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Development of an immunochromatographic test for diagnosis of visceral leishmaniasis based on detection of a circulating antigen
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نویسنده
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gao c.-h. ,yang y.-t. ,shi f. ,wang j.-y. ,steverding d. ,wang x.
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منبع
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plos neglected tropical diseases - 2015 - دوره : 9 - شماره : 6
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چکیده
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Visceral leishmaniasis (vl) is a life-threatening disease caused by protozoan parasites of the leishmania donovani complex. early case detection followed by adequate treatment is essential to the control of vl. however,the available diagnostic tests are either invasive and require considerable expertise (parasitological demonstration of the parasite in tissue smears) or unable to distinguish between past and active infection (serological methods). therefore,we aimed to develop a lateral flow assay in the form of an immunochromatographic test (ict) device based on the detection of a circulating leishmania antigen using monoclonal antibodies (mabs). © 2015 gao et al.
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آدرس
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national institute of parasitic diseases,chinese center for disease control and prevention,laboratory of parasite and vector,ministry of public health,national centre for international research on tropical diseases,who collaborating center for malaria,schistosomiasis and filariasis,shanghai, China, national institute of parasitic diseases,chinese center for disease control and prevention,laboratory of parasite and vector,ministry of public health,national centre for international research on tropical diseases,who collaborating center for malaria,schistosomiasis and filariasis,shanghai, China, national institute of parasitic diseases,chinese center for disease control and prevention,laboratory of parasite and vector,ministry of public health,national centre for international research on tropical diseases,who collaborating center for malaria,schistosomiasis and filariasis,shanghai, China, national institute of parasitic diseases,chinese center for disease control and prevention,laboratory of parasite and vector,ministry of public health,national centre for international research on tropical diseases,who collaborating center for malaria,schistosomiasis and filariasis,shanghai, China, biomedical research centre,norwich medical school,norwich research park,university of east anglia,norwich, United Kingdom, biomedical research centre,norwich medical school,norwich research park,university of east anglia,norwich, United Kingdom
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Authors
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