plos pathogens سال:2012 - دوره:8

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plos pathogens
سال:2012 - دوره:8 - شماره:2

A P-loop mutation in Gα subunits prevents transition to the active state: Implications for G-protein signaling in fungal pathogenesis A bacterial acetyltransferase destroys plant microtubule networks and blocks secretion A co-opted DEAD-box RNA helicase enhances tombusvirus plus-strand synthesis A putative homologue of CDC20/CDH1 in the malaria parasite is essential for male gamete development Absence of HIV-1 evolution in the gut-associated lymphoid tissue from patients on combination antiviral therapy initiated during primary infection Behavioral and immune responses to infection require Gαq- RhoA signaling in C. elegans Biochemical properties of highly neuroinvasive prion strains Borrelia burgdorferi requires the alternative sigma factor RpoS for dissemination within the vector during tick-to-mammal transmission ChLae1 and ChVel1 regulate T-toxin production,virulence,oxidative stress response,and development of the maize pathogen Cochliobolus heterostrophus Characterising the mucosal and systemic immune responses to experimental human hookworm infection Characterization of monomeric intermediates during VSV glycoprotein structural transition Concerted actions of a thermo-labile regulator and a unique intergenic RNA thermosensor control Yersinia virulence Degradation of cellular miR-27 by a novel,highly abundant viral transcript is important for efficient virus replication in vivo Depletion of dendritic cells enhances innate anti-bacterial host defense through modulation of phagocyte homeostasis Different chitin synthase genes are required for various developmental and plant infection processes in the rice blast fungus Magnaporthe oryzae Discrete cyclic di-GMP-dependent control of bacterial predation versus axenic growth in Bdellovibrio bacteriovorus Early priming minimizes the age-related immune compromise of CD8+ T cell diversity and function Efficient capture of infected neutrophils by dendritic cells in the skin inhibits the early anti-leishmania response Enhancement of chemokine function as an immunomodulatory strategy employed by human herpesviruses Essential roles for soluble virion-associated heparan sulfonated proteoglycans and growth factors in human papillomavirus infections FOXO3 regulates CD8 T cell memory by T cell-intrinsic mechanisms Five questions about viral trafficking in neurons Genetic pathway in acquisition and loss of vancomycin resistance in a methicillin resistant Staphylococcus aureus (MRSA) strain of clonal type USA300 Genome-wide transcriptional profiling of appressorium development by the rice blast fungus Magnaporthe oryzae How do microbial pathogens make CENs? Immune subversion and quorum-sensing shape the variation in infectious dose among bacterial pathogens Introgression of ivermectin resistance genes into a susceptible Haemonchus contortus strain by multiple backcrossing Mechanisms of pathogenesis,infective dose and virulence in human parasites Msb2 shedding protects Candida albicans against antimicrobial peptides Mycobacterium tuberculosis ClpP1 and ClpP2 function together in protein degradation and are required for viability in vitro and during infection Nonequivalence of classical MHC class I loci in ability to direct effective antiviral immunity Novel transmembrane receptor involved in phagosome transport of lysozymes and β-hexosaminidase in the enteric protozoan Entamoeba histolytica Phagosomal rupture by Mycobacterium tuberculosis results in toxicity and host cell death Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection Population genetic analyses reveal the African origin and strain variation of Cryptococcus neoformans var. grubii Portrait of Candida albicans adherence regulators Selecting an invertebrate model host for the study of fungal pathogenesis Specialized peptidoglycan hydrolases sculpt the intra-bacterial niche of predatory Bdellovibrio and increase population fitness Structural and functional insights into the pilotin-secretin complex of the type II secretion system Substance P causes seizures in neurocysticercosis The Arabidopsis lectin receptor kinase LecRK-V.5 represses stomatal immunity induced by Pseudomonas syringae pv. tomato DC3000 The B-cell specific transcription factor,Oct-2,promotes Epstein-Barr virus latency by inhibiting the viral immediate-early protein,BZLF1 The CTLA-4 and PD-1/PD-l1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology The Legionella pneumophila effector VipA is an actin nucleator that alters host cell organelle trafficking The TPR domain in the host Cyp40-like cyclophilin binds to the viral replication protein and inhibits the assembly of the tombusviral replicase The ebola virus interferon antagonist VP24 directly binds STAT1 and has a novel,pyramidal fold The invasive capacity of HPV transformed cells requires the hDlg-dependent enhancement of SGEF/RhoG activity The relative importance of innate immune priming in Wolbachia-mediated dengue interference The role of animal models for research on severe malaria Transcriptional activation of the adenoviral genome is mediated by capsid protein VI Transient reversal of episome silencing precedes VP16-dependent transcription during reactivation of latent HSV-1 in neurons Tuberculosis and HIV co-infection Viral cyclins mediate separate phases of infection by integrating functions of distinct mammalian cyclins Viral mediated redirection of NEMO/IKKγ to autophagosomes curtails the inflammatory cascade