Chorea,a little-known manifestation in systemic lupus erythematosus: Short literature review and four case reports

Chorea is a movement disorder that may be found in children due to several causes. here we focus especially on systemic lupus erythematosus associated chorea. first we outline its epidemiology,hypothesized pathogenesis,clinical presentation and treatment,then we report four significant clinical cases,which represent well the extreme variability of set of symptoms that may accompany lupus chorea. our experience,according to literature,suggests that choreic movements in a child should alert the pediatrician and lead him to investigate a potential neurological involvement of systemic lupus erythematosus. © 2013 torreggiani et al.; licensee biomed central ltd.