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Global Spread of Human Chromoblastomycosis Is Driven by Recombinant Cladophialophora carrionii and Predominantly Clonal Fonsecaea Species
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نویسنده
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deng s. ,tsui c.k.m. ,gerrits van den ende a.h.g. ,yang l. ,najafzadeh m.j. ,badali h. ,li r. ,hagen f. ,meis j.f. ,sun j. ,dolatabadi s. ,papierok b. ,pan w. ,de hoog g.s. ,liao w.
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منبع
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plos neglected tropical diseases - 2015 - دوره : 9 - شماره : 10
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چکیده
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Global distribution patterns of cladophialophora carrionii,agent of human chromoblastomycosis in arid climates of africa,asia,australia,central-and south-america,were compared with similar data of the vicarious fonsecaea spp.,agents of the disease in tropical rain forests. population diversities among 73 c. carrionii strains and 60 strains of three fonsecaea species were analyzed for rdna its,partial β-tubulin,and amplified fragment-length polymorphism (aflp) fingerprints. populations differed significantly between continents. lowest haplotype diversity was found in south american populations,while african strains were the most diverse. gene flow was noted between the african population and all other continents. the general pattern of fonsecaea agents of chromoblastomycosis differed significantly from that of c. carrionii and revealed deeper divergence among three differentiated species with smaller numbers of haplotypes,indicating a longer evolutionary history. © 2015 deng et al.
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آدرس
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shanghai institute of medical mycology,changzheng hospital,shanghai,china,first hospital of xinjiang medical university,xinjiang,china,cbs-knaw fungal biodiversity centre,utrecht, Netherlands, british columbia public health microbiology & reference laboratory at bccdc site,provincial health services authority,vancouver, Canada, cbs-knaw fungal biodiversity centre,utrecht, Netherlands, cbs-knaw fungal biodiversity centre,utrecht, Netherlands, department of parasitology and mycology & cancer molecular pathology research center,ghaem hospital,school of medicine,mashhad university of medical sciences,mashhad, ایران, department of medical mycology and parasitology / invasive fungi research center (ifrc),school of medicine,mazandaran university of medical sciences,sari, ایران, research center for medical mycology,beijing medical university,beijing, China, department of medical microbiology and infectious diseases,canisius wilhelmina hospital,nijmegen, Netherlands, department of medical microbiology and infectious diseases,canisius wilhelmina hospital,nijmegen,netherlands,radboud university medical center,nijmegen, Netherlands, guangdong provincial institute of public health,guangdong provincial center for disease control and prevention,guangzhou, China, cbs-knaw fungal biodiversity centre,utrecht,netherlands,cellular and molecular research center,sabzevar university of medical sciences,sabzevar, ایران, institute pasteur,paris, France, shanghai institute of medical mycology,changzheng hospital,shanghai, China, shanghai institute of medical mycology,changzheng hospital,shanghai,china,cbs-knaw fungal biodiversity centre,utrecht,netherlands,research center for medical mycology,beijing medical university,beijing,china,cellular and molecular research center,sabzevar university of medical sciences,sabzevar,iran,king abdulaziz university,jeddah, Saudi Arabia, shanghai institute of medical mycology,changzheng hospital,shanghai, China
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Authors
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