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New Players in the Same Old Game: Disturbance of Group 2 Innate Lymphoid Cells in HIV-1 and Mycobacterium leprae Co-infected Patients
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نویسنده
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papotto p.h. ,maeda s. ,tomimori j. ,xavier m.b. ,rizzo l.v. ,kallas e.g. ,carvalho k.i.
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منبع
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plos neglected tropical diseases - 2015 - دوره : 9 - شماره : 9
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چکیده
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Leprosy control is achieved through a fine-tuning of th1 and th2 immune response pattern balance. given the increasing epidemiological overlay of hiv and m. leprae infections,immune response in co-infected patients consists in an important contemporary issue. here we describe for the first time the innate lymphoid cells compartment in peripheral blood of leprosy and hiv/m. leprae co-infected patients,and show that co-infection increases group 2 innate lymphoid whilst decreasing group 1 innate lymphoid cells frequencies and function. © 2015 papotto et al.
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آدرس
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hospital israelita albert einstein,instituto israelita de ensino e pesquisa,são paulo, Brazil, universidade federal de são paulo,dermatology department,são paulo, Brazil, universidade federal de são paulo,dermatology department,são paulo, Brazil, universidade federal do pará,dermatology department,pará, Brazil, hospital israelita albert einstein,instituto israelita de ensino e pesquisa,são paulo, Brazil, universidade de são paulo,faculdade de medicina,disciplina de imunologia clínica e alergia (lim60),são paulo, Brazil, hospital israelita albert einstein,instituto israelita de ensino e pesquisa,são paulo, Brazil
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Authors
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