plos pathogens سال:2015 - دوره:11

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plos pathogens
سال:2015 - دوره:11 - شماره:7

A Comprehensive Analysis of Replicating Merkel Cell Polyomavirus Genomes Delineates the Viral Transcription Program and Suggests a Role for mcv-miR-M1 in Episomal Persistence A Novel Antiviral Target Structure Involved in the RNA Binding,Dimerization,and Nuclear Export Functions of the Influenza A Virus Nucleoprotein A Unique Human Norovirus Lineage with a Distinct HBGA Binding Interface Activation of TLR2 and TLR6 by Dengue NS1 Protein and Its Implications in the Immunopathogenesis of Dengue Virus Infection Age-Dependent Cell Trafficking Defects in Draining Lymph Nodes Impair Adaptive Immunity and Control of West Nile Virus Infection An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression An Internally Translated MAVS Variant Exposes Its Amino-terminal TRAF-Binding Motifs to Deregulate Interferon Induction Analysis of the SUMO2 Proteome during HSV-1 Infection Basic Prion Science “Spreads” Insight CR3 and Dectin-1 Collaborate in Macrophage Cytokine Response through Association on Lipid Rafts and Activation of Syk-JNK-AP-1 Pathway Calprotectin Increases the Activity of the SaeRS Two Component System and Murine Mortality during Staphylococcus aureus Infections Capacity of Broadly Neutralizing Antibodies to Inhibit HIV-1 Cell-Cell Transmission Is Strain- and Epitope-Dependent Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary,Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein Correction to: Transgenic Fatal Familial Insomnia Mice Indicate Prion Infectivity-Independent Mechanisms of Pathogenesis and Phenotypic Expression of Disease (PLoS Pathog,(2015) 11,[7]) Correction: Granulocytes Impose a Tight Bottleneck upon the Gut Luminal Pathogen Population during Salmonella Typhimurium Colitis ((2015),11,7) Cross Kingdom Activators of Five Classes of Bacterial Effectors Decline of FoxP3+ Regulatory CD4 T Cells in Peripheral Blood of Children Heavily Exposed to Malaria Deploying FLAREs to Visualize Functional Outcomes of Host—Pathogen Encounters Dimerization-Induced Allosteric Changes of the Oxyanion-Hole Loop Activate the Pseudorabies Virus Assemblin pUL26N,a Herpesvirus Serine Protease EhVps32 Is a Vacuole-Associated Protein Involved in Pinocytosis and Phagocytosis of Entamoeaba histolytica Epstein-Barr Virus Proteins EBNA3A and EBNA3C Together Induce Expression of the Oncogenic MicroRNA Cluster miR-221/miR-222 and Ablate Expression of Its Target p57KIP2 Evaluating Human T-Cell Therapy of Cytomegalovirus Organ Disease in HLA-Transgenic Mice Existing Infection Facilitates Establishment and Density of Malaria Parasites in Their Mosquito Vector Exploiting Fungal Virulence-Regulating Transcription Factors As Novel Antifungal Drug Targets Expression of the Blood-Group-Related Gene B4galnt2 Alters Susceptibility to Salmonella Infection Extracellular Virions: The Advance Guard of Poxvirus Infections HIV Reactivation from Latency after Treatment Interruption Occurs on Average Every 5-8 Days—Implications for HIV Remission Herpesvirus Genome Recognition Induced Acetylation of Nuclear IFI16 Is Essential for Its Cytoplasmic Translocation,Inflammasome and IFN-β Responses Human Enterovirus Nonstructural Protein 2CATPase Functions as Both an RNA Helicase and ATP-Independent RNA Chaperone IFNγ and IL-12 Restrict Th2 Responses during Helminth/Plasmodium Co-Infection and Promote IFNγ from Th2 Cells IL-27 Signaling Is Crucial for Survival of Mice Infected with African Trypanosomes via Preventing Lethal Effects of CD4+ T Cells and IFN-γ Identification of Caspase Cleavage Sites in KSHV Latency-Associated Nuclear Antigen and Their Effects on Caspase-Related Host Defense Responses Intraperitoneal Infection of Wild-Type Mice with Synthetically Generated Mammalian Prion K-bZIP Mediated SUMO-2/3 Specific Modification on the KSHV Genome Negatively Regulates Lytic Gene Expression and Viral Reactivation Latent KSHV Infected Endothelial Cells Are Glutamine Addicted and Require Glutaminolysis for Survival Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to Integration Macrophages Subvert Adaptive Immunity to Urinary Tract Infection Mechanisms of Host Behavioral Change in Toxoplasma gondii Rodent Association MiR-21 in Extracellular Vesicles Leads to Neurotoxicity via TLR7 Signaling in SIV Neurological Disease Mosquitoes Reset Malaria Parasites Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer Lesions N-acetylglucosamine Regulates Virulence Properties in Microbial Pathogens Neuronal Interferon Signaling Is Required for Protection against Herpes Simplex Virus Replication and Pathogenesis On and Under the Skin: Emerging Basidiomycetous Yeast Infections Caused by Trichosporon Species Periodontal Diseases: Bug Induced,Host Promoted Phenylbutyrate Is Bacteriostatic against Mycobacterium tuberculosis and Regulates the Macrophage Response to Infection,Synergistically with 25-Hydroxy-Vitamin D₃ Phosphoproteomic Analysis of KSHV-Infected Cells Reveals Roles of ORF45-Activated RSK during Lytic Replication RNA Virus Reassortment: An Evolutionary Mechanism for Host Jumps and Immune Evasion Rapidly Evolving Genes Are Key Players in Host Specialization and Virulence of the Fungal Wheat Pathogen Zymoseptoria tritici (Mycosphaerella graminicola) Research Driven by Curiosity: The Journey from Basic Molecular Biology and Virology to Studies of Human Pathogenic Coronaviruses Risks of Antibiotic Exposures Early in Life on the Developing Microbiome Should Symbionts Be Nice or Selfish? Antiviral Effects of Wolbachia Are Costly but Reproductive Parasitism Is Not Staphylococcus aureus Colonization of the Mouse Gastrointestinal Tract Is Modulated by Wall Teichoic Acid,Capsule,and Surface Proteins Suppression of Long-Lived Humoral Immunity Following Borrelia burgdorferi Infection Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate,PEP005,Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation THY-1 Cell Surface Antigen (CD90) Has an Important Role in the Initial Stage of Human Cytomegalovirus Infection The Broad Neutralizing Antibody Responses after HIV-1 Superinfection Are Not Dominated by Antibodies Directed to Epitopes Common in Single Infection The DSF Family of Cell–Cell Signals: An Expanding Class of Bacterial Virulence Regulators The Emerging Role for RNA Polymerase II in Regulating Virulence Gene Expression in Malaria Parasites The Endosymbiotic Bacterium Wolbachia Selectively Kills Male Hosts by Targeting the Masculinizing Gene The Lung Microbiome: New Principles for Respiratory Bacteriology in Health and Disease The Role of VP1 Amino Acid Residue 145 of Enterovirus 71 in Viral Fitness and Pathogenesis in a Cynomolgus Monkey Model The Serine Protease EspC from Enteropathogenic Escherichia coli Regulates Pore Formation and Cytotoxicity Mediated by the Type III Secretion System Transfer of Immunity from Mother to Offspring Is Mediated via Egg-Yolk Protein Vitellogenin Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS Turning Up the Heat: Inflammasome Activation by Fungal Pathogens Type VI Secretion System Transports Zn2+ to Combat Multiple Stresses and Host Immunity Ubiquilin 1 Promotes IFN-γ-Induced Xenophagy of Mycobacterium tuberculosis Utilizing Chemical Genomics to Identify Cytochrome b as a Novel Drug Target for Chagas Disease Vaccination Drives Changes in Metabolic and Virulence Profiles of Streptococcus pneumoniae Virulence of Group A Streptococci Is Enhanced by Human Complement Inhibitors Vpr Promotes Macrophage-Dependent HIV-1 Infection of CD4+ T Lymphocytes Vpu Exploits the Cross-Talk between BST2 and the ILT7 Receptor to Suppress Anti-HIV-1 Responses by Plasmacytoid Dendritic Cells α2-Macroglobulin Can Crosslink Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Molecules and May Facilitate Adhesion of Parasitized Erythrocytes