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Partial response to anakinra in life-threatening Henoch-Schönlein purpura: Case report
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نویسنده
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boyer e.m. ,turman m. ,o'neil k.m.
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منبع
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pediatric rheumatology - 2011 - دوره : 9 - شماره : 0
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چکیده
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Henoch-schönlein purpura is one of the most common forms of systemic vasculitis of childhood. we report the response to anakinra,the interleukin-1 receptor antagonist,in a 9 year old girl without prior medical problems who developed life-threatening henoch-schönlein vasculitis that produced renal failure,pulmonary hemorrhage and vasculitis of the brain. her response supports the theory that interleukin-1 may be an important mediator in this disease. further study of interleukin-1 antagonists in severe henoch-schönlein purpura may be warranted. © 2011 boyer et al; licensee biomed central ltd.
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آدرس
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division of rheumatology,department of pediatrics,university of oklahoma health sciences center,oklahoma city,ok, United States, division of nephrology department of pediatrics,university of oklahoma health sciences center,oklahoma city,ok, United States, division of rheumatology,department of pediatrics,university of oklahoma health sciences center,oklahoma city,ok, United States
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Authors
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