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IL-1β/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections
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نویسنده
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slaats j. ,ten oever j. ,van de veerdonk f.l. ,netea m.g.
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منبع
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plos pathogens - 2016 - دوره : 12 - شماره : 12
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چکیده
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The host inflammatory response against infections is characterized by the release of pro-inflammatory cytokines and acute-phase proteins,driving both innate and adaptive arms of the immune response. distinct patterns of circulating cytokines and acute-phase responses have proven indispensable for guiding the diagnosis and management of infectious diseases. this review discusses the profiles of acute-phase proteins and circulating cytokines encountered in viral and bacterial infections. we also propose a model in which the inflammatory response to viral (il-18/ferritin) and bacterial (il-6/crp) infections presents with specific plasma patterns of immune biomarkers. © 2016 slaats et al.
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آدرس
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department of internal medicine and radboud center for infectious diseases,radboud university medical center,nijmegen, Netherlands, department of internal medicine and radboud center for infectious diseases,radboud university medical center,nijmegen, Netherlands, department of internal medicine and radboud center for infectious diseases,radboud university medical center,nijmegen, Netherlands, department of internal medicine and radboud center for infectious diseases,radboud university medical center,nijmegen, Netherlands
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Authors
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