>
Fa   |   Ar   |   En
   Isolation and sequencing of Dashli virus,a novel Sicilian-like virus in sandflies from Iran; genetic and phylogenetic evidence for the creation of one novel species within the Phlebovirus genus in the Bunyaviridae family  
   
نویسنده alkan c. ,moin vaziri v. ,ayhan n. ,badakhshan m. ,bichaud l. ,rahbarian n. ,javadian e.-a. ,alten b. ,de lamballerie x. ,charrel r.n.
منبع plos neglected tropical diseases - 2017 - دوره : 11 - شماره : 12
چکیده    Phlebotomine sandflies are vectors of phleboviruses that cause sandfly fever or meningitis with significant implications for public health. although several strains of these viruses had been isolated in iran in the late 1970's,there was no recent data about the present situation at the outset of this study. entomological investigations performed in 2009 and 2011 in iran collected 4,770 sandflies from 10 different regions. based on morphological identification,they were sorted into 315 pools according to species,sex,trapping station and date of capture. a phlebovirus,provisionally named dashli virus (dashv),was isolated from one pool of sergentomyia spp,and subsequently dashv rna was detected in a second pool of phlebotomus papatasi. genetic and phylogenetic analyses based on complete coding genomic sequences indicated that (i) dashv is most closely related to the iranian isolates of sandfly fever sicilian virus [sfsv],(ii) there is a common ancestor to dashv,sandfly fever sicilian- (sfs) and sfs-like viruses isolated in italy,india,turkey,and cyprus (lineage i),(iii) dashv is more distantly related with corfou and toros viruses (lineage ii) although common ancestry is supported with 100% bootstrap,(iii) lineage i can be subdivided into sublineage ia including all sfsv,sfcv and sftv except those isolated in iran which forms sublineage ib (dashv). accordingly,we suggest to approve sandfly fever sicilian virus species consisting of the all aforementioned viruses. owing that most of these viruses have been identified in human patients with febrile illness,dashv should be considered as a potential human pathogen in iran. © 2017 alkan et al.
آدرس umr emergence des pathologies virales (epv: aix-marseille univ—ird 190—inserm 1207—ehesp),marseille,france,fondation ihu mediterranee infection,aphm public hospitals of marseille,marseille, France, department of parasitology and mycology,school of medicine,shahid beheshti university of medical sciences,tehran, ایران, umr emergence des pathologies virales (epv: aix-marseille univ—ird 190—inserm 1207—ehesp),marseille,france,fondation ihu mediterranee infection,aphm public hospitals of marseille,marseille, France, department of medical entomology and vector control,school of public health and institute of public health research,tehran university of medical sciences,tehran, ایران, umr emergence des pathologies virales (epv: aix-marseille univ—ird 190—inserm 1207—ehesp),marseille,france,fondation ihu mediterranee infection,aphm public hospitals of marseille,marseille, France, department of parasitology and mycology,school of medicine,shahid beheshti university of medical sciences,tehran,iran,cellular and molecular biology research center,shahid beheshti university of medical sciences,tehran, ایران, department of medical entomology and vector control,school of public health and institute of public health research,tehran university of medical sciences,tehran, ایران, faculty of science,department of biology,ecology section,esr laboratories,hacettepe university,ankara, Turkey, umr emergence des pathologies virales (epv: aix-marseille univ—ird 190—inserm 1207—ehesp),marseille,france,fondation ihu mediterranee infection,aphm public hospitals of marseille,marseille, France, umr emergence des pathologies virales (epv: aix-marseille univ—ird 190—inserm 1207—ehesp),marseille,france,fondation ihu mediterranee infection,aphm public hospitals of marseille,marseille, France
 
     
   
Authors
  
 
 

Copyright 2023
Islamic World Science Citation Center
All Rights Reserved