plos pathogens سال:2017 - دوره:13

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plos pathogens
سال:2017 - دوره:13 - شماره:4

A commensal streptococcus hijacks a Pseudomonas aeruginosa exopolysaccharide to promote biofilm formation A derivative of platelet-derived growth factor receptor alpha binds to the trimer of human cytomegalovirus and inhibits entry into fibroblasts and endothelial cells A leucine aminopeptidase is involved in kinetoplast DNA segregation in Trypanosoma brucei A novel Meloidogyne graminicola effector,MgGPP,is secreted into host cells and undergoes glycosylation in concert with proteolysis to suppress plant defenses and promote parasitism A quorum sensing-independent path to stumpy development in Trypanosoma brucei A role for glycolipid biosynthesis in severe fever with thrombocytopenia syndrome virus entry A second wave of Salmonella T3SS1 activity prolongs the lifespan of infected epithelial cells Activated entomopathogenic nematode infective juveniles release lethal venom proteins An APE1 inhibitor reveals critical roles of the redox function of APE1 in KSHV replication and pathogenic phenotypes Analysis of host microRNA function uncovers a role for miR-29b-2-5p in Shigella capture by filopodia Arabidopsis leucine-rich repeat receptor–like kinase NILR1 is required for induction of innate immunity to parasitic nematodes Bacterial amyloid curli acts as a carrier for DNA to elicit an autoimmune response via TLR2 and TLR9 CD8+T cell evasion mandates CD4+T cell control of chronic gamma-herpesvirus infection Correction to: Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues (PLOS Pathogens,(2017),13,3,(e1006219),10.1371/journal.ppat.1006219) DENV up-regulates the HMG-CoA reductase activity through the impairment of AMPK phosphorylation: A potential antiviral target Dendritic cell maturation,but not type I interferon exposure,restricts infection by HTLV-1,and viral transmission to T-cells Dual role of the Toxoplasma gondii clathrin adaptor AP1 in the sorting of rhoptry and microneme proteins and in parasite division Elucidating the structure of an infectious protein Fatty acid DSF binds and allosterically activates histidine kinase RpfC of phytopathogenic bacterium Xanthomonas campestris pv. campestris to regulate quorum-sensing and virulence Filamentous fungal carbon catabolite repression supports metabolic plasticity and stress responses essential for disease progression GP73 represses host innate immune response to promote virus replication by facilitating MAVS and TRAF6 degradation GPATCH3 negatively regulates RLR-mediated innate antiviral responses by disrupting the assembly of VISA signalosome Gre factors-mediated control of hilD transcription is essential for the invasion of epithelial cells by Salmonella enterica serovar Typhimurium Host cell-derived lactate functions as an effector molecule in Neisseria meningitidis microcolony dispersal Human cytomegalovirus glycoprotein complex gH/gL/gO uses PDGFR-α as a key for entry IL-33 receptor ST2 regulates the cognitive impairments associated with experimental cerebral malaria IL-33/ST2 pathway drives regulatory T cell dependent suppression of liver damage upon cytomegalovirus infection Insertion of a ligand to HER2 in gB retargets HSV tropism and obviates the need for activation of the other entry glycoproteins Interferon-inducible ribonuclease ISG20 inhibits hepatitis B virus replication through directly binding to the epsilon stem-loop structure of viral RNA Kaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latency Levels of HIV-1 persistence on antiretroviral therapy are not associated with markers of inflammation or activation Localization of adenovirus morphogenesis players,together with visualization of assembly intermediates and failed products,favor a model where assembly and packaging occur concurrently at the periphery of the replication center Mapping of the Lassa virus LAMP1 binding site reveals unique determinants not shared by other old world arenaviruses Mycobacterium marinum antagonistically induces an autophagic response while repressing the autophagic flux in a TORC1- and ESX-1-dependent manner Neisseria gonorrhoeae infects the human endocervix by activating non-muscle myosin II-mediated epithelial exfoliation Neutrophils and Ly6Chimonocytes collaborate in generating an optimal cytokine response that protects against pulmonary Legionella pneumophila infection Novel decay dynamics revealed for virus-mediated drug activation in cytomegalovirus infection RIPK3 interacts with MAVS to regulate type I IFN-mediated immunity to Influenza A virus infection Regulation of proteinaceous effector expression in phytopathogenic fungi Rotavirus genome replication: Some assembly required Skin-resident CD4+T cells protect against Leishmania major by recruiting and activating inflammatory monocytes TCR stimulation strength is inversely associated with establishment of functional brain-resident memory CD8 T cells during persistent viral infection The Barley stripe mosaic virus γb protein promotes chloroplast-targeted replication by enhancing unwinding of RNA duplexes The Epstein-Barr virus miR-BHRF1-1 targets RNF4 during productive infection to promote the accumulation of SUMO conjugates and the release of infectious virus The importance of model systems: Why we study a virus on the brink of global eradication The not-so-infinite malleability of RNA viruses: Viral and cellular determinants of RNA virus mutation rates The role of integration in oncogenic progression of HPV-associated cancers The role of microsporidian polar tube protein 4 (PTP4) in host cell infection miR-144 attenuates the host response to influenza virus by targeting the TRAF6-IRF7 signaling axis