plos pathogens سال:2012 - دوره:8

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plos pathogens
سال:2012 - دوره:8 - شماره:5

2′-O methylation of the viral mRNA cap by West Nile virus evades Ifit1-dependent and -independent mechanisms of host restriction in vivo A new evolutionary model for hepatitis C virus chronic infection A single polar residue and distinct membrane topologies impact the function of the infectious bronchitis coronavirus E protein ATG5 is essential for ATG8-dependent autophagy and mitochondrial homeostasis in Leishmania major Age of the association between Helicobacter pylori and man Age-dependent TLR3 expression of the intestinal epithelium contributes to rotavirus susceptibility Analysis of functional differences between hepatitis C virus NS5A of genotypes 1-7 in infectious cell culture systems CAMP and EPAC are key players in the regulation of the signal transduction pathway involved in the α-hemolysin autophagic response CD200 receptor controls sex-specific TLR7 responses to viral infection Cellular levels and binding of c-di-GMP control subcellular localization and activity of the Vibrio cholerae transcriptional regulator VpsT Chitohexaose activates macrophages by alternate pathway through TLR4 and blocks endotoxemia Comparative genomics reveals two novel RNAi factors in Trypanosoma brucei and provides insight into the core machinery Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape Entry of herpes simplex virus type 1 (HSV-1) into the distal axons of trigeminal neurons favors the onset of nonproductive,silent infection Epstein-Barr virus infection of naïve B cells in vitro frequently selects clones with mutated immunoglobulin genotypes: Implications for virus biology Epstein-barr virus-encoded LMP1 interacts with FGD4 to activate Cdc42 and thereby promote migration of nasopharyngeal carcinoma cells Evolution of an Eurasian avian-like influenza virus in naïve and vaccinated pigs Evolutionary reconstructions of the transferrin receptor of caniforms supports canine parvovirus being a re-emerged and not a novel pathogen in dogs Experimental evolution of Legionella pneumophila in mouse macrophages leads to strains with altered determinants of environmental survival Extracellular superoxide dismutase protects Histoplasma yeast cells from host-derived oxidative stress Five questions on prion diseases From molecular genetics to phylodynamics: Evolutionary relevance of mutation rates across viruses Functional analysis of NopM,a novel E3 ubiquitin ligase (NEL) domain effector of Rhizobium sp. strain NGR234 Gammaherpesvirus latency accentuates EAE pathogenesis: Relevance to Epstein-Barr virus and multiple sclerosis Global analysis of the evolution and mechanism of echinocandin resistance in Candida glabrata Hsp90 interacts specifically with viral RNA and differentially regulates replication initiation of Bamboo mosaic virus and associated satellite RNA Hydrophobins-unique fungal proteins Identification and functional analysis of the S-layer protein SplA of Paenibacillus larvae,the causative agent of American Foulbrood of honey bees Immunogenetic mechanisms driving norovirus GII.4 antigenic variation In vitro and in vivo isolation and characterization of Duvenhage virus Induction of GADD34 is necessary for dsRNA-dependent interferon-β production and participates in the control of Chikungunya virus infection Influence of microbiota on viral infections Interferon-induced Ifit2/ISG54 protects mice from lethal VSV neuropathogenesis KSHV PAN RNA associates with demethylases UTX and JMJD3 to activate lytic replication through a physical interaction with the virus genome Large-scale gene disruption in Magnaporthe oryzae identifies MC69,a secreted protein required for infection by monocot and dicot fungal pathogens Lysogeny with Shiga toxin 2-encoding bacteriophages represses type III secretion in enterohemorrhagic Escherichia coli MiR-27b targets KSRP to coordinate TLR4-mediated epithelial defense against Cryptosporidium parvum infection Midgut microbiota of the malaria mosquito vector Anopheles gambiae and interactions with Plasmodium falciparum infection Negative selection by an endogenous retrovirus promotes a higher-avidity CD4+ T cell response to retroviral infection Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis Pathogen-induced proapoptotic phenotype and high CD95 (Fas) expression accompany a suboptimal CD8+ T-cell response: Reversal by adenoviral vaccine Pdl1 is a putative lipase that enhances Photorhabdus toxin complex secretion Plasticity of the β-trefoil protein fold in the recognition and control of invertebrate predators and parasites by a fungal defence system Polydnavirus Ank proteins bind NF-κB homodimers and inhibit processing of Relish Probiotic Bifidobacterium breve induces IL-10-producing Tr1 cells in the colon Rates of viral evolution are linked to host geography in bat rabies Structure and functional analysis of the RNA- and viral phosphoprotein-binding domain of respiratory syncytial virus M2-1 protein Synchronized retrovirus fusion in cells expressing alternative receptor isoforms releases the viral core into distinct sub-cellular compartments The EBV immunoevasins vIL-10 and BNLF2a protect newly infected B cells from immune recognition and elimination The NDR/LATS kinase Cbk1 controls the activity of the transcriptional regulator Bcr1 during biofilm formation in Candida albicans The Ustilago maydis effector Pep1 suppresses plant immunity by inhibition of host peroxidase activity The Wor1-like protein Fgp1 regulates pathogenicity,toxin synthesis and reproduction in the phytopathogenic fungus Fusarium graminearum The [Het-s] prion,an amyloid fold as a cell death activation trigger The effect of human factor H on immunogenicity of meningococcal native outer membrane vesicle vaccines with over-expressed factor H binding protein The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition The lipopolysaccharide from Capnocytophaga canimorsus reveals an unexpected role of the core-oligosaccharide in MD-2 binding The ubiquitin/proteasome system mediates entry and endosomal trafficking of Kaposi's sarcoma-associated herpesvirus in endothelial cells Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7 Type III secretion in Yersinia: Injectisome or not? Vaccines against tuberculosis: Where are we and where do we need to go? Vitamin D inhibits human immunodeficiency virus type 1 and Mycobacterium tuberculosis infection in macrophages through the induction of autophagy