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   An Epidemic of Dengue-1 in a Remote Village in Rural Laos  
   
نویسنده dubot-pérès a. ,vongphrachanh p. ,denny j. ,phetsouvanh r. ,linthavong s. ,sengkeopraseuth b. ,khasing a. ,xaythideth v. ,moore c.e. ,vongsouvath m. ,castonguay-vanier j. ,sibounheuang b. ,taojaikong t. ,chanthongthip a. ,de lamballerie x. ,newton p.n.
منبع plos neglected tropical diseases - 2013 - دوره : 7 - شماره : 8
چکیده    In the lao pdr (laos),urban dengue is an increasingly recognised public health problem. we describe a dengue-1 virus outbreak in a rural northwestern lao forest village during the cool season of 2008. the isolated strain was genotypically endemic and not sylvatic, belonging to the genotype 1,asia 3 clade. phylogenetic analyses of 37 other dengue-1 sequences from diverse areas of laos between 2007 and 2010 showed that the geographic distribution of some strains remained focal overtime while others were dispersed throughout the country. evidence that dengue viruses have broad circulation in the region,crossing country borders,was also obtained. whether the outbreak arose from dengue importation from an urban centre into a dengue-naïve community or crossed into the village from a forest cycle is unknown. more epidemiological and entomological investigations are required to understand dengue epidemiology and the importance of rural and forest dengue dynamics in laos. © 2013 dubot-pérès et al.
آدرس umr-d 190 emergence des pathologies virales,aix-marseille université,ird french institute of research for development,ehesp french school of public health,marseille,france,lao-oxford-mahosot hospital - wellcome trust research unit (lomwru),microbiology laboratory,mahosot hospital,vientiane,laos,centre for tropical medicine,nuffield department of clinical medicine,university of oxford,churchill hospital,oxford, United Kingdom, national centre for laboratory and epidemiology,ministry of health,vientiane, Laos, world health organization - lao people's democratic republic,vientiane, Laos, lao-oxford-mahosot hospital - wellcome trust research unit (lomwru),microbiology laboratory,mahosot hospital,vientiane,laos,centre for tropical medicine,nuffield department of clinical medicine,university of oxford,churchill hospital,oxford, United Kingdom, xayabury provincial health department,xayabury, Laos, national centre for laboratory and epidemiology,ministry of health,vientiane, Laos, national centre for laboratory and epidemiology,ministry of health,vientiane, Laos, national centre for laboratory and epidemiology,ministry of health,vientiane, Laos, lao-oxford-mahosot hospital - wellcome trust research unit (lomwru),microbiology laboratory,mahosot hospital,vientiane,laos,centre for tropical medicine,nuffield department of clinical medicine,university of oxford,churchill hospital,oxford, United Kingdom, lao-oxford-mahosot hospital - wellcome trust research unit (lomwru),microbiology laboratory,mahosot hospital,vientiane, Laos, lao-oxford-mahosot hospital - wellcome trust research unit (lomwru),microbiology laboratory,mahosot hospital,vientiane,laos,centre for tropical medicine,nuffield department of clinical medicine,university of oxford,churchill hospital,oxford, United Kingdom, lao-oxford-mahosot hospital - wellcome trust research unit (lomwru),microbiology laboratory,mahosot hospital,vientiane, Laos, lao-oxford-mahosot hospital - wellcome trust research unit (lomwru),microbiology laboratory,mahosot hospital,vientiane, Laos, lao-oxford-mahosot hospital - wellcome trust research unit (lomwru),microbiology laboratory,mahosot hospital,vientiane, Laos, umr-d 190 emergence des pathologies virales,aix-marseille université,ird french institute of research for development,ehesp french school of public health,marseille, France, lao-oxford-mahosot hospital - wellcome trust research unit (lomwru),microbiology laboratory,mahosot hospital,vientiane,laos,centre for tropical medicine,nuffield department of clinical medicine,university of oxford,churchill hospital,oxford, United Kingdom
 
     
   
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