plos pathogens سال:2017 - دوره:13

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plos pathogens
سال:2017 - دوره:13 - شماره:8

A SIV molecular clone that targets the CNS and induces neuroAIDS in rhesus macaques A parapoxviral virion protein inhibits NF-κB signaling early in infection A trypanosomal orthologue of an intermembrane space chaperone has a non-canonical function in biogenesis of the single mitochondrial inner membrane protein translocase Acquisition of Rab11 and Rab11-Fip2—A novel strategy for Chlamydia pneumoniae early survival B. abortus RNA is the component involved in the down-modulation of MHC-I expression on human monocytes via TLR8 and the EGFR pathway Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission Characterization of novel bangle lectin from Photorhabdus asymbiotica with dual sugar-binding specificity and its effect on host immunity Colonizing opportunistic pathogens (COPs): The beasts in all of us Cross-seeding of prions by aggregated α-synuclein leads to transmissible spongiform encephalopathy Deregulation of KSHV latency conformation by ER-stress and caspase-dependent RAD21-cleavage Destabilizing polymorphism in cervid prion protein hydrophobic core determines prion conformation and conversion efficiency Dynamics and regulation of nuclear import and nuclear movements of HIV-1 complexes Elucidating the function of the prion protein Engaging the CD40-CD40L pathway augments T-helper cell responses and improves control of Mycobacterium tuberculosis infection Enhanced inflammation in New Zealand white rabbits when MERS-CoV reinfection occurs in the absence of neutralizing antibody Experimental study of tuberculosis: From animal models to complex cell systems and organoids Expression of the RNA-binding protein RBP10 promotes the bloodstream-form differentiation state in Trypanosoma brucei Extracellular motility and cell-to-cell transmission of enterohemorrhagic E. coli is driven by EspFU-mediated actin assembly Genome-wide discovery of novel M1T1 group A streptococcal determinants important for fitness and virulence during soft-tissue infection Getting the flu: 5 key facts about influenza virus evolution HIV-1 epitopes presented by MHC class I types associated with superior immune containment of viremia have highly constrained fitness landscapes HRS plays an important role for TLR7 signaling to orchestrate inflammation and innate immunity upon EV71 infection Herpesviruses shape tumour microenvironment through exosomal transfer of viral microRNAs Impact of prior flavivirus immunity on Zika virus infection in rhesus macaques Infection-adapted emergency hematopoiesis promotes visceral leishmaniasis Influenza NS1 directly modulates Hedgehog signaling during infection Inhibition of caspase-1 or gasdermin-D enable caspase-8 activation in the Naip5/NLRC4/ASC inflammasome Interaction of the cyclic-di-GMP binding protein FimX and the Type 4 pilus assembly ATPase promotes pilus assembly L-type lectin receptor kinases: New forces in plant immunity Ligation of Dectin-2 with a novel microbial ligand promotes adjuvant activity for vaccination Microbiome-mediated neutrophil recruitment via CXCR2 and protection from amebic colitis Molecular mechanisms of mucormycosis—The bitter and the sweet Multi-functional mechanisms of immune evasion by the streptococcal complement inhibitor C5a peptidase Multikingdom microscale models Murine gammaherpesvirus M2 antigen modulates splenic B cell activation and terminal differentiation in vivo Natural killer cells attenuate cytomegalovirus-induced hearing loss in mice Nuclease escape elements protect messenger RNA against cleavage by multiple viral endonucleases O-acetylation of the serine-rich repeat glycoprotein GspB is coordinated with accessory Sec transport P2X7 receptor drives Th1 cell differentiation and controls the follicular helper T cell population to protect against Plasmodium chabaudi malaria Persistent mycobacteria evade an antibacterial program mediated by phagolysosomal TLR7/8/MyD88 in human primary macrophages Primate lentiviruses use at least three alternative strategies to suppress NF-κB-mediated immune activation Protective capacity of neutralizing and non-neutralizing antibodies against glycoprotein B of cytomegalovirus Pseudomonas aeruginosa ExlA and Serratia marcescens ShlA trigger cadherin cleavage by promoting calcium influx and ADAM10 activation Pseudomonas aeruginosa ExoU augments neutrophil transepithelial migration Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing Structural analysis of P. falciparum KAHRP and PfEMP1 complexes with host erythrocyte spectrin suggests a model for cytoadherent knob protrusions Structural studies demonstrating a bacteriophage-like replication cycle of the eukaryote-infecting Paramecium bursaria chlorella virus-1 T cell expression of IL-18R and DR3 is essential for non-cognate stimulation of Th1 cells and optimal clearance of intracellular bacteria The 5'-poly(A) leader of poxvirus mRNA confers a translational advantage that can be achieved in cells with impaired cap-dependent translation The AraC Negative Regulator family modulates the activity of histone-like proteins in pathogenic bacteria The macrophage cytoskeleton acts as a contact sensor upon interaction with Entamoeba histolytica to trigger IL-1β secretion The plasmid-encoded Ipf and Klf fimbriae display different expression and varying roles in the virulence of Salmonella enterica serovar Infantis in mouse vs. avian hosts The replication initiator protein of a geminivirus interacts with host monoubiquitination machinery and stimulates transcription of the viral genome The role of human immunity and social behavior in shaping influenza evolution The role of the C-terminal D0 domain of flagellin in activation of Toll like receptor 5 Tissue-specific control of latent CMV reactivation by regulatory T cells Transient expression of ZBTB32 in anti-viral CD8+T cells limits the magnitude of the effector response and the generation of memory Yes,research matters