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Diagnostics in Ebola Virus Disease in Resource-Rich and Resource-Limited Settings
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نویسنده
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shorten r.j. ,brown c.s. ,jacobs m. ,rattenbury s. ,simpson a.j. ,mepham s.
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منبع
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plos neglected tropical diseases - 2016 - دوره : 10 - شماره : 10
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چکیده
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The ebola virus disease (evd) outbreak in west africa was unprecedented in scale and location. limited access to both diagnostic and supportive pathology assays in both resource-rich and resource-limited settings had a detrimental effect on the identification and isolation of cases as well as individual patient management. limited access to such assays in resource-rich settings resulted in delays in differentiating evd from other illnesses in returning travellers,in turn utilising valuable resources until a diagnosis could be made. this had a much greater impact in west africa,where it contributed to the initial failure to contain the outbreak. this review explores diagnostic assays of use in evd in both resource-rich and resource-limited settings,including their respective limitations,and some novel assays and approaches that may be of use in future outbreaks. © 2016 shorten et al.
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آدرس
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public health laboratory manchester,manchester royal infirmary,manchester,united kingdom,university college london,centre for clinical microbiology,department of infection,london, United Kingdom, hospital for tropical diseases,university college london hospital,london,united kingdom,king’s sierra leone partnership,king’s centre for global health,king’s college london,king’s health partners,london, United Kingdom, department of infection,royal free london nhs foundation trust,london, United Kingdom, department of infection,royal free london nhs foundation trust,london, United Kingdom, university college london,centre for clinical microbiology,department of infection,london,united kingdom,rare and imported pathogens laboratory,public health england,salisbury, United Kingdom, department of infection,royal free london nhs foundation trust,london, United Kingdom
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Authors
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