|
|
|
|
Identification of GBV-D,a novel GB-like flavivirus from old world frugivorous bats (pteropus giganteus) in Bangladesh
|
|
|
|
|
|
|
|
نویسنده
|
epstein j.h. ,quan p.-l. ,briese t. ,street c. ,jabado o. ,conlan s. ,khan s.a. ,verdugo d. ,hossain m.j. ,hutchison s.k. ,egholm m. ,luby s.p. ,daszak p. ,lipkin w.i.
|
|
منبع
|
plos pathogens - 2010 - دوره : 6 - شماره : 7 - صفحه:1 -8
|
|
چکیده
|
Bats are reservoirs for a wide range of zoonotic agents including lyssa-,henipah-,sars-like corona-,marburg-,ebola-,and astroviruses. in an effort to survey for the presence of other infectious agents,known and unknown,we screened sera from 16 pteropus giganteus bats from faridpur,bangladesh,using high-throughput pyrosequencing. sequence analyses indicated the presence of a previously undescribed virus that has approximately 50% identity at the amino acid level to gb virus a and c (gbv-a and -c). viral nucleic acid was present in 5 of 98 sera (5%) from a single colony of free-ranging bats. infection was not associated with evidence of hepatitis or hepatic dysfunction. phylogenetic analysis indicates that this first gbv-like flavivirus reported in bats constitutes a distinct species within the flaviviridae family and is ancestral to the gbv-a and -c virus clades. © 2010 epstein et al.
|
|
|
|
|
آدرس
|
conservation medicine program,wildlife trust,new york,ny, United States, center for infection and immunity,mailman school of public health,columbia university,new york,ny, United States, center for infection and immunity,mailman school of public health,columbia university,new york,ny, United States, center for infection and immunity,mailman school of public health,columbia university,new york,ny, United States, center for infection and immunity,mailman school of public health,columbia university,new york,ny, United States, center for infection and immunity,mailman school of public health,columbia university,new york,ny, United States, conservation medicine program,wildlife trust,new york,ny,united states,chittagong veterinary and animal sciences university,chittagong, Bangladesh, center for infection and immunity,mailman school of public health,columbia university,new york,ny, United States, programme on infectious disease and vaccine sciences,international centre for diarrheal disease research,bangladesh (icddr,b),dhaka, Bangladesh, 454 life sciences,branford,ct, United States, 454 life sciences,branford,ct, United States, programme on infectious disease and vaccine sciences,international centre for diarrheal disease research,bangladesh (icddr,b),dhaka, Bangladesh, conservation medicine program,wildlife trust,new york,ny, United States, center for infection and immunity,mailman school of public health,columbia university,new york,ny, United States
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Authors
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|