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   Epidemiological and molecular characterization of dengue virus circulating in Bhutan,2013-2014  
   
نویسنده zangmo s. ,klungthong c. ,chinnawirotpisan p. ,tantimavanich s. ,kosoltanapiwat n. ,thaisomboonsuk b. ,phuntsho k. ,wangchuk s. ,yoon i.-k. ,fernandez s.
منبع plos neglected tropical diseases - 2015 - دوره : 9 - شماره : 8
چکیده    Dengue is one of the most significant public health problems in tropical and subtropical countries,and is increasingly being detected in traditionally non-endemic areas. in bhutan,dengue virus (denv) has only recently been detected and limited information is available. in this study,we analyzed the epidemiological and molecular characteristics of denv in two southern districts in bhutan from 2013–2014. during this period,379 patients were clinically diagnosed with suspected dengue,of whom 119 (31.4%) were positive for denv infection by ns1 elisa and/or nested rt-pcr. denv serotypes 1,2 and 3 were detected with denv-1 being predominant. phylogenetic analysis of denv-1 using envelope gene demonstrated genotype v,closely related to strains from northern india. © 2015 zangmo et al.
آدرس mahidol university,bangkok,thailand,public health laboratory,ministry of health,thimphu, Bhutan, department of virology,armed force research institute of medical sciences,bangkok, Thailand, department of virology,armed force research institute of medical sciences,bangkok, Thailand, mahidol university,bangkok, Thailand, mahidol university,bangkok, Thailand, department of virology,armed force research institute of medical sciences,bangkok, Thailand, public health laboratory,ministry of health,thimphu, Bhutan, public health laboratory,ministry of health,thimphu, Bhutan, department of virology,armed force research institute of medical sciences,bangkok, Thailand, department of virology,armed force research institute of medical sciences,bangkok, Thailand
 
     
   
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