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The Ancient Evolutionary History of Polyomaviruses
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نویسنده
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buck c.b. ,van doorslaer k. ,peretti a. ,geoghegan e.m. ,tisza m.j. ,an p. ,katz j.p. ,pipas j.m. ,mcbride a.a. ,camus a.c. ,mcdermott a.j. ,dill j.a. ,delwart e. ,ng t.f.f. ,farkas k. ,austin c. ,kraberger s. ,davison w. ,pastrana d.v. ,varsani a.
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منبع
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plos pathogens - 2016 - دوره : 12 - شماره : 4
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چکیده
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Polyomaviruses are a family of dna tumor viruses that are known to infect mammals and birds. to investigate the deeper evolutionary history of the family,we used a combination of viral metagenomics,bioinformatics,and structural modeling approaches to identify and characterize polyomavirus sequences associated with fish and arthropods. analyses drawing upon the divergent new sequences indicate that polyomaviruses have been gradually co-evolving with their animal hosts for at least half a billion years. phylogenetic analyses of individual polyomavirus genes suggest that some modern polyomavirus species arose after ancient recombination events involving distantly related polyomavirus lineages. the improved evolutionary model provides a useful platform for developing a more accurate taxonomic classification system for the viral family polyomaviridae.
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آدرس
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lab of cellular oncology,nci,nih,bethesdamd, United States, lab of viral diseases,niaid,nih,bethesdamd, United States, lab of cellular oncology,nci,nih,bethesdamd, United States, lab of cellular oncology,nci,nih,bethesdamd, United States, lab of cellular oncology,nci,nih,bethesdamd, United States, department of biological sciences,university of pittsburgh,pittsburgh,pa, United States, department of biological sciences,university of pittsburgh,pittsburgh,pa, United States, department of biological sciences,university of pittsburgh,pittsburgh,pa, United States, lab of viral diseases,niaid,nih,bethesdamd, United States, department of pathology,university of georgia,athens,ga, United States, animal health department,georgia aquarium,inc,atlanta,ga, United States, department of pathology,university of georgia,athens,ga, United States, blood systems research institute,san francisco,ca,united states,department of laboratory medicine,university of california,san francisco,san francisco,ca, United States, blood systems research institute,san francisco,ca,united states,department of laboratory medicine,university of california,san francisco,san francisco,ca,united states,dvd,ncird,centers for disease control,atlanta,ga, United States, school of biological sciences,university of canterbury,christchurch, New Zealand, school of biological sciences,university of canterbury,christchurch, New Zealand, school of biological sciences,university of canterbury,christchurch, New Zealand, school of biological sciences,university of canterbury,christchurch, New Zealand, lab of cellular oncology,nci,nih,bethesdamd, United States, school of biological sciences,university of canterbury,christchurch,new zealand,structural biology research unit,department of clinical laboratory sciences,university of cape town,cape town,south africa,department of plant pathology and emerging pathogens institute,university of florida,gainesville,fl, United States
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Authors
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