation is a Just-in-time event Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence Genetic interaction maps in Escherichia coli reveal functional crosstalk among cell envelope biogenesis pathways Genome-wide crossover distribution in Arabidopsis thaliana meiosis reveals sex-specific patterns along chromosomes Heritable epigenetic variation among maize inbreds Histone H3K56 acetylation,CAF1,and Rtt106 coordinate nucleosome assembly and stability of advancing replication forks Multiple means to the same end: The genetic basis of acquired stress resistance in yeast Over-expression of DSCAM and COL6A2 cooperatively generates congenital heart defects PBX1 genomic pioneer function drives ERα signaling underlying progression in breast cancer PcG complexes set the stage for epigenetic inheritance of gene silencing in early S phase before replication Pch2 acts through Xrs2 and Tel1/ATM to modulate interhomolog bias and checkpoint function during meiosis Physiological IRE-1-XBP-1 and PEK-1 signaling in Caenorhabditis elegans larval development and immunity Recessive antimorphic alleles overcome functionally redundant loci to reveal TSO1 function in Arabidopsis flowers and meristems Relative burden of large CNVs on a range of neurodevelopmental phenotypes Role of Pirh2 in mediating the regulation of p53 and c-Myc SOX9 governs differentiation stage-specific gene expression in growth plate chondrocytes via direct concomitant transactivation and repression Serratia symbiotica from the aphid Cinara cedri: A missing link from facultative to obligate insect endosymbiont Short day-mediated cessation of growth requires the downregulation of AINTEGUMENTALIKE1 transcription factor in hybrid aspen Signatures of environmental genetic adaptation pinpoint pathogens as the main selective pressure through human evolution TRY-5 is a sperm-activating protease in Caenorhabditis elegans seminal fluid The ERI-6/7 helicase acts at the first stage of an siRNA amplification pathway that targets recent gene duplications The NF1 gene contains hotspots for L1 endonuclease-dependent De Novo insertion The SUN protein Mps3 is required for spindle pole body insertion into the nuclear membrane and nuclear envelope homeostasis